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EXPRESSION OF PS2 AND CATHEPSIN-D IN BREAST-CANCER

  • Authors:
    • JL CAZIN
    • P GOSSELIN
    • B BONIFACE
    • M BONIFACE
    • A DEMAILLE

  • View Affiliations

  • Published online on: June 1, 1993     https://doi.org/10.3892/ijo.2.6.1081
  • Pages: 1081-1084
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Abstract

Cytosolic levels of pS2 and Cathepsin D (Cath D) were compared in 145 primary breast cancer patients using the immunoradiometric (IRMA) assays ELSA-pS2-degrees and ELSA-Cath. D-degrees of Cis biointernational. The mean values were 20.04 +/- 41.75 ng pS2/mg of cytosol protein (cp) and 49.94 +/- 33.71 pmol Cath D/mg cp. The pS2 level was significantly associated with Estrogen Receptor (ER), Progesterone Receptor (PgR) and Cath D levels. Significant associations were also found between Log (pS2) or Log (Cath. D) and differentiation grade (SBR), between Log (pS2) and ER (+,-) or PgR (+,-), between Log (Cath. D) and PgR (+,-). No correlations were noted between Log (pS2) or Log (Cath D) and menopausal status, tumor size (T) and lymph node involvement (N), between pS2 and age, between Cath D and age, ER and PgR, between Log (Cath D) and ER (+,-). Contrary to Cath D, pS2 was strongly linked to steroid receptors.

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Journal Cover

June 1993
Volume 2 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
CAZIN J, GOSSELIN P, BONIFACE B, BONIFACE M and DEMAILLE A: EXPRESSION OF PS2 AND CATHEPSIN-D IN BREAST-CANCER. Int J Oncol 2: 1081-1084, 1993.
APA
CAZIN, J., GOSSELIN, P., BONIFACE, B., BONIFACE, M., & DEMAILLE, A. (1993). EXPRESSION OF PS2 AND CATHEPSIN-D IN BREAST-CANCER. International Journal of Oncology, 2, 1081-1084. https://doi.org/10.3892/ijo.2.6.1081
MLA
CAZIN, J., GOSSELIN, P., BONIFACE, B., BONIFACE, M., DEMAILLE, A."EXPRESSION OF PS2 AND CATHEPSIN-D IN BREAST-CANCER". International Journal of Oncology 2.6 (1993): 1081-1084.
Chicago
CAZIN, J., GOSSELIN, P., BONIFACE, B., BONIFACE, M., DEMAILLE, A."EXPRESSION OF PS2 AND CATHEPSIN-D IN BREAST-CANCER". International Journal of Oncology 2, no. 6 (1993): 1081-1084. https://doi.org/10.3892/ijo.2.6.1081