Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm

  • Authors:
    • Kazutaka Kurokohchi
    • Shunichi Hirai
    • Tomohiro Ohgi
    • Masahiro Ono
    • Akira Yoshitake
    • Kazuo Ebara
    • Yasuhiro Kitamura
    • Yoshitaka Kasai
    • Tsuyoshi Maeta
    • Takaaki Kiuchi
    • Tsutomu Masaki
    • Hirohito Yoneyama
    • Fumikazu Kohi
    • Shigeki Kuriyama
  • View Affiliations

  • Published online on: August 1, 2006     https://doi.org/10.3892/ijo.29.2.375
  • Pages: 375-380
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Abstract

We previously reported that the combination therapy of percutaneous ethanol injection and radiofrequency ablation (PEI-RFA) was more effective than RFA alone in inducing wider coagulated necrosis for the treatment of hepatocellular carcinoma (HCC). In the present study, we thoracoscopically applied the combination therapy to the treatment of HCC located immediately under the diaphragm. RFA electrode and ethanol injection needle were inserted into the tumor through the right side of the diaphragm in 6 patients with HCC close to the diaphragm. In all cases, the tumor was completely ablated with enough safety margin around the tumor. No local tumor recurrence has been observed in a relatively short-time follow-up period. The volume of coagulated necrosis and the energy requirement for coagulation in thoracoscopic ethanol injection and RFA (T-EI-RFA) were comparable to those of PEI-RFA. Although HCC located immediately under the diaphragm is difficult to treat with a percutaneous approach due to the poor visualization by ultrasonography, T-EI-RFA is considered to be an effective treatment modality.

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August 2006
Volume 29 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Kurokohchi K, Hirai S, Ohgi T, Ono M, Yoshitake A, Ebara K, Kitamura Y, Kasai Y, Maeta T, Kiuchi T, Kiuchi T, et al: Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm. Int J Oncol 29: 375-380, 2006.
APA
Kurokohchi, K., Hirai, S., Ohgi, T., Ono, M., Yoshitake, A., Ebara, K. ... Kuriyama, S. (2006). Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm. International Journal of Oncology, 29, 375-380. https://doi.org/10.3892/ijo.29.2.375
MLA
Kurokohchi, K., Hirai, S., Ohgi, T., Ono, M., Yoshitake, A., Ebara, K., Kitamura, Y., Kasai, Y., Maeta, T., Kiuchi, T., Masaki, T., Yoneyama, H., Kohi, F., Kuriyama, S."Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm". International Journal of Oncology 29.2 (2006): 375-380.
Chicago
Kurokohchi, K., Hirai, S., Ohgi, T., Ono, M., Yoshitake, A., Ebara, K., Kitamura, Y., Kasai, Y., Maeta, T., Kiuchi, T., Masaki, T., Yoneyama, H., Kohi, F., Kuriyama, S."Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm". International Journal of Oncology 29, no. 2 (2006): 375-380. https://doi.org/10.3892/ijo.29.2.375