1
|
Bednarek AK, Laflin KJ, Daniel RL, Liao Q,
Hawkins KA and Aldaz CM: WWOX, a novel WW domain-containing protein
mapping to human chromosome 16q23.3-24.1, a region frequently
affected in breast cancer. Cancer Res. 60:2140–2145.
2000.PubMed/NCBI
|
2
|
Ried K, Finnis M, Hobson L, et al: Common
chromosomal fragile site FRA16D sequence: identification of the FOR
gene spanning FRA16D and homozygous deletions and translocation
breakpoints in cancer cells. Hum Mol Genet. 9:1651–1663. 2000.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Del Mare S, Salah Z and Aqeilan RI: WWOX:
Its genomics, partners, and functions. J Cell Biochem. 108:737–745.
2009.PubMed/NCBI
|
4
|
Macias MJ, Wiesner S and Sudol M: WW and
SH3 domains, two different scaffolds to recognize proline-rich
ligands. FEBS Lett. 513:30–37. 2002. View Article : Google Scholar : PubMed/NCBI
|
5
|
Wang X, Chao L, Jin G, Ma G, Zang Y and
Sun J: Association between CpG island methylation of the WWOX gene
and its expression in breast cancers. Tumour Biol. 30:8–14. 2009.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Guo W, Wang G, Dong Y, Guo Y, Kuang G and
Dong Z: Decreased expression of WWOX in the development of
esophageal squamous cell carcinoma. Mol Carcinog. Dec 27–2011.(Epub
ahead of print). View
Article : Google Scholar
|
7
|
Nakayama S, Semba S, Maeda N, Matsushita
M, Kuroda Y and Yokozaki H: Hypermethylation-mediated reduction of
WWOX expression in intraductal papillary mucinous neoplasms of the
pancreas. Br J Cancer. 100:1438–1443. 2009. View Article : Google Scholar : PubMed/NCBI
|
8
|
Dias EP, Pimenta FJ, Sarquis MS, et al:
Association between decreased WWOX protein expression and thyroid
cancer development. Thyroid. 17:1055–1059. 2007. View Article : Google Scholar : PubMed/NCBI
|
9
|
Yang J, Cogdell D, Yang D, et al: Deletion
of the WWOX gene and frequent loss of its protein expression in
human osteosarcoma. Cancer Lett. 291:31–38. 2010. View Article : Google Scholar : PubMed/NCBI
|
10
|
Fabbri M, Iliopoulos D, Trapasso F, et al:
WWOX gene restoration prevents lung cancer growth in vitro and in
vivo. Proc Natl Acad Sci USA. 102:15611–15616. 2005. View Article : Google Scholar : PubMed/NCBI
|
11
|
Iliopoulos D, Fabbri M, Druck T, Qin HR,
Han SY and Huebner K: Inhibition of breast cancer cell growth in
vitro and in vivo: effect of restoration of Wwox expression. Clin
Cancer Res. 13:268–274. 2007. View Article : Google Scholar : PubMed/NCBI
|
12
|
Aqeilan RI, Hagan JP, Aqeilan HA,
Pichiorri F, Fong Ly and Croce CM: Inactivation of the WWOX Gene
accelerates forestomach tumor progression in vivo. Cancer Res.
67:5606–5610. 2007. View Article : Google Scholar : PubMed/NCBI
|
13
|
Aqeilan RI, Trapasso F, Hussain S, et al:
Targeted deletion of Wwox reveals a tumor suppressor function. Proc
Natl Acad Sci USA. 104:3949–3954. 2007. View Article : Google Scholar : PubMed/NCBI
|
14
|
Ishii H, Vecchione A, Furukawa Y, et al:
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic
malignancies. Mol Cancer Res. 1:940–947. 2003.PubMed/NCBI
|
15
|
Ishii H and Furukawa Y: Alterations of
common chromosome fragile sites in hematopoietic malignancies. Int
J Hematol. 79:238–242. 2004. View Article : Google Scholar : PubMed/NCBI
|
16
|
Yang JL and Zhang W: WWOX tumor suppressor
gene. Histol Histopathol. 23:877–882. 2008.
|
17
|
Zhang P, Jia R, Ying L, Liu B, Qian G, Fan
X and Ge S: WWOX-mediated apoptosis in A549 cells mainly involves
the mitochondrial pathway. Mol Med Rep. 6:121–124. 2012.PubMed/NCBI
|
18
|
Chang NS: A potential role of p53 and WOX1
in mitochondrial apoptosis (review). Int J Mol Med. 9:19–24.
2002.PubMed/NCBI
|
19
|
Kosla K, Pluciennik E, Kurzyk A,
Jesionek-Kupnicka D, Kordek R, Potemski P and Bednarek AK:
Molecular analysis of WWOX expression correlation with
proliferation and apoptosis in glioblastoma multiforme. J
Neurooncol. 101:207–213. 2011. View Article : Google Scholar : PubMed/NCBI
|
20
|
Zhou YL, Xu YJ and Zhang ZX: A study on
expression changes of a tumor suppressor WWOX in human lung
adenocarcinoma cell line A549. China Oncology. 15:234–237.
2005.
|
21
|
Wang XF and He YL: Construction of a
lentiviral vector carrying human bcl-2 gene and its expression in
human ovarian granulosa cells. Nan Fang Yi Ke Da Xue Xue Bao.
28:1856–1859. 2008.(In Chinese).
|
22
|
Reagan-Shaw S, Nihal M, Ahsan H, Mukhtar H
and Ahmad N: Combination of vitamin E and selenium causes an
induction of apoptosis of human prostate cancer cells by enhancing
Bax/Bcl-2 ratio. Prostate. 68:1624–1634. 2008. View Article : Google Scholar : PubMed/NCBI
|
23
|
Iliopoulos D, Guler G, Han SY, et al:
Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in
lung, breast and bladder cancer. Oncogene. 24:1625–1633. 2005.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Hu BS, Tan JW, Zhu GH, Wang DF, Zhou X and
Sun ZQ: WWOX induces apoptosis and inhibits proliferation of human
hepatoma cell line SMMC-7721. World J Gastroenterol. 18:3020–3026.
2012. View Article : Google Scholar : PubMed/NCBI
|
25
|
Bednarek AK, Keck-Waggoner CL, Daniel RL,
et al: WWOX, the FRA16D gene, behaves as a suppressor of tumor
growth. Cancer Res. 61:8068–8073. 2001.PubMed/NCBI
|
26
|
Gourley C, Paige AJ, Taylor KJ, et al:
WWOX gene expression abolishes ovarian cancer tumorigenicity in
vivo and decreases attachment to fibronectin via integrin alpha3.
Cancer Res. 69:4835–4842. 2009. View Article : Google Scholar : PubMed/NCBI
|
27
|
Xiong Z, Hu S and Wang Z: Cloning of WWOX
gene and its growth-inhibiting effects on ovarian cancer cells. J
Huazhong Univ Sci Technolog Med Sci. 30:365–369. 2010. View Article : Google Scholar : PubMed/NCBI
|
28
|
Qin HR, Iliopoulos D, Semba S, et al: A
Role for the WWOX gene in prostate cancer. Cancer Res.
66:6477–6480. 2006. View Article : Google Scholar : PubMed/NCBI
|
29
|
Watanabe A, Hippo Y, Taniguchi H, et al:
An opposing view on WWOX protein function as a tumor suppressor.
Cancer Res. 63:8629–8633. 2003.PubMed/NCBI
|