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CRITERIA FOR ASSESSING THE NEUROENDOCRINE PHENOTYPE AND ITS INCIDENCE IN NONSMALL CELL LUNG CANCERS

  • Authors:
    • HE BURNETT
    • AV SPEDDING
    • N PENDLETON
    • WE KENYON
    • C WALKER

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  • Published online on: July 1, 1993     https://doi.org/10.3892/ijo.3.1.65
  • Pages: 65-69
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Abstract

The neuroendocrine (NE) characteristics of 26 resected non-small cell lung cancers (NSCLC) were determined using immunocytochemistry. All 26 tumours expressed some features of NE differentiation, but the percentage of NE-positive tumours varied when the criteria for positivity, such as minimum staining intensity and proportion of stained cells, were adjusted. The incidence of NE-NSCLC was higher in these tumours (up to 100%) compared to that found by other groups when using their criteria for NE positivity, suggesting a genuinely higher incidence of NE-NSCLC in this geographical region. NE phenotype in these tumours did not correlate with survival.

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July 1993
Volume 3 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Impact Factor: 4.5
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  • CiteScore: 9.6
  • CiteScore Rank: Q1: #66/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
BURNETT H, SPEDDING A, PENDLETON N, KENYON W and WALKER C: CRITERIA FOR ASSESSING THE NEUROENDOCRINE PHENOTYPE AND ITS INCIDENCE IN NONSMALL CELL LUNG CANCERS. Int J Oncol 3: 65-69, 1993.
APA
BURNETT, H., SPEDDING, A., PENDLETON, N., KENYON, W., & WALKER, C. (1993). CRITERIA FOR ASSESSING THE NEUROENDOCRINE PHENOTYPE AND ITS INCIDENCE IN NONSMALL CELL LUNG CANCERS. International Journal of Oncology, 3, 65-69. https://doi.org/10.3892/ijo.3.1.65
MLA
BURNETT, H., SPEDDING, A., PENDLETON, N., KENYON, W., WALKER, C."CRITERIA FOR ASSESSING THE NEUROENDOCRINE PHENOTYPE AND ITS INCIDENCE IN NONSMALL CELL LUNG CANCERS". International Journal of Oncology 3.1 (1993): 65-69.
Chicago
BURNETT, H., SPEDDING, A., PENDLETON, N., KENYON, W., WALKER, C."CRITERIA FOR ASSESSING THE NEUROENDOCRINE PHENOTYPE AND ITS INCIDENCE IN NONSMALL CELL LUNG CANCERS". International Journal of Oncology 3, no. 1 (1993): 65-69. https://doi.org/10.3892/ijo.3.1.65