Protective role of taurine against oxidative stress (Review)
- Authors:
- Stella Baliou
- Maria Adamaki
- Petros Ioannou
- Aglaia Pappa
- Mihalis I. Panayiotidis
- Demetrios A. Spandidos
- Ioannis Christodoulou
- Anthony M. Kyriakopoulos
- Vassilis Zoumpourlis
-
Affiliations: National Hellenic Research Foundation, 11635 Athens, Greece, Department of Internal Medicine and Infectious Diseases, University Hospital of Heraklion, 71110 Heraklion, Greece, Department of Molecular Biology and Genetics, Faculty of Health Sciences, Democritus University of Thrace, 68100 Alexandroupolis, Greece, Department of Cancer Genetics, Therapeutics and Ultrastructural Pathology, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus, Nasco AD Biotechnology Laboratory, 18536 Pireus, Greece - Published online on: June 24, 2021 https://doi.org/10.3892/mmr.2021.12242
- Article Number: 605
This article is mentioned in:
Abstract
Tiedemann F and Gmelin L: Einige neue bestandtheile der galle des ochsen. Ann Phys. 85:326–337. 1827. View Article : Google Scholar | |
Kim SJ, Lee HW and Gupta RC: Taurine, Bone growth and bone development. Curr Nutr Food Sci. 4:135–144. 2008. View Article : Google Scholar | |
Hayes KC, Carey RE and Schmidt SY: Retinal degeneration associated with taurine deficiency in the cat. Science. 188:949–951. 1975. View Article : Google Scholar : PubMed/NCBI | |
Aerts L and Van Assche FA: Taurine and taurine-deficiency in the perinatal period. J Perinat Med. 30:281–286. 2002. View Article : Google Scholar : PubMed/NCBI | |
Chesney RW: Taurine: Its biological role and clinical implications. Adv Pediatr. 32:1–42. 1985.PubMed/NCBI | |
Lee JY, Jung DW, Park HA, Kim SJ, Chung JH, Moon CK and Kim YC: Effect of taurine on biliary excretion and metabolism of acetaminophen in male hamsters. Biol Pharm Bull. 27:1792–1796. 2004. View Article : Google Scholar : PubMed/NCBI | |
Liu QR, López-Corcuera B, Nelson H, Mandiyan S and Nelson N: Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain. Proc Natl Acad Sci USA. 89:12145–12149. 1992. View Article : Google Scholar : PubMed/NCBI | |
Chesney RW, Lippincott S, Gusowski N, Padilla M and Zelikovic I: Studies on renal adaptation to altered dietary amino acid intake: Tissue taurine responses in nursing and adult rats. J Nutr. 116:1965–1976. 1986. View Article : Google Scholar : PubMed/NCBI | |
Räihä NC, Heinonen K, Rassin DK and Gaull GE: Milk protein quantity and quality in low-birthweight infants: I. Metabolic responses and effects on growth. Pediatrics. 57:659–684. 1976. | |
Park E, Park SY, Wang C, Xu J, LaFauci G and Schuller-Levis G: Cloning of murine cysteine sulfinic acid decarboxylase and its mRNA expression in murine tissues. Biochim Biophys Acta. 1574:403–406. 2002. View Article : Google Scholar : PubMed/NCBI | |
Bella DL, Kwon YH, Hirschberger LL and Stipanuk MH: Post-transcriptional regulation of cysteine dioxygenase in rat liver. Adv Exp Med Biol. 483:71–85. 2000. View Article : Google Scholar : PubMed/NCBI | |
Redmond HP, Stapleton PP, Neary P and Bouchier-Hayes D: Immunonutrition: The role of taurine. Nutrition. 14:599–604. 1998. View Article : Google Scholar : PubMed/NCBI | |
