1
|
Luetke A, Meyers PA, Lewis I and Juergens
H: Osteosarcoma treatment - where do we stand? A state of the art
review. Cancer Treat Rev. 40:523–532. 2014. View Article : Google Scholar : PubMed/NCBI
|
2
|
Pan KL, Chan WH and Chia YY: Initial
symptoms and delayed diagnosis of osteosarcoma around the knee
joint. J Orthop Surg (Hong Kong). 18:2010. View Article : Google Scholar : PubMed/NCBI
|
3
|
Rytting M, Pearson P, Raymond AK, Ayala A,
Murray J, Yasko AW, Johnson M and Jaffe N: Osteosarcoma in
preadolescent patients. Clin Orthop Relat Res. 39–50. 2000.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Unni KK and Inwards CY: Dahlin's Bone
Tumors: General Aspects and Data on 10,165 Cases. Lippincott
Williams & Wilkins; Philadelphia: 2010
|
5
|
Ottaviani G and Jaffe N: The epidemiology
of osteosarcomaPediatric and Adolescent Osteosarcoma. Jaffe N,
Bruland OS and Bielack S: Springer; New York: pp. 3–13. 2010
|
6
|
Picci P: Osteosarcoma (Osteogenic
sarcoma). Orphanet J Rare Dis. 2:62007. View Article : Google Scholar : PubMed/NCBI
|
7
|
Savage SA, Woodson K, Walk E, Modi W, Liao
J, Douglass C, Hoover RN and Chanock SJ: National Osteosarcoma
Etiology Study Group: Analysis of genes critical for growth
regulation identifies insulin-like growth factor 2 receptor
variations with possible functional significance as risk factors
for osteosarcoma. Cancer Epidemiol Biomarkers Prev. 16:1667–1674.
2007. View Article : Google Scholar : PubMed/NCBI
|
8
|
Liu Z, Liu Q, Xu B, Wu J, Guo C, Zhu F,
Yang Q, Gao G, Gong Y and Shao C: Berberine induces p53-dependent
cell cycle arrest and apoptosis of human osteosarcoma cells by
inflicting DNA damage. Mutat Res. 662:75–83. 2009. View Article : Google Scholar : PubMed/NCBI
|
9
|
Overholtzer M, Rao PH, Favis R, Lu XY,
Elowitz MB, Barany F, Ladanyi M, Gorlick R and Levine AJ: The
presence of p53 mutations in human osteosarcomas correlates with
high levels of genomic instability. Proc Natl Acad Sci USA.
100:11547–11552. 2003. View Article : Google Scholar : PubMed/NCBI
|
10
|
Duan Z, Choy E, Harmon D, Liu X, Susa M,
Mankin H and Hornicek F: MicroRNA-199a-3p is downregulated in human
osteosarcoma and regulates cell proliferation and migration. Mol
Cancer Ther. 10:1337–1345. 2011. View Article : Google Scholar : PubMed/NCBI
|
11
|
Díaz-Montero CM, Wygant JN and McIntyre
BW: PI3-K/Akt-mediated anoikis resistance of human osteosarcoma
cells requires Src activation. Eur J Cancer. 42:1491–1500. 2006.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Cenni V, Maraldi NM, Ruggeri A, Secchiero
P, Del Coco R, De Pol A, Cocco L and Marmiroli S: Sensitization of
multidrug resistant human ostesarcoma cells to Apo2
Ligand/TRAIL-induced apoptosis by inhibition of the Akt/PKB kinase.
Int J Oncol. 25:1599–1608. 2004.PubMed/NCBI
|
13
|
Inoue R, Matsuki NA, Jing G, Kanematsu T,
Abe K and Hirata M: The inhibitory effect of alendronate, a
nitrogen-containing bisphosphonate on the PI3K-Akt-NFκB pathway in
osteosarcoma cells. Br J Pharmacol. 146:633–641. 2005. View Article : Google Scholar : PubMed/NCBI
|
14
|
Chirgwin JM and Guise TA: Molecular
mechanisms of tumor-bone interactions in osteolytic metastases. Br
J Pharmacol. 146:633–641. 2000.
|
15
|
Irizarry RA, Hobbs B, Collin F,
Beazer-Barclay YD, Antonellis KJ, Scherf U and Speed TP:
Exploration, normalization and summaries of high density
oligonucleotide array probe level data. Biostatistics. 4:249–264.
