Nutritional status of patients with ovarian cancer and associated factors

Nguyen,Thanh-Lam; Vu‑Thi,Hue; Do,Nam-Khanh; Nguyen‑Thi,Thanh-Hoa; Pham‑Van,Binh; Chu,Dinh-Toi

doi:10.3892/wasj.2023.213

Nutritional status of patients with ovarian cancer and associated factors

Authors:
- Thanh-Lam Nguyen
- Hue Vu‑Thi
- Nam-Khanh Do
- Thanh-Hoa Nguyen‑Thi
- Binh Pham‑Van
- Dinh-Toi Chu
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Affiliations: Center for Biomedicine and Community Health, International School, Vietnam National University - Hanoi, Hanoi 100000, Vietnam, Center for Biomedicine and Community Health, International School, Vietnam National University - Hanoi, Hanoi 100000, Vietnam, Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam, Vietnam National Cancer Hospital, Hanoi 100000, Vietnam
Published online on: November 13, 2023 https://doi.org/10.3892/wasj.2023.213
Article Number: 36
Copyright : © Nguyen et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Malnutrition associated with cancer is a common concern and negatively affects the resilience of patients. The method of assessing nutrition based on serum blood albumin levels is considered to be an objective one. However, due to the long half‑life, specificity is also controversial. The present study cross‑sectional study was conducted to assess the nutritional status of patients with ovarian cancer (OC) assessed according to the serum albumin levels of from 2018 to 2021. For this purpose, the medical records of 129 patients with OC were selected. As a result, the malnutrition rate by serum albumin accounted for 17.1%. The rate of malnutrition in patients with OC at stages III and IV (35.9%), was almost 5‑fold higher than that of patients with OC at stages I and II (7.9%). At the time of testing, post‑operative malnutrition accounted for 56.2%, >2‑fold higher than the pre‑operative malnutrition rate. Subclinical indicators, including the numbers of red blood cells, hematocrit and hemoglobin levels, neutrophil percentage, lymphocyte percentage, neutrophil, lymphocyte, monocyte and platelet counts, glucose and creatinine levels, Na⁺, K⁺, Cl^‑ and total calcium levels were found to be significantly associated with the changes in nutritional status according to serum albumin levels. On the whole, the findings of the present study may assist healthcare professionals to improve the nutritional status of patients, and also suggests the possible use of serum albumin in assessing the nutritional status.

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