Open Access

Tumor‑targeting bacterial therapy: A potential treatment for oral cancer (Review)

  • Authors:
    • Sai Liu
    • Xiaoping Xu
    • Xin Zeng
    • Longjiang Li
    • Qianming Chen
    • Jing Li
  • View Affiliations

  • Published online on: September 11, 2014     https://doi.org/10.3892/ol.2014.2525
  • Pages: 2359-2366
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Abstract

Certain obligate or facultative anaerobic bacteria, which exhibit an inherent ability to colonize solid tumors in vivo, may be used in tumor targeting. As genetically manipulated bacteria may actively and specifically penetrate into the tumor tissue, bacterial therapy is becoming a promising approach in the treatment of tumors. However, to the best of our knowledge, no reports have been published thus far regarding the bacterial treatment of oral cancer, one of the most common types of cancer worldwide. In this review, the progress in the understanding of bacterial strategies used in tumor‑targeted therapy is discussed and particular bacterial strains that may have great therapeutic potential in oral squamous cell carcinoma (OSCC) tumor‑targeted therapy are predicted as determined by previous studies.
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December-2014
Volume 8 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Liu S, Xu X, Zeng X, Li L, Chen Q and Li J: Tumor‑targeting bacterial therapy: A potential treatment for oral cancer (Review). Oncol Lett 8: 2359-2366, 2014.
APA
Liu, S., Xu, X., Zeng, X., Li, L., Chen, Q., & Li, J. (2014). Tumor‑targeting bacterial therapy: A potential treatment for oral cancer (Review). Oncology Letters, 8, 2359-2366. https://doi.org/10.3892/ol.2014.2525
MLA
Liu, S., Xu, X., Zeng, X., Li, L., Chen, Q., Li, J."Tumor‑targeting bacterial therapy: A potential treatment for oral cancer (Review)". Oncology Letters 8.6 (2014): 2359-2366.
Chicago
Liu, S., Xu, X., Zeng, X., Li, L., Chen, Q., Li, J."Tumor‑targeting bacterial therapy: A potential treatment for oral cancer (Review)". Oncology Letters 8, no. 6 (2014): 2359-2366. https://doi.org/10.3892/ol.2014.2525