2003. View Article : Google Scholar : PubMed/NCBI
|
16
|
Bolstad BM, Irizarry RA, Åstrand M and
Speed TP: A comparison of normalization methods for high density
oligonucleotide array data based on variance and bias.
Bioinformatics. 19:185–193. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Smyth GK: Linear models and empirical
bayes methods for assessing differential expression in microarray
experiments. Stat Appl Genet Mol Biol. 3:2004.PubMed/NCBI
|
18
|
Kanehisa M and Goto S: KEGG: Kyoto
encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30.
2000. View Article : Google Scholar : PubMed/NCBI
|
19
|
Haw R, Hermjakob H, D'Eustachio P and
Stein L: Reactome pathway analysis to enrich biological discovery
in proteomics data sets. Proteomics. 11:3598–3613. 2011. View Article : Google Scholar : PubMed/NCBI
|
20
|
Harris MA, Clark J, Ireland A, Lomax J,
Ashburner M, Foulger R, Eilbeck K, Lewis S, Marshall B, Mungall C,
et al: The gene ontology (GO) database and informatics resource.
Nucleic Acids Res. 32:D258–D261. 2004. View Article : Google Scholar : PubMed/NCBI
|
21
|
da W Huang, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2008. View Article : Google Scholar
|
22
|
Dennis G Jr, Sherman BT, Hosack DA, Yang
J, Gao W, Lane HC and Lempicki RA: DAVID: Database for Annotation,
Visualization and Integrated Discovery. Genome Biol. 4:P32003.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Zhao M, Sun J and Zhao Z: TSGene: A web
resource for tumor suppressor genes. Nucleic Acids Res.
41:D970–D976. 2013. View Article : Google Scholar : PubMed/NCBI
|
24
|
Chen JS, Hung WS, Chan HH, Tsai SJ and Sun
HS: In silico identification of oncogenic potential of fyn-related
kinase in hepatocellular carcinoma. Bioinformatics. 29:420–427.
2013. View Article : Google Scholar : PubMed/NCBI
|
25
|
Szklarczyk D, Franceschini A, Kuhn M,
Simonovic M, Roth A, Minguez P, Doerks T, Stark M, Muller J, Bork
P, et al: The STRING database in 2011: functional interaction
networks of proteins, globally integrated and scored. Nucleic Acids
Res. 39:D561–D568. 2011. View Article : Google Scholar : PubMed/NCBI
|
26
|
Smoot ME, Ono K, Ruscheinski J, Wang PL
and Ideker T: Cytoscape 2.8: New features for data integration and
network visualization. Bioinformatics. 27:431–432. 2011. View Article : Google Scholar : PubMed/NCBI
|
27
|
Luo Y, Deng Z and Chen J: Pivotal
regulatory network and genes in osteosarcoma. Arch Med Sci.
9:569–575. 2013. View Article : Google Scholar : PubMed/NCBI
|
28
|
Sadikovic B, Yoshimoto M, Al-Romaih K,
Maire G, Zielenska M and Squire JA: In vitro analysis of integrated
global high-resolution DNA methylation profiling with genomic
imbalance and gene expression in osteosarcoma. PLoS One.
3:e28342008. View Article : Google Scholar : PubMed/NCBI
|
29
|
Desgrosellier JS and Cheresh DA: Integrins
in cancer: Biological implications and therapeutic opportunities.
Nat Rev Cancer. 10:9–22. 2010. View
Article : Google Scholar : PubMed/NCBI
|
30
|
Heino J and Massagué J: Transforming
growth factor-beta switches the pattern of integrins expressed in
MG-63 human osteosarcoma cells and causes a selective loss of cell
adhesion to laminin. J Biol Chem. 264:21806–21811. 1989.PubMed/NCBI
|
31
|
Adams JC and Watt FM: Changes in
keratinocyte adhesion during terminal differentiation: Reduction in
fibronectin binding precedes 51 integrin loss from the cell
surface. Cell. 63:425–435. 1990. View Article : Google Scholar : PubMed/NCBI
|
32
|
Kawashima A, Kawahara E, Tokuda R and
Nakanishi I: Tumour necrosis factor-alpha provokes upregulation of
alpha2beta1 and alpha5beta1 integrins, and cell migration in OST
osteosarcoma cells. Cell Biol Int. 25:319–329. 2001. View Article : Google Scholar : PubMed/NCBI
|
33
|
Qin L, Chen X, Wu Y, Feng Z, He T, Wang L,
Liao L and Xu J: Steroid receptor coactivator-1 upregulates
integrin α5 expression to promote breast cancer cell adhesion and
migration. Cancer Res. 71:1742–1751. 2011. View Article : Google Scholar : PubMed/NCBI
|
34
|
Duncan J, Reeves J and Cooke T: BRCA1 and
BRCA2 proteins: roles in health and disease. Mol Pathol.
