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Genetic predisposition and specific chromosomal defects associated with Sinclair swine malignant melanomas

  • Authors:
    • S Pathak
    • M Amoss

  • View Affiliations

  • Published online on: July 1, 1997     https://doi.org/10.3892/ijo.11.1.53
  • Pages: 53-57
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Abstract

Cytogenetic abnormalities are the hallmarks of most cancers and cutaneous melanomas are no exception. The purpose of this study was to determine whether nonrandom chromosomal abnormalities are associated with development and spontaneous regression of congenital cutaneous melanoma in Sinclair miniature swine. Careful analyses of the peripheral blood lymphocytes, skin fibroblasts, and melanoma cell lines of Sinclair swine indicated telomeric association, genetic instability, and clonal marker formations involving swine chromosomes 2, 3, 6, 7, 12, and 17.

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July 1997
Volume 11 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Journal Metrics
  • Impact Factor: 4.5
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 9.6
  • CiteScore Rank: Q1: #66/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
Pathak S and Amoss M: Genetic predisposition and specific chromosomal defects associated with Sinclair swine malignant melanomas. Int J Oncol 11: 53-57, 1997.
APA
Pathak, S., & Amoss, M. (1997). Genetic predisposition and specific chromosomal defects associated with Sinclair swine malignant melanomas. International Journal of Oncology, 11, 53-57. https://doi.org/10.3892/ijo.11.1.53
MLA
Pathak, S., Amoss, M."Genetic predisposition and specific chromosomal defects associated with Sinclair swine malignant melanomas". International Journal of Oncology 11.1 (1997): 53-57.
Chicago
Pathak, S., Amoss, M."Genetic predisposition and specific chromosomal defects associated with Sinclair swine malignant melanomas". International Journal of Oncology 11, no. 1 (1997): 53-57. https://doi.org/10.3892/ijo.11.1.53