Oncology during the COVID‑19 pandemic: challenges, dilemmas and the psychosocial impact on cancer patients (Review)
- Authors:
- Konstantinos Tsamakis
- Maria Gavriatopoulou
- Dimitrios Schizas
- Athina Stravodimou
- Aikaterini Mougkou
- Dimitrios Tsiptsios
- Vasileios Sioulas
- Eleftherios Spartalis
- Athanasios D. Sioulas
- Charalampos Tsamakis
- Nikolaos Charalampakis
- Christoph Mueller
- Donna Arya
- Paul Zarogoulidis
- Demetrios A. Spandidos
- Meletios A. Dimopoulos
- Charalabos Papageorgiou
- Emmanouil Rizos
-
Affiliations: Second Department of Psychiatry, University of Athens, ‘ATTIKON’ University Hospital, 12462 Athens, Greece, Department of Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece, First Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, 11527 Athens, Greece, Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne University Hospital, CH‑1011 Lausanne, Switzerland, Paediatric Infectious Diseases Dept, Karolinska University Hospital, 171 77 Stockholm, Sweden, Department of Neurophysiology, South Tyneside and Sunderland NHS Foundation Trust, Sunderland SR47TP, UK, Department of Gynaecologic Oncology MITERA Hospital, 15123 Athens, Greece, 2nd Department of Propaedeutic Surgery, National and Kapodistrian University of Athens School of Medicine, 11527 Athens, Greece, Gastroenterology Department, Hygeia Hospital, 15123 Athens, Greece, Department of Dermatology, Luton and Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton LU4 0DZ, UK, Department of Medical Oncology, Metaxa Cancer Hospital, Pireas, 18537 Athens, Greece, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UK, Thornford Park, Elysium Healthcare, Berkshire RG19 8ET, UK, 3rd Department of Surgery, ‘AHEPA’ University Hospital, Aristotle University of Thessaloniki, Medical School, 54621 Thessaloniki, Greece, Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece, Hematology and Medical Oncology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, 11527 Athens, Greece, First Department of Psychiatry, University of Athens, ‘Eginition’ Hospital, 11528 Athens, Greece - Published online on: May 8, 2020 https://doi.org/10.3892/ol.2020.11599
- Pages: 441-447
-
Copyright: © Tsamakis et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
Ahmad A, Mueller C and Tsamakis K: Covid-19 pandemic: A public and global mental health opportunity for social transformation? BMJ. 369:m13832020. View Article : Google Scholar : PubMed/NCBI | |
Docea AO, Tsatsakis A, Albulescu D, Cristea O, Zlatian O, Vinceti M, Moschos SA, Tsoukalas D, Goumenou M, Drakoulis N, et al: A new threat from an old enemy: Re-emergence of coronavirus (Review). Int J Mol Med. 45:1631–1643. 2020.PubMed/NCBI | |
Tsamakis K, Triantafyllis A, Tsiptsios D, Spartalis E, Mueller C, Tsamakis C, Chaidou S, Spandidos DA, Fotis L, Economou M and Rizos E: COVID 19 related stress exacerbates common physical and mental pathologies and affects treatment (Review). Exp Ther Med. (In Press). | |
Kamboj M and Sepkowitz KA: Nosocomial infections in patients with cancer. Lancet Oncol. 10:589–597. 2009. View Article : Google Scholar : PubMed/NCBI | |
Schrag D, Hershman DL and Basch E: Oncology practice during the COVID-19 pandemic. JAMA. Apr 13–2020.(Epub ahead of print). View Article : Google Scholar | |
Onder G, Rezza G and Brusaferro S: Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. Mar 23–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI | |
Wu Z and McGoogan JM: characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention. JAMA. Feb 24–2020.(Epub ahead of print). View Article : Google Scholar | |