51:237–247. 1998. View Article : Google Scholar : PubMed/NCBI
|
35
|
Yoshida K and Miki Y: Role of BRCA1 and
BRCA2 as regulators of DNA repair, transcription and cell cycle in
response to DNA damage. Cancer Sci. 95:866–871. 2004. View Article : Google Scholar : PubMed/NCBI
|
36
|
Yarden RI and Papa MZ: BRCA1 at the
crossroad of multiple cellular pathways: Approaches for therapeutic
interventions. Mol Cancer Ther. 5:1396–1404. 2006. View Article : Google Scholar : PubMed/NCBI
|
37
|
Deng C, Ueda E, Chen KE, Bula C, Norman
AW, Luben RA and Walker AM: Prolactin blocks nuclear translocation
of VDR by regulating its interaction with BRCA1 in osteosarcoma
cells. Mol Endocrinol. 23:226–236. 2009. View Article : Google Scholar : PubMed/NCBI
|
38
|
Harkin DP, Bean JM, Miklos D, Song YH,
Truong VB, Englert C, Christians FC, Ellisen LW, Maheswaran S,
Oliner JD and Haber DA: Induction of GADD45 and JNK/SAPK-dependent
apoptosis following inducible expression of BRCA1. Cell.
97:575–586. 1999. View Article : Google Scholar : PubMed/NCBI
|
39
|
Pao GM, Janknecht R, Ruffner H, Hunter T
and Verma IM: CBP/p300 interact with and function as
transcriptional coactivators of BRCA1. Proc Natl Acad Sci USA.
97:1020–1025. 2000. View Article : Google Scholar : PubMed/NCBI
|
40
|
Chapman MS and Verma IM: Transcriptional
activation by BRCA1. Nature. 382:678–679. 1996. View Article : Google Scholar : PubMed/NCBI
|
41
|
Monteiro AN, August A and Hanafusa H:
Evidence for a transcriptional activation function of BRCA1
C-terminal region. Proc Natl Acad Sci USA. 93:13595–13599. 1996.
View Article : Google Scholar : PubMed/NCBI
|
42
|
Ahmed H, Salama A, Salem SE and Bahnassy
AA: A case of synchronous double primary breast carcinoma and
osteosarcoma: Mismatch repair genes mutations as a possible cause
for multiple early onset malignant tumors. Am J Case Rep.
13:218–223. 2012. View Article : Google Scholar : PubMed/NCBI
|
43
|
Fujii H, Honoki K, Tsujiuchi T, Kido A,
Yoshitani K and Takakura Y: Sphere-forming stem-like cell
populations with drug resistance in human sarcoma cell lines. Int J
Oncol. 34:1381–1386. 2009.PubMed/NCBI
|
44
|
Liu B, Ma W, Jha RK and Gurung K: Cancer
stem cells in osteosarcoma: recent progress and perspective. Acta
Oncol. 50:1142–1150. 2011. View Article : Google Scholar : PubMed/NCBI
|
45
|
Wang Y, Cortez D, Yazdi P, Neff N, Elledge
SJ and Qin J: BASC, a super complex of BRCA1-associated proteins
involved in the recognition and repair of aberrant DNA structures.
Genes Dev. 14:927–939. 2000.PubMed/NCBI
|
46
|
Furlanetto RW, Harwell SE and Frick KK:
Insulin-like growth factor-I induces cyclin-D1 expression in MG63
human osteosarcoma cells in vitro. Mol Endocrinol. 8:510–517. 1994.
View Article : Google Scholar : PubMed/NCBI
|
47
|
Cai CK, Zhao GY, Tian LY, Liu L, Yan K, Ma
YL, Ji ZW, Li XX, Han K, Gao J, et al: miR-15a and miR-16-1
downregulate CCND1 and induce apoptosis and cell cycle arrest in
osteosarcoma. Oncol Rep. 28:1764–1770. 2012.PubMed/NCBI
|