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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Jun 1998 Volume 12 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Jun 1998 Volume 12 Issue 6

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Article

HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).

  • Authors:
    • Y Yonemitsu
    • E W Alton
    • K Komori
    • T Yoshizumi
    • K Sugimachi
    • Y Kaneda

  • View Affiliations / Copyright

    Affiliations: Ion Transport Unit, National Heart and Lung Institute, Imperial College School of Medicine, Emmanuel Kaye Building, London SW3 6LR, UK.
  • Pages: 1277-1362
    |
    Published online on: June 1, 1998
       https://doi.org/10.3892/ijo.12.6.1277
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Abstract

Haemagglutinating virus of Japan (HVJ; Sendai virus), a member of the mouse paramyxovirus family, has been combined with liposomes to produce a novel gene transfer system, namely HVJ liposomes. This vector system is defined as a , constructed with inactivated viral particles and non-viral (artificial) multi- or unilamellar liposomes containing gene expression cassettes and has several advantages in comparison with other viral or non-viral systems. Many studies have shown that this vector system can, not only produce efficient gene transfer using reporter genes, but also with resulting in vivo functional changes in several animal models of diseases. Despite these results, it is likely that the construct will need to be modified to improve gene transfer and expression efficiency and also to extend the potential disease targets. We review the present status of this hybrid vector system and also discuss possible modifications for future application to either in vivo analysis of specific gene expression or human gene therapy strategies for congenital or acquired diseases.

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Copy and paste a formatted citation
Spandidos Publications style
Yonemitsu Y, Alton E, Komori K, Yoshizumi T, Sugimachi K and Kaneda Y: HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).. Int J Oncol 12: 1277-1362, 1998.
APA
Yonemitsu, Y., Alton, E., Komori, K., Yoshizumi, T., Sugimachi, K., & Kaneda, Y. (1998). HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).. International Journal of Oncology, 12, 1277-1362. https://doi.org/10.3892/ijo.12.6.1277
MLA
Yonemitsu, Y., Alton, E., Komori, K., Yoshizumi, T., Sugimachi, K., Kaneda, Y."HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).". International Journal of Oncology 12.6 (1998): 1277-1362.
Chicago
Yonemitsu, Y., Alton, E., Komori, K., Yoshizumi, T., Sugimachi, K., Kaneda, Y."HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).". International Journal of Oncology 12, no. 6 (1998): 1277-1362. https://doi.org/10.3892/ijo.12.6.1277
Copy and paste a formatted citation
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Spandidos Publications style
Yonemitsu Y, Alton E, Komori K, Yoshizumi T, Sugimachi K and Kaneda Y: HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).. Int J Oncol 12: 1277-1362, 1998.
APA
Yonemitsu, Y., Alton, E., Komori, K., Yoshizumi, T., Sugimachi, K., & Kaneda, Y. (1998). HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).. International Journal of Oncology, 12, 1277-1362. https://doi.org/10.3892/ijo.12.6.1277
MLA
Yonemitsu, Y., Alton, E., Komori, K., Yoshizumi, T., Sugimachi, K., Kaneda, Y."HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).". International Journal of Oncology 12.6 (1998): 1277-1362.
Chicago
Yonemitsu, Y., Alton, E., Komori, K., Yoshizumi, T., Sugimachi, K., Kaneda, Y."HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (review).". International Journal of Oncology 12, no. 6 (1998): 1277-1362. https://doi.org/10.3892/ijo.12.6.1277
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