Liang W, Guan W, Chen R, Wang W, Li J, Xu K, Li C, Ai Q, Lu W, Liang H, et al: Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China. Lancet Oncol. 21:335–337. 2020. View Article : Google Scholar : PubMed/NCBI | |
Zhang L, Zhu F, Xie L, Wang C, Wang J, Chen R, Jia P, Guan HQ, Peng L, Chen Y, et al: Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China. Ann Oncol. Mar 26–2020.(Epub ahead of print). View Article : Google Scholar | |
National Comprehensive Cancer Network (NCCN), . Principles for management of colorectal cancer patients during the COVID-19 pandemic. https://www.nccn.org/covid-19/pdf/ColorectalCOVID-19.pdfJanuary 5–2020 | |
Al-Quteimat OM and Amer AM: The impact of the COVID-19 pandemic on cancer patients. Am J Clin Oncol. Apr 16–2020.(Epub ahead of print). View Article : Google Scholar | |
The Royal College of Radiologists, . Neuro-oncology treatment guidance during COVID-19 pandemic. https://www.rcr.ac.uk/sites/default/files/neuro-oncology-treatment-covid-19.pdf?utm_medium=email&utm_source=transactionMarch 27–2020 | |
British Neuro-Oncology Society (BNOS), . Adult Neuro-Oncology Service Provision during COVID-19 outbreak. https://www.bnos.org.uk/wp-content/uploads/2020/03/Adult-neuro-oncology-service-provision-during-COVID-outbreak_SBNS-BNOS.pdfMarch 19–2020 | |
European Association of Neuro-Oncology (EANO), . COVID-19 and Neuro-oncology: considerations for daily care of brain tumor patients. EANO. (Vienna). 2020.https://www.eano.eu/ | |
Ramakrishna R, Zadeh G, Sheehan JP and Aghi MK: Inpatient and outpatient case prioritization for patients with neuro-oncologic disease amid the COVID-19 pandemic: general guidance for neuro-oncology practitioners from the AANS/CNS Tumor Section and Society for Neuro-Oncology. J Neurooncol. Apr 9–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI | |
Tsamakis K, Rizos E, Manolis JA, Chaidou S, Kympouropoulos S, Spartalis E, Spandidos DA, Tsiptsios D and Triantafyllis AS: [Comment] COVID-19 pandemic and its impact on mental health of healthcare professionals. Exp Ther Med. 19:3451–3453. 2020.PubMed/NCBI | |
Brooks SK, Webster RK, Smith LE, Woodland L, Wessely S, Greenberg N and Rubin GJ: The psychological impact of quarantine and how to reduce it: Rapid review of the evidence. Lancet. 395:912–920. 2020. View Article : Google Scholar : PubMed/NCBI | |
D'Ippolito S, Ambrosini E, Shams M, Calì G and Pastorelli D: The effect of loneliness on cancer mortality. Ann Oncol. 28:vi822017. View Article : Google Scholar | |
Hill EM and Hamm A: Intolerance of uncertainty, social support, and loneliness in relation to anxiety and depressive symptoms among women diagnosed with ovarian cancer. Psychooncology. 28:553–560. 2019. View Article : Google Scholar : PubMed/NCBI | |
Bortolato B, Hyphantis TN, Valpione S, Perini G, Maes M, Morris G, Kubera M, Köhler CA, Fernandes BS, Stubbs B, et al: Depression in cancer: The many biobehavioral pathways driving tumor progression. Cancer Treat Rev. 52:58–70. 2017. View Article : Google Scholar : PubMed/NCBI | |
Reis JC, Antoni MH and Travado L: Emotional distress, brain functioning, and biobehavioral processes in cancer patients: A neuroimaging review and future directions. CNS Spectr. 25:79–100. 2020. View Article : Google Scholar : PubMed/NCBI | |
Papanastasiou A, Seliniotaki T, Rizos E, Kampoli K, Ntavatzikos A, Arkadopoulos N, Tsionou C, Spandidos DA and Koumarianou A: Role of stress, age and adjuvant therapy in the cognitive function of patients with breast cancer. Oncol Lett. 18:507–517. 2019.PubMed/NCBI | |
Hanna TP, Evans GA and Booth CM: Cancer, COVID-19 and the precautionary principle: Prioritizing treatment during a global pandemic. Nat Rev Clin Oncol. 17:268–270. 2020. View Article : Google Scholar : PubMed/NCBI | |
