Computed tomography findings of a solitary extramedullary plasmacytoma of the spleen: A case report and literature review
- Authors:
- Ying Wang
- Li Yang
- Zi-Hua Qian
- Xiu-Liang Zhu
- Ri-Sheng Yu
View Affiliations
Affiliations: Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China
- Published online on: November 7, 2014 https://doi.org/10.3892/ol.2014.2691
-
Pages:
219-222
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Solitary extramedullary plasmacytoma (EMP) of the spleen is a rare condition. The present study describes the case of a 23‑year‑old female with an extremely rare solitary EMP of the spleen. Upon examination, the tumor demonstrated unusual and notable multiple‑phase spiral computed tomography (CT) findings. The lesion was a solitary, well‑defined mass, with areas of variable splenic necrosis and cystic degeneration. Contrast‑enhanced CT revealed progressive enhancement of the lesion in the cystic wall, internal septa and solid portion, a finding that has not previously been described. The patient underwent a splenectomy and recovered without complications. No evidence of tumor recurrence has occurred during the past two years of follow-up. To the best of our knowledge, this is the first study to examine the CT findings of a solitary EMP of the spleen. The study aimed to investigate the imaging features of solitary EMP, in particular the multiple‑phase spiral CT findings, and raise awareness of the disease to reduce misdiagnoses.
View References
1
|
Horny HP and Kaiserling E: Involvement of
the larynx by hemopoietic neoplasms. An investigation of autopsy
cases and review of the literature. Pathol Res Pract. 191:130–138.
1995. View Article : Google Scholar : PubMed/NCBI
|
2
|
Perry-Thornton E, Verly GP, Karkala J and
Walker M: An unusual presentation of multiple myeloma: primary
plasmacytoma of the spleen. J Natl Med Assoc. 81:1095–1096.
1989.PubMed/NCBI
|
3
|
Colović MD, Janković GM, Colović RB and
Martinović-Cemerikić VM: Non-secretory solitary plasmacytoma of the
spleen. Med Oncol. 15:286–288. 1998. View Article : Google Scholar
|
4
|
Horny HP, Saal J and Kaiserling E: Primary
splenic presentation of plasma cell dyscrasia: report of two cases.
Hematol Pathol. 6:155–160. 1992.PubMed/NCBI
|
5
|
Dimopoulos MA, Moulopoulos LA, Maniatis A
and Alexanian R: Solitary plasmacytoma of bone and asymptomatic
multiple myeloma. Blood. 96:2037–2044. 2000.PubMed/NCBI
|
6
|
Kayrouz T, Jose B, Chu AM and Scott RM:
Solitary plasmacytoma. J Surg Oncol. 24:46–48. 1983. View Article : Google Scholar : PubMed/NCBI
|
7
|
Galieni P, Cavo M, Pulsoni A, Avvisati G,
Bigazzi C, Neri S, et al: Clinical outcome of extramedullary
plasmacytoma. Haematologica. 85:47–51. 2000.PubMed/NCBI
|
8
|
Pasch W, Zhao X and Rezk SA: Solitary
plasmacytoma of the bone involving young individuals, is there a
role for preceding trauma? Int J Clin Exp Pathol. 5:463–467.
2012.PubMed/NCBI
|
9
|
Smith A, Hal H and Frauenhoffer E:
Extramedullary plasmacytoma of the pancreas: a rare entity. Case
Rep Radiol. 2012:7982642012.PubMed/NCBI
|
10
|
Kim KS, Yang HS, Park ES and Bae TH:
Solitary extramedullary plasmacytoma of the apex of arytenoid:
endoscopic, CT, and pathologic findings. Clin Exp Otorhinolaryngol.
5:107–111. 2012. View Article : Google Scholar : PubMed/NCBI
|
11
|
Jeung MY, Gangi A, Gasser B, Vasilescu C,
Massard G, Wihlm JM and Roy C: Imaging of chest wall disorders.
Radiographics. 19:617–637. 1999. View Article : Google Scholar : PubMed/NCBI
|
12
|
Thompson WM, Levy AD, Aguilera NS, Gorospe
L and Abbott RM: Angiosarcoma of the spleen: imaging
characteristics in 12 patients. Radiology. 235:106–115. 2005.
View Article : Google Scholar : PubMed/NCBI
|