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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Oct 1999 Volume 4 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
Oct 1999 Volume 4 Issue 4

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Article

Vascular retardation in dormant growth-stunted malignant melanomas.

  • Authors:
    • C Piérard-Franchimont
    • F Henry
    • O Heymans
    • G E Piérard

  • View Affiliations / Copyright

    Affiliations: Department of Dermatopathology, University Medical Center Sart Tilman, B-4000 Liège, Belgium.
  • Pages: 403-409
    |
    Published online on: October 1, 1999
       https://doi.org/10.3892/ijmm.4.4.403
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Abstract

Progression and metastatic spread of primary cutaneous melanoma (PCM) is largely predicted by the thickness of the primary tumor. However, the accretive or proliferative pattern of growth of PCM is another aspect that might affect the prognosis. We retrieved from our histopathological files 11 superficial spreading PCM which had been documented to show an almost stable size for at least 3 years before excision. The area of the PCM at the skin surface had been measured by planimetry on the excision specimens. Histological sections were used to measure the maximum thickness of the neoplasms. A PCM volume estimate was derived by multiplying the surface area by the thickness of the tumors. In addition, the vessel area was determined beneath and outside the PCM lateral margins on Ulex europaeus agglutinin-1-stained sections using computer-assisted image analysis. Peritumoral vascularity was significantly more developed than at distance of the neoplasms. A significant negative exponential correlation was yielded between the peritumoral vascularity and the PCM volume estimate. Such vascular eclipse might be the cause of clinical PCM dormancy. However, other possible independent mechanisms are not ruled out by the present study.

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Copy and paste a formatted citation
Spandidos Publications style
Piérard-Franchimont C, Henry F, Heymans O and Piérard G: Vascular retardation in dormant growth-stunted malignant melanomas.. Int J Mol Med 4: 403-409, 1999.
APA
Piérard-Franchimont, C., Henry, F., Heymans, O., & Piérard, G. (1999). Vascular retardation in dormant growth-stunted malignant melanomas.. International Journal of Molecular Medicine, 4, 403-409. https://doi.org/10.3892/ijmm.4.4.403
MLA
Piérard-Franchimont, C., Henry, F., Heymans, O., Piérard, G."Vascular retardation in dormant growth-stunted malignant melanomas.". International Journal of Molecular Medicine 4.4 (1999): 403-409.
Chicago
Piérard-Franchimont, C., Henry, F., Heymans, O., Piérard, G."Vascular retardation in dormant growth-stunted malignant melanomas.". International Journal of Molecular Medicine 4, no. 4 (1999): 403-409. https://doi.org/10.3892/ijmm.4.4.403
Copy and paste a formatted citation
x
Spandidos Publications style
Piérard-Franchimont C, Henry F, Heymans O and Piérard G: Vascular retardation in dormant growth-stunted malignant melanomas.. Int J Mol Med 4: 403-409, 1999.
APA
Piérard-Franchimont, C., Henry, F., Heymans, O., & Piérard, G. (1999). Vascular retardation in dormant growth-stunted malignant melanomas.. International Journal of Molecular Medicine, 4, 403-409. https://doi.org/10.3892/ijmm.4.4.403
MLA
Piérard-Franchimont, C., Henry, F., Heymans, O., Piérard, G."Vascular retardation in dormant growth-stunted malignant melanomas.". International Journal of Molecular Medicine 4.4 (1999): 403-409.
Chicago
Piérard-Franchimont, C., Henry, F., Heymans, O., Piérard, G."Vascular retardation in dormant growth-stunted malignant melanomas.". International Journal of Molecular Medicine 4, no. 4 (1999): 403-409. https://doi.org/10.3892/ijmm.4.4.403
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