Wójcik OP, Koenig KL, Zeleniuch-Jacquotte A, Costa M and Chen Y: The potential protective effects of taurine on coronary heart disease. Atherosclerosis. 208:19–25. 2010. View Article : Google Scholar | |
Hansen SH: The role of taurine in diabetes and the development of diabetic complications. Diabetes Metab Res Rev. 17:330–346. 2001. View Article : Google Scholar : PubMed/NCBI | |
Chesney RW, Han X and Patters AB: Taurine and the renal system. J Biomed Sci. 17 (Suppl 1):S42010. View Article : Google Scholar : PubMed/NCBI | |
Huxtable RJ: Physiological actions of taurine. Physiol Rev. 72:101–163. 1992. View Article : Google Scholar : PubMed/NCBI | |
Sarsour EH, Kumar MG, Chaudhuri L, Kalen AL and Goswami PC: Redox control of the cell cycle in health and disease. Antioxid Redox Signal. 11:2985–3011. 2009. View Article : Google Scholar : PubMed/NCBI | |
Chiang JY: Bile acid metabolism and signaling. Compr Physiol. 3:1191–212. 2013. View Article : Google Scholar : PubMed/NCBI | |
Goodman CA, Horvath D, Stathis C, Mori T, Croft K, Murphy RM and Hayes A: Taurine supplementation increases skeletal muscle force production and protects muscle function during and after high-frequency in vitro stimulation. J Appl Physiol (1985). 107:144–154. 2009. View Article : Google Scholar : PubMed/NCBI | |
Sturman JA and Chesney RW: Taurine in pediatric nutrition. Pediatr Clin North Am. 42:879–897. 1995. View Article : Google Scholar : PubMed/NCBI | |
Lien YH, Shapiro JI and Chan L: Effects of hypernatremia on organic brain osmoles. J Clin Invest. 85:1427–1435. 1990. View Article : Google Scholar : PubMed/NCBI | |
Lang F, Madlung J, Uhlemann AC, Risler T and Gulbins E: Cellular taurine release triggered by stimulation of the Fas(CD95) receptor in Jurkat lymphocytes. Pflugers Arch. 436:377–383. 1998. View Article : Google Scholar : PubMed/NCBI | |
Schaffer S, Takahashi K and Azuma J: Role of osmoregulation in the actions of taurine. Amino Acids. 19:527–546. 2000. View Article : Google Scholar : PubMed/NCBI | |
Yancey PH: Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses. J Exp Biol. 208:2819–2830. 2005. View Article : Google Scholar : PubMed/NCBI | |
Howard M, Fischer H, Roux J, Santos BC, Gullans SR, Yancey PH and Welch WJ: Mammalian osmolytes and S-nitrosoglutathione promote delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) protein maturation and function. J Biol Chem. 278:35159–35167. 2003. View Article : Google Scholar : PubMed/NCBI | |
Marcinkiewicz J and Kontny E: Taurine and inflammatory diseases. Amino Acids. 46:7–20. 2014. View Article : Google Scholar : PubMed/NCBI | |
Sukhotnik I, Aranovich I, Ben Shahar Y, Bitterman N, Pollak Y, Berkowitz D, Chepurov D, Coran AG and Bitterman A: Effect of taurine on intestinal recovery following intestinal ischemia-reperfusion injury in a rat. Pediatr Surg Int. 32:161–168. 2016. View Article : Google Scholar : PubMed/NCBI | |
Gharibani P, Modi J, Menzie J, Alexandrescu A, Ma Z, Tao R, Prentice H and Wu JY: Comparison between single and combined post-treatment with S-Methyl-N,N-diethylthiolcarbamate sulfoxide and taurine following transient focal cerebral ischemia in rat brain. Neuroscience. 300:460–473. 2015. View Article : Google Scholar : PubMed/NCBI | |
