Open Access

Current strategies for nonalcoholic fatty liver disease treatment (Review)

  • Authors:
    • Jing Sun
    • Xiuli Jin
    • Yiling Li
  • View Affiliations

  • Published online on: August 8, 2024     https://doi.org/10.3892/ijmm.2024.5412
  • Article Number: 88
  • Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Nonalcoholic fatty liver disease (NAFLD), the most common chronic hepatic disease, has become a leading health problem worldwide. The present review summarized the methods and mechanisms to treat NAFLD, including the Mediterranean diet, physical activity and exercise, bariatric surgery and specific therapeutic agents, including statins, peroxisome proliferator‑activated receptor agonists, cenicriviroc and farnesoid X receptor agonists. Biologically active substances, such as peptides, alkaloids, polyphenolic compounds, silymarin, antibiotics, fatty acids, vitamins, probiotics, synbiotics and lamiaceae have also demonstrated actions that combat NAFLD. Considering their different mechanisms of action, combining some of them may prove an efficacious treatment for NAFLD. In this light, the present review describes recent progress and future prospects in treating NAFLD.
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October-2024
Volume 54 Issue 4

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Copy and paste a formatted citation
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Spandidos Publications style
Sun J, Jin X and Li Y: Current strategies for nonalcoholic fatty liver disease treatment (Review). Int J Mol Med 54: 88, 2024.
APA
Sun, J., Jin, X., & Li, Y. (2024). Current strategies for nonalcoholic fatty liver disease treatment (Review). International Journal of Molecular Medicine, 54, 88. https://doi.org/10.3892/ijmm.2024.5412
MLA
Sun, J., Jin, X., Li, Y."Current strategies for nonalcoholic fatty liver disease treatment (Review)". International Journal of Molecular Medicine 54.4 (2024): 88.
Chicago
Sun, J., Jin, X., Li, Y."Current strategies for nonalcoholic fatty liver disease treatment (Review)". International Journal of Molecular Medicine 54, no. 4 (2024): 88. https://doi.org/10.3892/ijmm.2024.5412