Gastric tube reconstruction prevents postoperative recurrence and metastasis of esophageal cancer
- Authors:
- Runqi Zhang
- Peng Wang
- Xiaoyan Zhang
- Lei Zhang
- Chao Li
View Affiliations
Affiliations: Department of Thorax Surgery, Taian Central Hospital, Taian, Shandong 271000, P.R. China
- Published online on: February 17, 2016 https://doi.org/10.3892/ol.2016.4240
-
Pages:
2507-2509
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Esophagectomy is the main method of treating patients with esophageal cancer. Tubular stomach and whole stomach approaches may be used for esophagectomy. However, it is not known to what extent these surgical methods are associated with postoperative recurrence and metastasis. Therefore, we aimed to investigate the effect of the tubular and whole stomach approaches on postoperative recurrence and metastasis in esophageal cancer patients. One hundred and twenty‑one patients that were diagnosed with esophageal cancer by gastroscopic biopsy between March 2010 and March 2011 in Taian Central Hospital, China, were recruited into this study. There were 67 cases in the gastric tube group and 54 cases in whole stomach group. All of the patients underwent esophagectomy and there were no mortalities during surgery. All patients completed the follow‑up period. The rates of recurrence or metastasis 1 and 2 years after surgery in the gastric tube group were observed to be lower than those in the whole stomach group. The two‑year survival rates of the gastric tube group and whole stomach group were 80 and 61%, respectively. There was a significant difference in the survival rate between the two groups (P=0.016). In conclusion, this study suggests that esophageal cancer patients may gain a mid‑term benefit from gastric tube reconstruction.
View References
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
2
|
Gaur P, Kim MP and Dunkin BJ: Esophageal
cancer: recent advances in screening, targeted therapy, and
management. J Carcinog. 13:112014. View Article : Google Scholar : PubMed/NCBI
|
3
|
Shen C, Yang H, Zhang B, Chen H, Chen Z
and Chen J: Improved quality of life in patients with
adenocarcinoma of esophagogastric junction after gastric tube
reconstruction. Hepatogastroenterology. 60:1985–1989.
2013.PubMed/NCBI
|
4
|
Shu YS, Sun C, Shi WP, Shi HC, Lu SC and
Wang K: Tubular stomach or whole stomach for esophagectomy through
cervico-thoraco-abdominal approach: a comparative clinical study on
anastomotic leakage. Ir J Med Sci. 182:477–480. 2013. View Article : Google Scholar : PubMed/NCBI
|
5
|
Ge H, Liu C, Qiu R, Lu Y, Ye K, Yang C,
Liu X, Zheng X and Zhai C: The pattern of lymphatic metastasis and
influencing factors of thoracic esophageal squamous cell carcinoma.
Pract Radiat Oncol. 3(2 Suppl 1): S32–S33. 2013. View Article : Google Scholar : PubMed/NCBI
|
6
|
van de Ven C, De Leyn P, Coosemans W, Van
Raemdonck D and Lerut T: Three-field lymphadenectomy and pattern of
lymph node spread in T3 adenocarcinoma of the distal esophagus and
the gastro-esophageal junction. Eur J Cardiothorac Surg.
15:769–773. 1999. View Article : Google Scholar : PubMed/NCBI
|
7
|
Okamoto N, Ozawa S, Kitagawa Y, Shimizu Y
and Kitajima M: Metachronous gastric carcinoma from a gastric tube
after radical surgery for esophageal carcinoma. Ann Thorac Surg.
77:1189–1192. 2004. View Article : Google Scholar : PubMed/NCBI
|
8
|
Ninomiya I, Okamoto K, Oyama K, Hayashi H,
Miyashita T, Tajima H, Kitagawa H, Fushida S, Fujimura T and Ohta
T: Feasibility of esophageal reconstruction using a pedicled
jejunum with intrathoracic esophagojejunostomy in the upper
mediastinum for esophageal cancer. Gen Thorac Cardiovasc Surg.
62:627–634. 2014. View Article : Google Scholar : PubMed/NCBI
|