1
|
Al-Hajj M and Clarke MF: Self-renewal and
solid tumor stem cells. Oncogene. 23:7274–7282. 2004. View Article : Google Scholar : PubMed/NCBI
|
2
|
Sampieri K and Fodde R: Cancer stem cells
and metastasis. Semin Cancer Biol. 22:187–193. 2012. View Article : Google Scholar : PubMed/NCBI
|
3
|
Ishii H, Iwatsuki M, Ieta K, Ohta D,
Haraguchi N, Mimori K and Mori M: Cancer stem cells and
chemoradiation resistance. Cancer Sci. 99:1871–1877. 2008.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Li X, Lewis MT, Huang J, Gutierrez C,
Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC,
et al: Intrinsic resistance of tumorigenic breast cancer cells to
chemotherapy. J Natl Cancer Inst. 100:672–679. 2008. View Article : Google Scholar : PubMed/NCBI
|
5
|
McDermott SP and Wicha MS: Targeting
breast cancer stem cells. Mol Oncol. 4:404–419. 2010. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ingham PW and McMahon AP: Hedgehog
signaling in animal development: Paradigms and principles. Genes
Dev. 15:3059–3087. 2001. View Article : Google Scholar : PubMed/NCBI
|
7
|
Taipale J and Beachy PA: The Hedgehog and
Wnt signalling pathways in cancer. Nature. 411:349–354. 2001.
View Article : Google Scholar : PubMed/NCBI
|
8
|
Jiang J and Hui CC: Hedgehog signaling in
development and cancer. Dev Cell. 15:801–812. 2008. View Article : Google Scholar : PubMed/NCBI
|
9
|
Briscoe J and Thérond PP: The mechanisms
of Hedgehog signalling and its roles in development and disease.
Nat Rev Mol Cell Biol. 14:416–429. 2013. View Article : Google Scholar : PubMed/NCBI
|
10
|
Liu S, Dontu G, Mantle ID, Patel S, Ahn
NS, Jackson KW, Suri P and Wicha MS: Hedgehog signaling and Bmi-1
regulate self-renewal of normal and malignant human mammary stem
cells. Cancer Res. 66:6063–6071. 2006. View Article : Google Scholar : PubMed/NCBI
|
11
|
Bar EE, Chaudhry A, Lin A, Fan X, Schreck
K, Matsui W, Piccirillo S, Vescovi AL, DiMeco F, Olivi A and
Eberhart CG: Cyclopamine-mediated hedgehog pathway inhibition
depletes stem-like cancer cells in glioblastoma. Stem Cells.
25:2524–2533. 2007. View Article : Google Scholar : PubMed/NCBI
|
12
|
Clement V, Sanchez P, de Tribolet N,
Radovanovic I and Ruiz i Altaba A: HEDGEHOG-GLI1 signaling
regulates human glioma growth, cancer stem cell self-renewal, and
tumorigenicity. Curr Biol. 17:165–172. 2007. View Article : Google Scholar : PubMed/NCBI
|
13
|
Zhao C, Chen A, Jamieson CH, Fereshteh M,
Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, et al:
Hedgehog signalling is essential for maintenance of cancer stem
cells in myeloid leukaemia. Nature. 458:776–779. 2009. View Article : Google Scholar : PubMed/NCBI
|
14
|
Tanaka H, Nakamura M, Kameda C, Kubo M,
Sato N, Kuroki S, Tanaka M and Katano M: The Hedgehog signaling
pathway plays an essential role in maintaining the
CD44+CD24−/low subpopulation and the side
population of breast cancer cells. Anticancer Res. 29:2147–2157.
2009.PubMed/NCBI
|
15
|
Jaggupilli A and Elkord E: Significance of
CD44 and CD24 as cancer stem cell markers: An enduring ambiguity.
Clin Dev Immunol. 2012:7080362012. View Article : Google Scholar : PubMed/NCBI
|
16
|
Al-Hajj M, Wicha MS, Benito-Hernandez A,
Morrison SJ and Clarke MF: Prospective identification of
tumorigenic breast cancer cells. Proc Natl Acad Sci USA.
100:3983–3988. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Abraham BK, Fritz P, McClellan M,
Hauptvogel P, Athelogou M and Brauch H: Prevalence of
CD44+/CD24−/low cells in breast cancer may
not be associated with clinical outcome but may favor distant
metastasis. Clin Cancer Res. 11:1154–1159. 2005.PubMed/NCBI
|
18
|
Sheridan C, Kishimoto H, Fuchs RK,
Mehrotra S, Bhat-Nakshatri P, Turner CH, Goulet R Jr, Badve S and
Nakshatri H: CD44+/CD24− breast cancer cells
exhibit enhanced invasive properties: An early step necessary for
metastasis. Breast Cancer Res. 8:R592006. View Article : Google Scholar : PubMed/NCBI
|
19
|
Lin Y, Zhong Y, Guan H, Zhang X and Sun Q:
CD44+/CD24− phenotype contributes to
malignant relapse following surgical resection and chemotherapy in
patients with invasive ductal carcinoma. J Exp Clin Cancer Res.
