Identification and characterization of ankyrin repeat and SOCS box-containing gene ASB15 in silico

  • Authors:
    • Kenichi Yoshida
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  • Published online on: August 1, 2005     https://doi.org/10.3892/ijmm.16.2.343
  • Pages: 343-347
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Abstract

The ASBs are a family of ankyrin-repeat proteins that contain a C-terminal SOCS box motif, which was first identified in the suppressor of cytokine signaling (SOCS) proteins. Here, we identified the ASB15 gene by using bio-informatics. Human ASB15 gene, consisting of 12 exons, was located within human genome sequences RP11-390E23 (AC006333.3). Complete coding sequence of human ASB15 cDNA was determined by FLJ43370 cDNA (AK125360), which was identified by using partial coding sequence of human ASB15 cDNA (AF403033) as a query. Human, chimpanzee, bovine, canine, and murine ASB15 showed 88-99% total-amino acid identity. N-terminal and central seven ankyrin repeats, and C-terminal SOCS box were identified within ASB15 protein.

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August 2005
Volume 16 Issue 2

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Yoshida K: Identification and characterization of ankyrin repeat and SOCS box-containing gene ASB15 in silico. Int J Mol Med 16: 343-347, 2005.
APA
Yoshida, K. (2005). Identification and characterization of ankyrin repeat and SOCS box-containing gene ASB15 in silico. International Journal of Molecular Medicine, 16, 343-347. https://doi.org/10.3892/ijmm.16.2.343
MLA
Yoshida, K."Identification and characterization of ankyrin repeat and SOCS box-containing gene ASB15 in silico". International Journal of Molecular Medicine 16.2 (2005): 343-347.
Chicago
Yoshida, K."Identification and characterization of ankyrin repeat and SOCS box-containing gene ASB15 in silico". International Journal of Molecular Medicine 16, no. 2 (2005): 343-347. https://doi.org/10.3892/ijmm.16.2.343