New insights into the mechanism of F-box proteins in colorectal cancer (Review)

  • Authors:
    • Jian Gong
    • Jirong Huo
  • View Affiliations

  • Published online on: February 27, 2015     https://doi.org/10.3892/or.2015.3823
  • Pages: 2113-2120
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Abstract

Colorectal cancer (CRC) is one of the most common cancers worldwide with a high incidence and mortality rate. Integrative studies including systematic sequencing of colorectal tumors have provided an unprecedented insight into the molecular basis of CRC. Recently, evidence indicates that F-box proteins (FBPs) play a critical role in the oncogenesis, invasion, metastasis and prognostic assessment of CRC. Therefore, this review discusses the recent literature regarding the function and regulation of FBPs in the pathogenesis of CRC. Furthermore, we highlight that FBPs may represent an attractive therapeutic target for CRC.
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May-2015
Volume 33 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Gong J and Huo J: New insights into the mechanism of F-box proteins in colorectal cancer (Review). Oncol Rep 33: 2113-2120, 2015.
APA
Gong, J., & Huo, J. (2015). New insights into the mechanism of F-box proteins in colorectal cancer (Review). Oncology Reports, 33, 2113-2120. https://doi.org/10.3892/or.2015.3823
MLA
Gong, J., Huo, J."New insights into the mechanism of F-box proteins in colorectal cancer (Review)". Oncology Reports 33.5 (2015): 2113-2120.
Chicago
Gong, J., Huo, J."New insights into the mechanism of F-box proteins in colorectal cancer (Review)". Oncology Reports 33, no. 5 (2015): 2113-2120. https://doi.org/10.3892/or.2015.3823