Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats

  • Authors:
    • Gang Sun
    • Hai Hu
    • Xuyang Tian
    • Jianwei Yue
    • Hui Yu
    • Xiaomin Yang
    • Zhanli Wang
  • View Affiliations

  • Published online on: June 25, 2013     https://doi.org/10.3892/mmr.2013.1549
  • Pages: 339-344
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

MicroRNAs (miRNAs) are involved in the regulation of numerous physiological and pathological processes. However, little information is available with regard to miRNAs in the left ventricular myocardium of the renovascular angiotensin-dependent hypertensive rat. In this study, miRNA expression profiles in the left ventricular myocardium of two-kidney one-clip (2K1C) hypertensive rats were analyzed using a microarray. The roles of the differentially expressed miRNAs, their target genes and signaling pathways were analyzed using ingenuity pathway analysis (IPA) for the first time to further elucidate the molecular mechanisms of left ventricular remodeling.
View Figures
View References

Related Articles

Journal Cover

August 2013
Volume 8 Issue 2

Print ISSN: 1791-2997
Online ISSN:1791-3004

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Sun G, Hu H, Tian X, Yue J, Yu H, Yang X and Wang Z: Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats. Mol Med Rep 8: 339-344, 2013.
APA
Sun, G., Hu, H., Tian, X., Yue, J., Yu, H., Yang, X., & Wang, Z. (2013). Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats. Molecular Medicine Reports, 8, 339-344. https://doi.org/10.3892/mmr.2013.1549
MLA
Sun, G., Hu, H., Tian, X., Yue, J., Yu, H., Yang, X., Wang, Z."Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats". Molecular Medicine Reports 8.2 (2013): 339-344.
Chicago
Sun, G., Hu, H., Tian, X., Yue, J., Yu, H., Yang, X., Wang, Z."Identification and analysis of microRNAs in the left ventricular myocardium of two-kidney one-clip hypertensive rats". Molecular Medicine Reports 8, no. 2 (2013): 339-344. https://doi.org/10.3892/mmr.2013.1549