Targeting Cancer-Associated Fibroblasts: Novel Approaches and Future Directions

Cancer-associated fibroblasts (CAFs) have emerged as key players in cancer progression and therapy resistance, making them an attractive target for cancer treatment. However, to stand out from similar previous research, we aim to focus on the latest advances in CAF-targeted therapies that have direct implications for drug development, including preclinical in vivo data and combination therapies with cancer immunotherapy. In addition, we will explore the potential of novel molecular targets and cell-based therapies to enrich the scope of CAF-targeted research. This special issue will feature original research articles, reviews, and perspectives on the topic.

13/03/2025