1
|
Mueller EL, Sabbatini A, Gebremariam A,
Mody R, Sung L and Macy ML: Why pediatric patients with cancer
visit the emergency department: United States, 2006-2010. Pediatr
Blood Cancer. 62:490–495. 2015.PubMed/NCBI View Article : Google Scholar
|
2
|
Azoulay E, Mokart D, Pène F, Lambert J,
Kouatchet A, Mayaux J, Vincent F, Nyunga M, Bruneel F, Laisne LM,
et al: Outcomes of critically ill patients with hematologic
malignancies: Prospective multicenter data from France and
Belgium-a groupe de recherche respiratoire en réanimation
onco-hématologique study. J Clin Oncol. 31:2810–2818.
2013.PubMed/NCBI View Article : Google Scholar
|
3
|
Soares M, Bozza FA, Azevedo LC, Silva UV,
Corrêa TD, Colombari F, Torelly AP, Varaschin P, Viana WN, Knibel
MF, et al: Effects of organizational characteristics on outcomes
and resource use in patients with cancer admitted to intensive care
units. J Clin Oncol. 34:3315–3324. 2016.PubMed/NCBI View Article : Google Scholar
|
4
|
Avilés-Robles M, Schnur JJ,
Dorantes-Acosta E, Márquez-González H, Ocampo-Ramírez LA and Chawla
NV: Predictors of septic shock or bacteremia in children
experiencing febrile neutropenia post-chemotherapy. J Pediatric
Infect Dis Soc. 11:498–503. 2022.PubMed/NCBI View Article : Google Scholar
|
5
|
Castelán-Martínez OD, Palomo-Colli MA,
Barrios-López VE, Silva-Jivaja KM, Juárez-Villegas LE,
Castañeda-Hernández G and Sánchez-Rodríguez MA: Efficacy and safety
of oral magnesium supplementation in reducing febrile neutropenia
episodes in children with solid tumors treated with cisplatin-based
chemotherapy: Randomized clinical trial. Cancer Chemother
Pharmacol. 86:673–679. 2020.PubMed/NCBI View Article : Google Scholar
|
6
|
Phillips B: Prospective cohort study of
the predictive value of inflammatory biomarkers over clinical
variables in children and young people with cancer presenting with
fever and neutropenia. F1000Res. 10(1070)2021.PubMed/NCBI View Article : Google Scholar
|
7
|
Charoenngam N and Holick MF: Immunologic
effects of vitamin D on human health and disease. Nutrients.
12(2097)2020.PubMed/NCBI View Article : Google Scholar
|
8
|
Xiao D, Zhang X, Ying J, Zhou Y, Li X, Mu
D and Qu Y: Association between vitamin D status and sepsis in
children: A meta-analysis of observational studies. Clin Nutr.
39:1735–1741. 2020.PubMed/NCBI View Article : Google Scholar
|
9
|
de Haan K, Groeneveld ABJ, de Geus HRH,
Egal M and Struijs A: Vitamin D deficiency as a risk factor for
infection, sepsis and mortality in the critically ill: Systematic
review and meta-analysis. Crit Care. 18(660)2014.PubMed/NCBI View Article : Google Scholar
|
10
|
Nguyen HB, Eshete B, Lau KHW, Sai A,
Villarin M and Baylink D: Serum 1,25-dihydroxyvitamin D: An outcome
prognosticator in human sepsis. PLoS One. 8(e64348)2013.PubMed/NCBI View Article : Google Scholar
|
11
|
Liu PT, Stenger S, Li H, Wenzel L, Tan BH,
Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, et al: Toll-like
receptor triggering of a vitamin D-mediated human antimicrobial
response. Science. 311:1770–1773. 2006.PubMed/NCBI View Article : Google Scholar
|
12
|
Thennarasu S, Tan A, Penumatchu R,
Shelburne CE, Heyl DL and Ramamoorthy A: Antimicrobial and membrane
disrupting activities of a peptide derived from the human
cathelicidin antimicrobial peptide LL37. Biophys J. 98:248–257.
