search button
Open Access

Connexin40 nonsense mutation in familial atrial fibrillation

  • Authors:
    • Yi-Qing Yang
    • Xian-Ling Zhang
    • Xin-Hua Wang
    • Hong-Wei Tan
    • Hai-Feng Shi
    • Wei-Feng Jiang
    • Wei-Yi Fang
    • Xu Liu

  • View Affiliations

  • Published online on: October 1, 2010     https://doi.org/10.3892/ijmm_00000505
  • Pages: 605-610
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with substantial morbidity and mortality. Genetic variants play important roles in the pathogenesis of AF. However, AF is a genetically heterogeneous disorder, and the genetic determinants in most patients with AF remain to be identified. In this study, the entire coding region of the connexin40 gene, encoding the cardiac gap junction membrane channel protein α5, was sequenced in 126 unrelated probands with familial AF. A novel heterozygous mutation, c.145C

Related Articles

Journal Cover

October 2010
Volume 26 Issue 4

Print ISSN: 1107-3756
Online ISSN:1791-244X

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 5.7
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 12.3
  • CiteScore Rank: Q1: #28/347 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 1.022
  • SCImago Journal Rank (SJR): 1.167
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
Yang Y, Zhang X, Wang X, Tan H, Shi H, Jiang W, Fang W and Liu X: Connexin40 nonsense mutation in familial atrial fibrillation . Int J Mol Med 26: 605-610, 2010.
APA
Yang, Y., Zhang, X., Wang, X., Tan, H., Shi, H., Jiang, W. ... Liu, X. (2010). Connexin40 nonsense mutation in familial atrial fibrillation . International Journal of Molecular Medicine, 26, 605-610. https://doi.org/10.3892/ijmm_00000505
MLA
Yang, Y., Zhang, X., Wang, X., Tan, H., Shi, H., Jiang, W., Fang, W., Liu, X."Connexin40 nonsense mutation in familial atrial fibrillation ". International Journal of Molecular Medicine 26.4 (2010): 605-610.
Chicago
Yang, Y., Zhang, X., Wang, X., Tan, H., Shi, H., Jiang, W., Fang, W., Liu, X."Connexin40 nonsense mutation in familial atrial fibrillation ". International Journal of Molecular Medicine 26, no. 4 (2010): 605-610. https://doi.org/10.3892/ijmm_00000505