Centers for Disease Control and Prevention (CDC), . Stress and Coping. Coronavirus Disease 2019 (COVID-19). https://www.cdc.gov/coronavirus/2019-ncov/daily-life-coping/managing-stress-anxiety.htmlApril 28–2020 | |
Gondal H, Choquette H, Abbas T, Le D, Chalchal HI, Iqbal N and Ahmed S: Patients and physicians' satisfaction with telemedicine (TM) in cancer care and factors that correlate with a positive patient's experience. Ann Oncol. 30:v7302019. View Article : Google Scholar | |
Sirintrapun SJ and Lopez AM: Telemedicine in cancer care. Am Soc Clin Oncol Educ Book. 38:540–545. 2018. View Article : Google Scholar : PubMed/NCBI | |
Pham C and Badowski ME: The role of telemedicine in infectious diseases. EMJ Innov. Mar 26–2019.(Epub ahead of print). | |
Cinar P, Kubal T, Freifeld A, Mishra A, Shulman L, Bachman J, Fonseca R, Uronis H, Klemanski D, Slusser K, et al: Safety at the time of the COVID-19 pandemic: How to keep our oncology patients and healthcare workers safe. J Natl Compr Canc Netw. Apr 15–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI | |
Attai DJ, Cowher MS, Al-Hamadani M, Schoger JM, Staley AC and Landercasper J: Twitter social media is an effective tool for breast cancer patient education and support: Patient-reported outcomes by survey. J Med Internet Res. 17:e1882015. View Article : Google Scholar : PubMed/NCBI | |
Shim M, Cappella JN and Han JY: How does insightful and emotional disclosure bring potential health benefits?: Study based on online support groups for women with breast cancer. J Commun. 61:432–464. 2011. View Article : Google Scholar : PubMed/NCBI | |
National Comprehensive Cancer Network (NCCN), . NCCN Best Practices Committee Infusion Efficiency Workgroup. Toolkit: Providing Oncology Treatments in the Outpatient Setting. https://www.nccn.org/about/news/ebulletin/pdf/NCCN%20OP%20Toolkit%20Final.pdfAugust. 2019 | |
American Society of Clinical Oncology (ASCO), . COVID-19 Provider & Practice Information. https://www.asco.org/asco-coronavirus-information/provider-practice-preparedness-covid-19April 28–2020 | |
American Society of Hematology, . COVID-19 Resources. https://www.hematology.org/covid-19#faqApril 28–2020 | |
Finocchiaro G: Milan 2020: COVID-19, neuro-oncology and much more. J Neurooncol. Apr 13–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI | |
Perin A, Servadei F and DiMeco F; ‘Hub; Spoke’ Lombardy Neurosurgery Group, : May we deliver neuro-oncology in difficult times (e.g. COVID-19)? J Neurooncol. Apr 10–2020.(Epub ahead of print). View Article : Google Scholar | |
Hu YJ, Zhang J and Chen Z: Experiences of practicing surgical neuro-oncology during the COVID-19 pandemic. J Neurooncol. Apr 10–2020.(Epub ahead of print). View Article : Google Scholar | |
Mohile NA, Blakeley JO, Gatson NTN, Hottinger AF, Lassman AB, Ney DE, Olar A, Schiff D, Shih HA, Strowd R, et al: Urgent considerations for the neuro-oncologic treatment of patients with gliomas during the COVID-19 pandemic. Neuro Oncol. Apr 11–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI | |
Chen W, Su XY, Wang VJ, Wang EC, Xu R, Zhong S, Sun G and Xia X: Novel Coronavirus International Public Health Emergency: Guidance on Radiation Oncology Facility Operation. Adv Radiat Oncol. Apr 1–2020.(Epub ahead of print). View Article : Google Scholar | |
Pellino G and Spinelli A: How COVID-19 outbreak is impacting colorectal cancer patients in Italy: a long shadow beyond infection. Dis Colon Rectum. Mar 17–2020.(Epub ahead of print). | |
