Open Access

Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review

  • Authors:
    • Eko Agus Subagio
    • Galih Indra Permana
    • Abdul Hafid Bajamal
    • Muhammad Faris
    • Nur Setiawan Suroto
    • Amaliya Rasyida
    • Budi Utomo
  • View Affiliations

  • Published online on: November 14, 2023     https://doi.org/10.3892/wasj.2023.214
  • Article Number: 37
  • Copyright : © Subagio et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

The best artificial disc material must closely resemble the viscoelasticity, biomechanics and bioavailability of a natural human intervertebral disc. Currently, there is a lack of reviews discussing the characterization of polyvinyl alcohol (PVA) hydrogel as a nucleus pulposus (NP) replacement in intervertebral disc herniation. The present study systematically reviewed the biomechanical characterization of PVA hydrogel as a potential ideal candidate for the replacement of NP. The PubMed, Google Scholar, Science Direct, and Cochrane Database of Systematic Reviews databases were searched according to the Preferred Reporting Items for Systematic Reviews and Meta‑Analyses guideline. Data from the literature regarding study design, sample size, materials and biomechanical properties were collected. The literature search identified seven publications, which were read to obtain information about the biomechanical characteristics of PVA hydrogel material used with different compounds. Stress, strain and Young's modulus testing outcomes were all evaluated. The biomechanical characteristics of the materials were evaluated to determine how closely they resemble those of the NP. The results revealed that the PVA hydrogel and NP share similar biomechanical characteristics. In order to enhance its biomechanical capabilities, the PVA hydrogel may be combined with other materials.
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November-December 2023
Volume 5 Issue 6

Print ISSN: 2632-2900
Online ISSN:2632-2919

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Spandidos Publications style
Subagio EA, Permana GI, Bajamal AH, Faris M, Suroto NS, Rasyida A and Utomo B: Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review. World Acad Sci J 5: 37, 2023
APA
Subagio, E.A., Permana, G.I., Bajamal, A.H., Faris, M., Suroto, N.S., Rasyida, A., & Utomo, B. (2023). Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review. World Academy of Sciences Journal, 5, 37. https://doi.org/10.3892/wasj.2023.214
MLA
Subagio, E. A., Permana, G. I., Bajamal, A. H., Faris, M., Suroto, N. S., Rasyida, A., Utomo, B."Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review". World Academy of Sciences Journal 5.6 (2023): 37.
Chicago
Subagio, E. A., Permana, G. I., Bajamal, A. H., Faris, M., Suroto, N. S., Rasyida, A., Utomo, B."Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review". World Academy of Sciences Journal 5, no. 6 (2023): 37. https://doi.org/10.3892/wasj.2023.214