31:592012. View Article : Google Scholar : PubMed/NCBI
|
20
|
Lee HE, Kim JH, Kim YJ, Choi SY, Kim SW,
Kang E, Chung IY, Kim IA, Kim EJ, Choi Y, et al: An increase in
cancer stem cell population after primary systemic therapy is a
poor prognostic factor in breast cancer. Br J Cancer.
104:1730–1738. 2011. View Article : Google Scholar : PubMed/NCBI
|
21
|
Tavassoli FA and Devilee P: World Health
Organization Classification of Tumours Pathology and Genetics
Tumours of the Breast and Female Genital Organs. IARC Press; Lyon:
2003
|
22
|
Bai X, Song Z, Fu Y, Yu Z, Zhao L, Zhao H,
Yao W, Huang D, Mi X, Wang E, et al: Clinicopathological
significance and prognostic value of DNA methyltransferase 1, 3a,
and 3b expressions in sporadic epithelial ovarian cancer. PLoS One.
7:e400242012. View Article : Google Scholar : PubMed/NCBI
|
23
|
Kim TJ, Lee JY, Hwang TK, Kang CS and Choi
YJ: Hedgehog signaling protein expression and its association with
prognostic parameters in prostate cancer: A retrospective study
from the view point of new 2010 anatomic stage/prognostic groups. J
Surg Oncol. 104:472–479. 2011. View Article : Google Scholar : PubMed/NCBI
|
24
|
He HC, Chen JH, Chen XB, Qin GQ, Cai C,
Liang YX, Han ZD, Dai QS, Chen YR, Zeng GH, et al: Expression of
hedgehog pathway components is associated with bladder cancer
progression and clinical outcome. Pathol Oncol Res. 18:349–355.
2012. View Article : Google Scholar : PubMed/NCBI
|
25
|
Kim BW, Cho H, Chung JY, Conway C, Ylaya
K, Kim JH and Hewitt SM: Prognostic assessment of hypoxia and
metabolic markers in cervical cancer using automated digital image
analysis of immunohistochemistry. J Transl Med. 11:1852013.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Liu H, Patel MR, Prescher JA, Patsialou A,
Qian D, Lin J, Wen S, Chang YF, Bachmann MH, Shimono Y, et al:
Cancer stem cells from human breast tumors are involved in
spontaneous metastases in orthotopic mouse models. Proc Natl Acad
Sci USA. 107:18115–18120. 2010. View Article : Google Scholar : PubMed/NCBI
|
27
|
Song Z, Yue W, Wei B, Wang N, Li T, Guan
L, Shi S, Zeng Q, Pei X and Chen L: Sonic hedgehog pathway is
essential for maintenance of cancer stem-like cells in human
gastric cancer. PLoS One. 6:e176872011. View Article : Google Scholar : PubMed/NCBI
|
28
|
Kubo M, Nakamura M, Tasaki A, Yamanaka N,
Nakashima H, Nomura M, Kuroki S and Katano M: Hedgehog signaling
pathway is a new therapeutic target for patients with breast
cancer. Cancer Res. 64:6071–6074. 2004. View Article : Google Scholar : PubMed/NCBI
|
29
|
Im S, Choi HJ, Yoo C, Jung JH, Jeon YW,
Suh YJ and Kang CS: Hedgehog related protein expression in breast
cancer: Gli-2 is associated with poor overall survival. Korean J
Pathol. 47:116–123. 2013. View Article : Google Scholar : PubMed/NCBI
|
30
|
Tao Y, Mao J, Zhang Q and Li L:
Overexpression of Hedgehog signaling molecules and its involvement
in triple-negative breast cancer. Oncol Lett. 2:995–1001.
2011.PubMed/NCBI
|
31
|
Xuan Y and Lin Z: Expression of Indian
Hedgehog signaling molecules in breast cancer. J Cancer Res Clin
Oncol. 135:235–240. 2009. View Article : Google Scholar : PubMed/NCBI
|
32
|
Liu R, Wang X, Chen GY, Dalerba P, Gurney
A, Hoey T, Sherlock G, Lewicki J, Shedden K and Clarke MF: The
prognostic role of a gene signature from tumorigenic breast-cancer
cells. N Engl J Med. 356:217–226. 2007. View Article : Google Scholar : PubMed/NCBI
|
33
|
Charafe-Jauffret E, Ginestier C and
Birnbaum D: Breast cancer stem cells: Tools and models to rely on.
BMC Cancer. 9:2022009. View Article : Google Scholar : PubMed/NCBI
|
34
|
Ramaswamy B, Lu Y, Teng KY, Nuovo G, Li X,
Shapiro CL and Majumder S: Hedgehog signaling is a novel
therapeutic target in tamoxifen-resistant breast cancer aberrantly
activated by PI3K/AKT pathway. Cancer Res. 72:5048–5059. 2012.
View Article : Google Scholar : PubMed/NCBI
|