Malnutrition and micronutrient deficiency following gastrointestinal cancer surgery: A case report and mini‑review of the literature
- Authors:
- Thanh Tat Do
- Phuong Lan Thi Pham
- Phuong Thi Nguyen
- Anh Gia Pham
- Ha Ngoc Vu
View Affiliations
Affiliations: Department of Colorectal and Perineal Surgery, Viet Duc University Hospital, Hanoi 100000, Vietnam, Department of Nutrition, Viet Duc University Hospital, Hanoi 100000, Vietnam, Department of Nutrition, Tam Anh General Hospital, Hanoi 100000, Vietnam, Department of Oncology, Viet Duc University Hospital, Hanoi 100000, Vietnam, Department of Nutrition and Dietetics, Hanoi Medical University Hospital, Hanoi Medical University, Hanoi 100000, Vietnam
- Published online on: July 15, 2024 https://doi.org/10.3892/wasj.2024.266
-
Article Number:
51
-
Copyright : © Do
et al. This is an open access article distributed under the
terms of Creative
Commons Attribution License [CC BY 4.0].
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Malnutrition is a common issue following gastrointestinal cancer surgery, negatively affecting the quality of life and clinical outcomes of patients following surgery. However, this issue is often overlooked, and limited data are available on the long‑term effectiveness of nutritional intervention. The present study describes the case of a female patient developing severe malnutrition and micronutrient deficiencies following a gastrectomy for stomach cancer and a pancreaticoduodenectomy due to tumor recurrence. The patient received comprehensive nutrition intervention, combining both oral feeding and supplemental parenteral nutrition, oral and intravenous multi micronutrients supplements and personalized pancreatic enzyme replacement therapy. Her clinical condition markedly improved, as well as the edema caused by malnutrition and cutaneous lesions caused by micronutrient deficiency. Gastrectomy and pancreaticoduodenectomy are both major surgeries that severely affect the nutritional status of patients, as these are the main digestive organs of the body, particularly in the background of cancer and more adverse events from chemotherapy treatment. Progressive protein‑energy malnutrition and micronutrient deficiencies are the results of decreased dietary intake, anatomical changes and malabsorption following gastrointestinal surgery. Thus, surgeons/clinicians should consider the comprehensive treatment of patients, including comprehensive nutritional care before, during and following surgery in order to prevent malnutrition and its complications. This would also enhance the effectiveness of surgery and the long‑term clinical results following surgery for patients with cancer.
View References
|
1
|
Barker LA, Gout BS and Crowe TC: Hospital
malnutrition: Prevalence, identification and impact on patients and
the healthcare system. Int J Environ Res Public Health. 8:514–527.
2011.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Corish CA and Kennedy NP: Protein-energy
undernutrition in hospital in-patients. Br J Nutr. 83:575–591.
2000.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Tisdale MJ: Cachexia in cancer patients.
Nat Rev Cancer. 2:862–871. 2002.PubMed/NCBI View
Article : Google Scholar
|
|
4
|
Saunders J and Smith T: Malnutrition:
Causes and consequences. Clin Med (Lond). 10:624–627.
2010.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Norman K, Haß U and Pirlich M:
Malnutrition in older adults-recent advances and remaining
challenges. Nutrients. 13(2764)2021.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Altomare DF and Rotelli MT (eds):
Nutritional support after gastrointestinal surgery. Cham: Springer
International Publishing, 2019.
|
|
7
|
Struyvenberg MR, Martin CR and Freedman
SD: Practical guide to exocrine pancreatic insufficiency-breaking
the myths. BMC Med. 15(29)2017.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Ghaneh P and Neoptolemos JP: Exocrine
pancreatic function following pancreatectomy. Ann N Y Acad Sci.
880:308–318. 1999.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Lee AHH and Ward SM: Pancreatic exocrine
insufficiency after total gastrectomy-a systematic review. J
Pancreas. 20:130–137. 2019.
|
|
10
|
Gilliland TM, Villafane-Ferriol N, Shah
KP, Shah RM, Tran Cao HS, Massarweh NN, Silberfein EJ, Choi EA, Hsu
C, McElhany AL, et al: Nutritional and metabolic derangements in
pancreatic cancer and pancreatic resection. Nutrientsc.
9(243)2017.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Capurso G, Traini M, Piciucchi M,
Signoretti M and Arcidiacono PG: Exocrine pancreatic insufficiency:
Prevalence, diagnosis, and management. Clin Exp Gastroenterol.
12:129–139. 2019.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Hoffman M, Micheletti RG and Shields BE:
Nutritional dermatoses in the hospitalized patient. Cutis 105: 296,
302-308.E1-E5, 2020.
|
|
13
|
Carabotti M, Annibale B and Lahner E:
Common pitfalls in the management of patients with micronutrient
deficiency: Keep in mind the stomach. Nutrients.
13(208)2021.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Yu HH, Yang TM, Shan YS and Lin PW: Zinc
deficiency in patients undergoing pancreatoduodenectomy for
periampullary tumors is associated with pancreatic exocrine
insufficiency. World J Surg. 35:2110–2117. 2011.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Jun JH, Yoo JE, Lee JA, Kim YS, Sunwoo S,
Kim BS and Yook JH: Anemia after gastrectomy in long-term survivors
of gastric cancer: A retrospective cohort study. Int J Surg.
28:162–168. 2016.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Bechara N, Flood VM and Gunton JE: A
systematic review on the role of vitamin C in tissue healing.
Antioxidants (Basel). 11(1605)2022.PubMed/NCBI View Article : Google Scholar
|