2010.PubMed/NCBI View Article : Google Scholar
|
13
|
Henzler Wildman KA, Lee DK and Ramamoorthy
A: Mechanism of lipid bilayer disruption by the human antimicrobial
peptide, LL-37. Biochemistry. 42:6545–6558. 2003.PubMed/NCBI View Article : Google Scholar
|
14
|
U.S. Department of Health and Human
Services: Common Terminology Criteria for Adverse Events (CTCAE)
Version 5.0., 2017.
|
15
|
Bodey GP, Buckley M, Sathe YS and
Freireich EJ: Quantitative relationships between circulating
leukocytes and infection in patients with acute leukemia. Ann
Intern Med. 64:328–340. 1966.PubMed/NCBI View Article : Google Scholar
|
16
|
Munns C, Zacharin MR, Rodda CP, Batch JA,
Morley R, Cranswick NE, Craig ME, Cutfield WS, Hofman PL, Taylor
BJ, et al: Prevention and treatment of infant and childhood vitamin
D deficiency in Australia and New Zealand: A consensus statement;
Prevention and treatment of infant and childhood vitamin D
deficiency in Australia and New Zealand: A consensus statement. Med
J Aust. 185:268–272. 2006.PubMed/NCBI View Article : Google Scholar
|
17
|
Holick MF: Medical progress vitamin D
deficiency. N Engl J Med. 357:266–281. 2007.
|
18
|
Castelán-Martínez OD, Rodríguez-Islas F,
Vargas-Neri JL, Palomo-Colli MA, López-Aguilar E, Clark P,
Castañeda-Hernández G and Rivas-Ruiz R: Risk factors for febrile
neutropenia in children with solid tumors treated with
cisplatin-based chemotherapy. J Pediatr Hematol Oncol. 38:191–196.
2016.PubMed/NCBI View Article : Google Scholar
|
19
|
Bothra M, Seth R, Kapil A, Dwivedi SN,
Bhatnagar S and Xess I: Evaluation of predictors of adverse outcome
in febrile neutropenic episodes in pediatric oncology patients.
Indian J Pediatr. 80:297–302. 2013.PubMed/NCBI View Article : Google Scholar
|
20
|
Santolaya ME, Alvarez AM, Avilés CL,
Becker A, Mosso C, O'Ryan M, Payá E, Salgado C, Silva P, Topelberg
S, et al: Admission clinical and laboratory factors associated with
death in children with cancer during a febrile neutropenic episode.
Pediatr Infect Dis J. 26:794–798. 2007.PubMed/NCBI View Article : Google Scholar
|
21
|
Erbaş İC, Çakıl Güzin A, Özdem Alataş Ş,
Karaoğlu Asrak H, Akans İ, Akyol Ş, Özlü C, Tüfekçi Ö, Yılmaz Ş,
Ören H and Belet N: Etiology and factors affecting severe
complications and mortality of febrile neutropenia in children with
acute leukemia. Turk J Haematol. 40:143–153. 2023.PubMed/NCBI View Article : Google Scholar
|
22
|
Das A, Trehan A and Bansal D: Risk factors
for microbiologically-documented infections, mortality and
prolonged hospital stay in children with febrile neutropenia.
Indian Pediatr. 55:859–864. 2018.PubMed/NCBI
|
23
|
Gupta S, Bonilla M, Gamero M, Fuentes SL,
Caniza M and Sung L: Microbiology and mortality of pediatric
febrile neutropenia in El Salvador. J Pediatr Hematol Oncol.
33:276–280. 2011.PubMed/NCBI View Article : Google Scholar
|
24
|
Hancock REW, Haney EF and Gill EE: The
immunology of host defence peptides: Beyond antimicrobial activity.
