Advances in intravesical therapy for the treatment of non‑muscle invasive bladder cancer (Review)

  • Authors:
    • Michael D. Weintraub
    • Qingdi Quentin Li
    • Piyush K. Agarwal
  • View Affiliations

  • Published online on: June 12, 2014     https://doi.org/10.3892/mco.2014.314
  • Pages: 656-660
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Abstract

The knowledge of tumor biology and the biomechanical properties of the urothelium have led to significant advances in the development of intravesical therapy for the treatment of non‑muscle invasive bladder cancer (NMIBC). Targeted therapy improves the efficacy and decreases the side effects of antineoplastic agents. Nanoparticles that target antitumor agents to the urothelial cells have allowed for improved delivery of these agents to tumor cells. Gene therapy is another strategy that has allowed for a targeted induction of an antitumor response. Finally, engineering of the bacillus Calmette‑Guérin (BCG) vaccine aimed to minimize the potential side effects associated with this treatment. These novel approaches hold promise for decreasing the rate of progression and recurrence of NMIBC.
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September-October 2014
Volume 2 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Copy and paste a formatted citation
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Spandidos Publications style
Weintraub MD, Li QQ and Agarwal PK: Advances in intravesical therapy for the treatment of non‑muscle invasive bladder cancer (Review). Mol Clin Oncol 2: 656-660, 2014.
APA
Weintraub, M.D., Li, Q.Q., & Agarwal, P.K. (2014). Advances in intravesical therapy for the treatment of non‑muscle invasive bladder cancer (Review). Molecular and Clinical Oncology, 2, 656-660. https://doi.org/10.3892/mco.2014.314
MLA
Weintraub, M. D., Li, Q. Q., Agarwal, P. K."Advances in intravesical therapy for the treatment of non‑muscle invasive bladder cancer (Review)". Molecular and Clinical Oncology 2.5 (2014): 656-660.
Chicago
Weintraub, M. D., Li, Q. Q., Agarwal, P. K."Advances in intravesical therapy for the treatment of non‑muscle invasive bladder cancer (Review)". Molecular and Clinical Oncology 2, no. 5 (2014): 656-660. https://doi.org/10.3892/mco.2014.314