Barbieri L, Talavera Urquijo E, Parise P, Nilsson M, Reynolds JV and Rosati R: Esophageal oncologic surgery in SARS-CoV-2 (COVID-19) emergency. Dis Esophagus. Apr 23–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI | |
Scalea JR: The distancing of surgeon from patient in the era of COVID-19: Bring on the innovation. Ann Surg. April 13–2020.(Epub ahead of print). View Article : Google Scholar | |
Qadan M, Hong TS, Tanabe KK, Ryan DP and Lillemoe KD: A multidisciplinary team approach for triage of elective cancer surgery at the Massachusetts General Hospital during the novel Coronavirus COVID-19 outbreak. Ann Surg. April 13–2020.(Epub ahead of print). View Article : Google Scholar | |
Yu GY, Lou Z and Zhang W: Several suggestions of operation for colorectal cancer under the outbreak of coronavirus disease 2019 in China. Zhonghua Wei Chang Wai Ke Za Zhi. 23:208–211. 2020.(In Chinese). PubMed/NCBI | |
Yu J, Ouyang W, Chua MLK and Xie C: SARS-CoV-2 transmission in patients with cancer at a Tertiary Care Hospital in Wuhan, China. JAMA Oncol. Mar 25–2020.(Epub ahead of print). View Article : Google Scholar | |
Bernheim A, Mei X, Huang M, Yang Y, Fayad ZA, Zhang N, Diao K, Lin B, Zhu X, Li K, et al: Chest CT findings in coronavirus disease-19 (COVID-19): Relationship to duration of infection. Radiology. 200463:2004632020. View Article : Google Scholar | |
Remon J, Passiglia F, Ahn MJ, Barlesi F, Forde PM, Garon EB, Gettinger S, Goldberg SB, Herbst RS, Horn L, et al: Immune checkpoint inhibitors in thoracic malignancies: review of the existing evidence by an IASLC expert panel and recommendations. J Thorac Oncol. Mar 14–2020.(Epub ahead of print). View Article : Google Scholar | |
Delaunay M, Prévot G, Collot S, Guilleminault L, Didier A and Mazières J: Management of pulmonary toxicity associated with immune checkpoint inhibitors. Eur Respir Rev. 28:1900122019. View Article : Google Scholar : PubMed/NCBI | |
Abbas O, Miller DD and Bhawan J: Cutaneous malignant melanoma: Update on diagnostic and prognostic biomarkers. Am J Dermatopathol. 36:363–379. 2014. View Article : Google Scholar : PubMed/NCBI | |
Conforti C, Giuffrida R, Di Meo N and Zalaudek I: Management of advanced melanoma in the COVID-19 era. Dermatol Ther. Apr 22–2020.(Epub ahead of print). View Article : Google Scholar | |
AIM at Melanoma Foundation, . Melanoma Survivorship In the Age of COVID-19. https://www.youtube.com/watch?v=tulUC9fG09EApri 23–2020 | |
Melanoma UK: Melanoma UK COVID-19 Community Support Group. https://www.melanomauk.org.uk/melanoma-uk-covid-19-community-support-group | |
Ramirez PT, Chiva L, Eriksson AGZ, Frumovitz M, Fagotti A, Gonzalez Martin A, Jhingran A and Pareja R: COVID-19 global pandemic: Options for management of gynecologic gancers. Int J Gynecol Cancer. doi: 10.1136/ijgc-2020-001419. | |
Society for Gynecologic Oncology (SGO), . Surgical considerations for gynecologic oncologists during the COVID-19 pandemic. https://www.sgo.org/clinical-practice/management/March 27–2020 | |
AAGL-Elevating Gynecologic Surgery, . COVID-19: Joint Statement on Minimally Invasive Gynecologic Surgery. https://www.aagl.org/news/covid-19-joint-statement-on-minimally-invasive-gynecologic-surgery/March 27–2020 | |
Pothuri B, Secord AA, Armstrong DK, Chan J, Fader AN, Huh W, Kesterson J, Liu JF, Moore K, Westin SN and Naumann RW: Anti-cancer therapy and clinical trial considerations for gynecologic oncology patients during the COVID-19 pandemic crisis. Gynecol Oncol. (In Press). | |
European Society of Gynaecological Oncology (ESGO), . ESGO Covid-19 Updates. https://www.esgo.org/esgo-covid-19-communication/ | |