Nat Rev Immunol. 16:321–334. 2016.PubMed/NCBI View Article : Google Scholar
|
25
|
Sørensen O, Arnljots K, Cowland JB,
Bainton DF and Borregaard N: The human antibacterial cathelicidin,
hCAP-18, is synthesized in myelocytes and metamyelocytes and
localized to specific granules in neutrophils. Blood. 90:2796–2803.
1997.PubMed/NCBI
|
26
|
Park K, Elias PM, Oda Y, Mackenzie D,
Mauro T, Holleran WM and Uchida Y: Regulation of cathelicidin
antimicrobial peptide expression by an endoplasmic reticulum (ER)
stress signaling, vitamin d receptor-independent pathway. J Biol
Chem. 286:34121–34130. 2011.PubMed/NCBI View Article : Google Scholar
|
27
|
Cirioni O, Ghiselli R, Tomasinsig L,
Orlando F, Silvestri C, Skerlavaj B, Riva A, Rocchi M, Saba V,
Zanetti M, et al: Efficacy of LL-37 and granulocyte
colony-stimulating factor in a neutropenic murine sepsis due to
pseudomonas aeruginosa. Shock. 30:443–448. 2008.PubMed/NCBI View Article : Google Scholar
|
28
|
Mansbach JM, Hasegawa K, Ajami NJ,
Petrosino JF, Piedra PA, Tierney CN, Espinola JA and Camargo CA:
Serum LL-37 levels associated with severity of bronchiolitis and
viral etiology. Clin Infect Dis. 65:967–975. 2017.PubMed/NCBI View Article : Google Scholar
|
29
|
Suberviola B, Lavin BA, Jimenez AF,
Perez-San Martin S, Garcia-Unzueta M and Santibañez M: Vitamin D
binding protein, but not vitamin D or vitamin D-related peptides,
is associated with septic shock mortality. Enferm Infecc Microbiol
Clin (Engl Ed). 37:239–243. 2019.PubMed/NCBI View Article : Google Scholar
|
30
|
Barbeiro DF, Barbeiro HV, Zampieri FG,
César Machado MC, Torggler Filho F, Gomes Cunha DM, Goulart AC,
Velasco IT, Monteiro da Cruz Neto L, Possolo de Souza H and
Pinheiro da Silva F: Cathelicidin LL-37 bloodstream surveillance is
down regulated during septic shock. Microbes Infect. 15:342–346.
2013.PubMed/NCBI View Article : Google Scholar : (In English,
Spanish).
|
31
|
Nagaoka I, Tamura H and Reich J:
Therapeutic potential of cathelicidin peptide LL-37, an
antimicrobial agent, in a murine sepsis model. Int J Mol Sci.
21(5973)2020.PubMed/NCBI View Article : Google Scholar
|
32
|
Cai S, Qiao X, Feng L, Shi N, Wang H, Yang
H, Guo Z, Wang M, Chen Y, Wang Y and Yu H: Python cathelicidin
CATHPb1 protects against multidrug-resistant staphylococcal
infections by antimicrobial-immunomodulatory duality. J Med Chem.
61:2075–2086. 2018.PubMed/NCBI View Article : Google Scholar
|
33
|
Gupta V, Kumar V and Singh SK: Low vitamin
D levels are associated with an adverse clinical outcome in febrile
neutropenia. J Pediatr Hematol Oncol. 38:202–204. 2016.PubMed/NCBI View Article : Google Scholar
|
34
|
Leow L, Simpson T, Cursons R, Karalus N
and Hancox RJ: Vitamin D, innate immunity and outcomes in community
acquired pneumonia. Respirology. 16:611–616. 2011.PubMed/NCBI View Article : Google Scholar
|
35
|
Greulich T, Regner W, Branscheidt M, Herr
C, Koczulla AR, Vogelmeier CF and Bals R: Altered blood levels of
vitamin D, cathelicidin and parathyroid hormone in patients with
sepsis-a pilot study. Anaesth Intensive Care. 45:36–45.