Yang Y, Zhang Y, Liu X, Zuo J, Wang K, Liu W and Ge J: Exogenous taurine attenuates mitochondrial oxidative stress and endoplasmic reticulum stress in rat cardiomyocytes. Acta Biochim Biophys Sin (Shanghai). 45:359–367. 2013. View Article : Google Scholar : PubMed/NCBI | |
Wang Z, Ohata Y, Watanabe Y, Yuan Y, Yoshii Y, Kondo Y, Nishizono S and Chiba T: Taurine improves lipid metabolism and increases resistance to oxidative stress. J Nutr Sci Vitaminol (Tokyo). 66:347–356. 2020. View Article : Google Scholar : PubMed/NCBI | |
Nagai K, Fukuno S, Oda A and Konishi H: Protective effects of taurine on doxorubicin-induced acute hepatotoxicity through suppression of oxidative stress and apoptotic responses. Anticancer Drugs. 27:17–23. 2016. View Article : Google Scholar : PubMed/NCBI | |
Chang CY, Shen CY, Kang CK, Sher YP, Sheu WH, Chang CC and Lee TH: Taurine protects HK-2 cells from oxidized LDL-induced cytotoxicity via the ROS-mediated mitochondrial and p53-related apoptotic pathways. Toxicol Appl Pharmacol. 279:351–363. 2014. View Article : Google Scholar : PubMed/NCBI | |
Prideaux M, Kitase Y, Kimble M, O'Connell TM and Bonewald LF: Taurine, an osteocyte metabolite, protects against oxidative stress-induced cell death and decreases inhibitors of the Wnt/β-catenin signaling pathway. Bone. 137:1153742020. View Article : Google Scholar : PubMed/NCBI | |
Lou J, Han D, Yu H, Yu G, Jin M and Kim SJ: Cytoprotective effect of taurine against hydrogen peroxide-induced oxidative stress in UMR-106 cells through the Wnt/β-catenin signaling pathway. Biomol Ther (Seoul). 26:584–590. 2018. View Article : Google Scholar : PubMed/NCBI | |
Suzuki T, Suzuki T, Wada T, Saigo K and Watanabe K: Taurine as a constituent of mitochondrial tRNAs: New insights into the functions of taurine and human mitochondrial diseases. EMBO J. 21:6581–6589. 2002. View Article : Google Scholar : PubMed/NCBI | |
Schaffer SW, Jong CJ, Ito T and Azuma J: Role of taurine in the pathologies of MELAS and MERRF. Amino Acids. 46:47–56. 2014. View Article : Google Scholar : PubMed/NCBI | |
Homma K, Toda E, Osada H, Nagai N, Era T, Tsubota K, Okano H and Ozawa Y: Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium. Redox Biol. 41:1019212021. View Article : Google Scholar : PubMed/NCBI | |
Sturman JA: Taurine in development. Physiol Rev. 73:119–147. 1993. View Article : Google Scholar : PubMed/NCBI | |
Lima L, Obregón F, Urbina M, Carreira I, Baccichet E and Peña S: Taurine concentration in human blood peripheral lymphocytes. In: Taurine 5. Advances in Experimental Medicine and Biology. Lombardini JB, Schaffer SW and Azuma J: 526. Springer; Boston, MA: pp. 297–304. 2013 | |
Iruloh CG, D'Souza SW, Speake PF, Crocker I, Fergusson W, Baker PN, Sibley CP and Glazier JD: Taurine transporter in fetal T lymphocytes and platelets: Differential expression and functional activity. Am J Physiol Cell Physiol. 292:C332–C341. 2007. View Article : Google Scholar : PubMed/NCBI | |
Oja SS and Saransaari P: Taurine 6. Advances in Experimental Medicine and Biology. 583. Springer; New York, NY: pp. p5562006 | |
Lubec B, Ya-hua Z, Pertti S, Pentti T, Kitzmüller E and Lubec G: Distribution and disappearance of the radiolabeled carbon derived from L-arginine and taurine in the mouse. Life Sci. 60:2373–2381. 1997. View Article : Google Scholar : PubMed/NCBI | |
