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Stabilization of disease as a useful predictor of survival following second-line chemotherapy in small cell lung cancer and ovarian cancer patients.

  • Authors:
    • A Cesano
    • S R Lane
    • R Poulin
    • G Ross
    • S Z Fields

  • View Affiliations

  • Published online on: December 1, 1999     https://doi.org/10.3892/ijo.15.6.1233
  • Pages: 1233-1241
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Abstract

To assess the value of disease stabilization (SD) as a predictor of survival following chemotherapy, data were analyzed from multicenter clinical trials in small cell lung cancer (SCLC) and ovarian cancer (OC) patients receiving various second-line chemotherapy regimens. In both patient populations, SD (lasting >8 weeks) and partial responses (PR) were associated with a survival benefit versus progressive disease (PD); interestingly, the survival benefit was similar between the two groups (PR and SD). These results suggest that, at least in these populations, SD may represent a potential benefit of chemotherapy and therefore the distinction between SD and PR may not be useful.

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Journal Cover

Dec 1999
Volume 15 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Journal Metrics
  • Impact Factor: 4.5
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 9.6
  • CiteScore Rank: Q1: #66/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
Cesano A, Lane S, Poulin R, Ross G and Fields S: Stabilization of disease as a useful predictor of survival following second-line chemotherapy in small cell lung cancer and ovarian cancer patients.. Int J Oncol 15: 1233-1241, 1999.
APA
Cesano, A., Lane, S., Poulin, R., Ross, G., & Fields, S. (1999). Stabilization of disease as a useful predictor of survival following second-line chemotherapy in small cell lung cancer and ovarian cancer patients.. International Journal of Oncology, 15, 1233-1241. https://doi.org/10.3892/ijo.15.6.1233
MLA
Cesano, A., Lane, S., Poulin, R., Ross, G., Fields, S."Stabilization of disease as a useful predictor of survival following second-line chemotherapy in small cell lung cancer and ovarian cancer patients.". International Journal of Oncology 15.6 (1999): 1233-1241.
Chicago
Cesano, A., Lane, S., Poulin, R., Ross, G., Fields, S."Stabilization of disease as a useful predictor of survival following second-line chemotherapy in small cell lung cancer and ovarian cancer patients.". International Journal of Oncology 15, no. 6 (1999): 1233-1241. https://doi.org/10.3892/ijo.15.6.1233