2017.PubMed/NCBI View Article : Google Scholar
|
36
|
Jungrungrueng T, Anugulruengkitt S,
Lauhasurayotin S, Chiengthong K, Poparn H, Sosothikul D and
Techavichit P: The pattern of microorganisms and drug
susceptibility in pediatric oncologic patients with febrile
neutropenia. J Pathog. 2021(6692827)2021.PubMed/NCBI View Article : Google Scholar
|
37
|
Suttitossatam I, Satayasai W,
Sinlapamongkolkul P, Pusongchai T, Sritipsukho P and Surapolchai P:
Predictors of severe adverse outcomes in febrile neutropenia of
pediatric oncology patients at a single institute in Thailand.
Pediatr Hematol Oncol. 37:561–572. 2020.PubMed/NCBI View Article : Google Scholar
|
38
|
Rabagliati BR, Fuentes LG, Orellana UE,
Oporto CJ, Domínguez MI, Benítez GR, Aedo CI, Ramos GG, Garrido SM
and García CP: Etiology of febrile neutropenia episodes among
cancer patients from Hospital Clinico Universidad Catolica,
Santiago-chile. Rev Chilena Infectol. 26:106–113. 2009.PubMed/NCBI(In Spanish).
|
39
|
Jadhav N, Mandal J, Kayal S, Pattnaik J,
Madasamy P, Singh J and Dubashi B: Surveillance stool culture and
its association with microbiologically documented infection during
febrile neutropenia in patients with acute leukemia (AL) undergoing
induction chemotherapy. Indian J Hematol Blood Transfus.
37:543–548. 2021.PubMed/NCBI View Article : Google Scholar
|
40
|
Koenig C, Schneider C, Morgan JE, Ammann
RA, Sung L and Phillips B: Association of time to antibiotics and
clinical outcomes in patients with fever and neutropenia during
chemotherapy for cancer: A systematic review. Support Care Cancer.
28:1369–1383. 2020.PubMed/NCBI View Article : Google Scholar
|
41
|
De Castro GC, Slatnick LR, Shannon M, Zhao
Z, Jackson K, Smith CM, Whitehurst D, Elliott C, Clark CC, Scott
HF, et al: Impact of time-to-antibiotic delivery in pediatric
patients with cancer presenting with febrile neutropenia. JCO Oncol
Pract. 20:228–238. 2024.PubMed/NCBI View Article : Google Scholar
|
42
|
Simon A, Lehrnbecher T, Baltaci Y,
Dohna-Schwake C, Groll A, Laws HJ, Potratz J, Hufnagel M and
Bochennek K: Time to antibiotics (TTA)-reassessment from the German
working group for fever and neutropenia in children and adolescents
(DGPI/GPOH). Klin Padiatr. 235:331–341. 2023.PubMed/NCBI View Article : Google Scholar : (In German).
|
43
|
Handattu K, Sharma LK, Vijayasekharan K,
Bhat KV, Aroor S and Sudhanshu S: Drug Induced diabetes mellitus in
pediatric acute lymphoblastic leukemia: Approach to diagnosis and
management. J Pediatr Hematol Oncol. 44:273–279. 2022.PubMed/NCBI View Article : Google Scholar
|
44
|
Brealey D and Singer M: Hyperglycemia in
critical illness: A review. J Diabetes Sci Technol. 3:1250–1260.
2009.PubMed/NCBI View Article : Google Scholar
|
45
|
Sundén-Cullberg J, Nyström T, Lee ML,
Mullins GE, Tokics L, Andersson J, Norrby-Teglund A and Treutiger
CJ: Pronounced elevation of resistin correlates with severity of
disease in severe sepsis and septic shock. Crit Care Med.
35:1536–1542. 2007.PubMed/NCBI View Article : Google Scholar
|
46
|
Rondinelli PIP, Ribeiro K de CB and de
Camargo B: A proposed score for predicting severe infection
complications in children with chemotherapy-induced febrile
neutropenia. J Pediatr Hematol Oncol. 28:665–670. 2006.PubMed/NCBI View Article : Google Scholar
|