American College of Surgeons, . COVID-19: Guidance for Triage of Non-Emergent Surgical Procedures. https://www.facs.org/covid-19/clinical-guidance/triageMarch 17–2020 | |
Downar J and Seccareccia D; Associated Medical Services Inc. Educational Fellows in Care at the End of Life, : Palliating a pandemic: ‘all patients must be cared for’. J Pain Symptom Manage. 39:291–295. 2010. View Article : Google Scholar : PubMed/NCBI | |
Salako O, Okunade K, Allsop M, Habeebu M, Toye M, Oluyede G, Fagbenro G and Salako B: Upheaval in cancer care during the COVID-19 outbreak. Ecancermedicalscience. 14:ed972020. View Article : Google Scholar : PubMed/NCBI | |
Chen AY: Ethical Framework for Head and Neck Endocrine Surgery in the COVID 19 pandemic. Authorea. doi:10.22541/au.158775702.25904845. | |
Givi B, Schiff BA, Chinn SB, Clayburgh D, Iyer NG, Jalisi S, Moore MG, Nathan CA, Orloff LA, O'Neill JP, et al: Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic. JAMA Otolaryngol Neck Surg. Mar 31–2020.(Epub ahead of print). View Article : Google Scholar | |
Spartalis E, Moris D and Tomos P: Sternal metastasis as first presentation of a well-differentiated papillary thyroid carcinoma. Surgery. 162:1336–1337. 2017. View Article : Google Scholar : PubMed/NCBI | |
Spartalis ED, Karatzas T, Charalampoudis P, Vergadis C and Dimitroulis D: Neglected papillary thyroid carcinoma seven years after initial diagnosis. Case Rep Oncol Med. 2013:1489732013.PubMed/NCBI | |
Damaskos C, Garmpis N, Valsami S, Spartalis E, Antoniou EA, Tomos P, Karamaroudis S, Zoumpou T, Pergialiotis V, Stergios K, et al: Histone deacetylase inhibitors: A novel therapeutic weapon against medullary thyroid cancer? Anticancer Res. 36:5019–5024. 2016. View Article : Google Scholar : PubMed/NCBI | |
Bouffet E, Challinor J, Sullivan M, Biondi A, Rodriguez-Galindo C and Pritchard-Jones K: Early advice on managing children with cancer during the COVID-19 pandemic and a call for sharing experiences. Pediatr Blood Cancer. Apr 2–2020.(Epub ahead of print). View Article : Google Scholar | |
Hrusak O, Kalina T, Wolf J, Balduzzi A, Provenzi M, Rizzari C, Rives S, Del Pozo Carlavilla M, Alonso MEV, Domínguez-Pinilla N, et al: Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment. Eur J Cancer. 132:11–16. 2020. View Article : Google Scholar : PubMed/NCBI | |
Casanova M, Pagani Bagliacca E, Silva M, Patriarca C, Veneroni L, Clerici CA, Spreafico F, Luksch R, Terenziani M, Meazza C, et al: How young patients with cancer perceive the COVID-19 (coronavirus) epidemic in Milan, Italy: Is there room for other fears? Pediatr Blood Cancer. Apr 2–2020.(Epub ahead of print). View Article : Google Scholar | |
Simon A, Ammann RA, Bode U, Fleischhack G, Wenchel HM, Schwamborn D, Gravou C, Schlegel PG, Rutkowski S, Dannenberg C, et al: Healthcare-associated infections in pediatric cancer patients: Results of a prospective surveillance study from university hospitals in Germany and Switzerland. BMC Infect Dis. 8:702008. View Article : Google Scholar : PubMed/NCBI | |
Kouni S, Kourlaba G, Mougkou K, Maroudi S, Chavela B, Nteli C, Lourida A, Spyridis N, Zaoutis T and Coffin S: Assessment of hand hygiene resources and practices at the 2 children's hospitals in Greece. Pediatr Infect Dis J. 33:e247–e251. 2014. View Article : Google Scholar : PubMed/NCBI | |
Dietz JR, Moran MS, Isakoff SJ, Kurtzman SH, Willey SC, Burstein HJ, Bleicher RJ, Lyons JA, Sarantou T, Baron PL, et al: Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. the COVID-19 pandemic breast cancer consortium. Breast Cancer Res Treat. Apr 24–2020.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI |