Open Access

Athlegenetics: Athletic characteristics and musculoskeletal conditions (Review)

  • Authors:
    • Nikolaos Panagiotou
    • Alexis Sagonas
    • Effie Salata
    • Thanos Fotis
    • Eleni Ntoumou
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  • Published online on: March 12, 2025     https://doi.org/10.3892/wasj.2025.332
  • Article Number: 44
  • Copyright : © Panagiotou et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Innovative elite athlete evaluation can now incorporate novel genetic profiling strategies alongside traditional biochemical and modern ergophysiological monitoring. This genotype‑empowered approach aims to broadly assess the performance capabilities, risk of injury and recovery needs of elite athletes, in orer to effectively reach maximum performance, as well as to achieve successful longevity in the sport. An analysis of the genetic makeup of an athlete delves into specific genetic variations linked to athletic performance, injury susceptibility, musculoskeletal conditions and recovery requirements, thus facilitating personalized training strategies and interventions to maximize the potential of an athlete. Genetic testing can also be combined with a series of diverse traditional and novel phenotypic evaluations, including ergophysiological assessment, biochemical testing, metabolomics profiling, micronutrient analysis, echocardiography and burnout testing, among others, to produce a multidimensional understanding of the health of an athlete. The present review discusses this athlegenetics strategy in an aim to pave the way for personalized interventions in training, nutrition and supplementation, for injury prevention, faster recovery and mental well‑being support. This scientific approach holds significant promise for enhancing athletic performance and the longevity of an athlete in their associated sport, through evidence‑based, personalized interventions that advance sports performance optimization.
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May-June 2025
Volume 7 Issue 3

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Copy and paste a formatted citation
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Spandidos Publications style
Panagiotou N, Sagonas A, Salata E, Fotis T and Ntoumou E: Athlegenetics: Athletic characteristics and musculoskeletal conditions (Review). World Acad Sci J 7: 44, 2025.
APA
Panagiotou, N., Sagonas, A., Salata, E., Fotis, T., & Ntoumou, E. (2025). Athlegenetics: Athletic characteristics and musculoskeletal conditions (Review). World Academy of Sciences Journal, 7, 44. https://doi.org/10.3892/wasj.2025.332
MLA
Panagiotou, N., Sagonas, A., Salata, E., Fotis, T., Ntoumou, E."Athlegenetics: Athletic characteristics and musculoskeletal conditions (Review)". World Academy of Sciences Journal 7.3 (2025): 44.
Chicago
Panagiotou, N., Sagonas, A., Salata, E., Fotis, T., Ntoumou, E."Athlegenetics: Athletic characteristics and musculoskeletal conditions (Review)". World Academy of Sciences Journal 7, no. 3 (2025): 44. https://doi.org/10.3892/wasj.2025.332