Long-term remission of hormone receptor-positive/HER2-positive metastatic breast cancer due to combined treatment with everolimus/trastuzumab/exemestane: A case report

  • Authors:
    • Jian Wang
    • Chunxiao Sun
    • Xiang Huang
    • Jinrong Qiu
    • Yongmei Yin
  • View Affiliations

  • Published online on: June 6, 2017     https://doi.org/10.3892/ol.2017.6311
  • Pages: 1725-1730
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Abstract

The present case report describes a postmenopausal patient with hormone receptor (HR)+/human epidermal growth factor receptor 2 (HER2)+ metastatic breast cancer, who experienced progression of disease in bilateral lungs, lymph nodes and the liver under previous endocrine therapy and trastuzumab. Following the failure of two lines of endocrine‑based treatment, the patient was administered the combined treatment of everolimus, trastuzumab and exemestane following surgical resection of the liver metastasis. A durable partial remission was achieved, which has continued for >27 months. This prominent clinical outcome in this patient demonstrates that the combined administration of endocrine therapy, trastuzumab and everolimus is clinically effective, and may induce long‑term remission in patients with HR+/HER2+ metastatic breast cancer.
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August-2017
Volume 14 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Wang J, Sun C, Huang X, Qiu J and Yin Y: Long-term remission of hormone receptor-positive/HER2-positive metastatic breast cancer due to combined treatment with everolimus/trastuzumab/exemestane: A case report. Oncol Lett 14: 1725-1730, 2017
APA
Wang, J., Sun, C., Huang, X., Qiu, J., & Yin, Y. (2017). Long-term remission of hormone receptor-positive/HER2-positive metastatic breast cancer due to combined treatment with everolimus/trastuzumab/exemestane: A case report. Oncology Letters, 14, 1725-1730. https://doi.org/10.3892/ol.2017.6311
MLA
Wang, J., Sun, C., Huang, X., Qiu, J., Yin, Y."Long-term remission of hormone receptor-positive/HER2-positive metastatic breast cancer due to combined treatment with everolimus/trastuzumab/exemestane: A case report". Oncology Letters 14.2 (2017): 1725-1730.
Chicago
Wang, J., Sun, C., Huang, X., Qiu, J., Yin, Y."Long-term remission of hormone receptor-positive/HER2-positive metastatic breast cancer due to combined treatment with everolimus/trastuzumab/exemestane: A case report". Oncology Letters 14, no. 2 (2017): 1725-1730. https://doi.org/10.3892/ol.2017.6311