Open Access

Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report

  • Authors:
    • Chang-Zhen Lei
    • Dao-Jun Gong
    • Yang-Fan Zhou
  • View Affiliations

  • Published online on: December 14, 2022     https://doi.org/10.3892/etm.2022.11770
  • Article Number: 71
  • Copyright: © Lei et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

White cord syndrome refers to an emerging neurological dysfunction occurring after spinal decompression surgery with hyperenhancing changes on T2‑weighted magnetic resonance imaging (T2WI). The pathophysiological mechanism is hypothesized to be an ischemia‑reperfusion injury following chronic ischemic spinal cord decompression. A 54‑year‑old man was admitted to Jinhua Municipal Central Hospital with complaints of numbness and weakness in the extremities and swelling in the neck. MRI showed degeneration and herniation of the C4‑C7 intervertebral discs. The patient underwent anterior cervical corpectomy and fusion (ACCF). On the 7th postoperative day, the patient reappeared with weakness of the limbs. Physical examination revealed paralysis. Emergency MRI suggested T2 high signal myelopathy and emergency surgery was performed following the diagnosis of white cord syndrome. Following the operation, the patient's neurological system gradually improved. The motor ability and sensory function of the extremities recovered at 7‑month follow‑up. Spine surgeons should be aware of this serious complication. The present case serves to provide experience for clinical treatment and diagnosis and encourage research into its pathophysiology.
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January-2023
Volume 25 Issue 1

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Spandidos Publications style
Lei C, Gong D and Zhou Y: Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report. Exp Ther Med 25: 71, 2023.
APA
Lei, C., Gong, D., & Zhou, Y. (2023). Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report. Experimental and Therapeutic Medicine, 25, 71. https://doi.org/10.3892/etm.2022.11770
MLA
Lei, C., Gong, D., Zhou, Y."Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report". Experimental and Therapeutic Medicine 25.1 (2023): 71.
Chicago
Lei, C., Gong, D., Zhou, Y."Late‑onset white cord syndrome following anterior cervical discectomy and fusion: A case report". Experimental and Therapeutic Medicine 25, no. 1 (2023): 71. https://doi.org/10.3892/etm.2022.11770