Open Access

Importance of tuberin in carcinogenesis (Review)

  • Authors:
    • Mingwei Jin
    • Qi An
    • Lei Wang
  • View Affiliations

  • Published online on: June 28, 2017     https://doi.org/10.3892/ol.2017.6490
  • Pages: 2598-2602
  • Copyright: © Jin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The cell cycle is a dynamic process with multiple phases regulating cell growth. The proper regulation is essential for avoiding errors and activation of cell death. Tumour suppressor proteins, including tuberin, are crucial in coordinating adequate cell growth and properly timed cell division. So, the present review article is focused on the latest aspects of the tuberin in the process of carcinogenesis. The PubMed was the main database used for the collection of latest data relating to multiple aspects of tuberin especially in context of cancer. Most of the recent studies revealed that mutation, truncation, and deregulation of the tuberin protein could definitely lead to cancer. Recent studies are also devoted to explore implications towards better understanding the progression of disease involving mis-regulated tuberin.
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September-2017
Volume 14 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Jin M, An Q and Wang L: Importance of tuberin in carcinogenesis (Review). Oncol Lett 14: 2598-2602, 2017.
APA
Jin, M., An, Q., & Wang, L. (2017). Importance of tuberin in carcinogenesis (Review). Oncology Letters, 14, 2598-2602. https://doi.org/10.3892/ol.2017.6490
MLA
Jin, M., An, Q., Wang, L."Importance of tuberin in carcinogenesis (Review)". Oncology Letters 14.3 (2017): 2598-2602.
Chicago
Jin, M., An, Q., Wang, L."Importance of tuberin in carcinogenesis (Review)". Oncology Letters 14, no. 3 (2017): 2598-2602. https://doi.org/10.3892/ol.2017.6490