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Glutathione S-transferases and cancer (Review)

  • Authors:
    • D Schipper
    • M Wagenmans
    • D Wagener
    • W Peters

  • View Affiliations

  • Published online on: June 1, 1997     https://doi.org/10.3892/ijo.10.6.1261
  • Pages: 1261-1264
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Cytosolic glutathione S-transferases are a family of enzymes involved in the metabolism of drugs, toxins, carcinogens and also of anticancer drugs. Recent studies have indicated that glutathione S-transferases (GSTs) may play an important role in the resistance of cells to toxins and carcinogens but also to anticancer drugs. This report reviews the current literature concerning the role of glutathione S-transferases in anticancer drug resistance. Moreover, the significance of GST pi in carcinogenesis and its role as prognostic factor is discussed.

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June 1997
Volume 10 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Journal Metrics
  • Impact Factor: 4.5
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 9.6
  • CiteScore Rank: Q1: #66/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
Schipper D, Wagenmans M, Wagener D and Peters W: Glutathione S-transferases and cancer (Review). Int J Oncol 10: 1261-1264, 1997.
APA
Schipper, D., Wagenmans, M., Wagener, D., & Peters, W. (1997). Glutathione S-transferases and cancer (Review). International Journal of Oncology, 10, 1261-1264. https://doi.org/10.3892/ijo.10.6.1261
MLA
Schipper, D., Wagenmans, M., Wagener, D., Peters, W."Glutathione S-transferases and cancer (Review)". International Journal of Oncology 10.6 (1997): 1261-1264.
Chicago
Schipper, D., Wagenmans, M., Wagener, D., Peters, W."Glutathione S-transferases and cancer (Review)". International Journal of Oncology 10, no. 6 (1997): 1261-1264. https://doi.org/10.3892/ijo.10.6.1261