Menzie J, Pan C, Prentice H and Wu JY: Taurine and central nervous system disorders. Amino Acids. 46:31–46. 2014. View Article : Google Scholar : PubMed/NCBI | |
Schaffer SW, Jong CJ, Ramila KC and Azuma J: Physiological roles of taurine in heart and muscle. J Biomed Sci. 17 (Suppl 1):S22010. View Article : Google Scholar : PubMed/NCBI | |
Schaffer SW, Shimada-Takaura K, Jong CJ, Ito T and Takahashi K: Impaired energy metabolism of the taurine-deficient heart. Amino Acids. 48:549–558. 2016. View Article : Google Scholar : PubMed/NCBI | |
Jong CJ, Azuma J and Schaffer S: Mechanism underlying the antioxidant activity of taurine: Prevention of mitochondrial oxidant production. Amino Acids. 42:2223–2232. 2012. View Article : Google Scholar : PubMed/NCBI | |
Jong C, Ito T, Mozaffari M, Azuma J and Schaffer S: Effect of beta-alanine treatment on mitochondrial taurine level and 5-taurinomethyluridine content. J Biomed Sci. 17 (Suppl 1):S252010. View Article : Google Scholar : PubMed/NCBI | |
Vafai SB and Mootha VK: Mitochondrial disorders as windows into an ancient organelle. Nature. 491:374–833. 2012. View Article : Google Scholar : PubMed/NCBI | |
Jansen M, Ten Klooster JP, Offerhaus GJ and Clevers H: LKB1 and AMPK family signaling: The intimate link between cell polarity and energy metabolism. Physiol. 89:777–798. 2009.PubMed/NCBI | |
Jong CJ, Azuma J and Schaffer SW: Role of mitochondrial permeability transition in taurine deficiency-induced apoptosis. Exp Clin Cardiol. 16:125–128. 2011.PubMed/NCBI | |
Ricci C, Pastukh V, Leonard J, Turrens J, Wilson G, Schaffer D and Schaffer SW: Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis. Am J Physiol Cell Physiol. 294:C413–C422. 2008. View Article : Google Scholar : PubMed/NCBI | |
Shetewy A, Shimada-Takaura K, Warner D, Jong CJ, Mehdi AB, Alexeyev M, Takahashi K and Schaffer SW: Mitochondrial defects associated with β-alanine toxicity: Relevance to hyper-beta-alaninemia. Mol Cell Biochem. 416:11–22. 2016. View Article : Google Scholar : PubMed/NCBI | |
Schuller-Levis G and Park E: Is taurine a biomarker? Adv Clin Chem. 41:1–21. 2006. View Article : Google Scholar : PubMed/NCBI | |
Cozzi R, Ricordy R, Bartolini F, Ramadori L, Perticone P and De Salvia R: Taurine and ellagic acid: Two differently-acting natural antioxidants. Environ Mol Mutagen. 26:248–254. 1995. View Article : Google Scholar : PubMed/NCBI | |
Aruoma OI, Halliwell B, Hoey BM and Butler J: The antioxidant action of taurine, hypotaurine and their metabolic precursors. Biochem J. 256:251–255. 1988. View Article : Google Scholar : PubMed/NCBI | |
Timbrell JA, Seabra V and Waterfield CJ: The in vivo and in vitro protective properties of taurine. Gen Pharmacol. 26:453–462. 1995. View Article : Google Scholar : PubMed/NCBI | |
Chen WQ, Jin H, Nguyen M, Carr J, Lee YJ, Hsu CC, Faiman MD, Schloss JV and Wu JY: Role of taurine in regulation of intracellular calcium level and neuroprotective function in cultured neurons. J Neurosci Res. 66:612–619. 2001. View Article : Google Scholar : PubMed/NCBI | |
Yamauchi-Takihara K, Azuma J, Kishimoto S, Onishi S and Sperelakis N: Taurine prevention of calcium paradox-related damage in cardiac muscle. Its regulatory action on intracellular cation contents. Biochem Pharmacol. 37:2651–2658. 1988. View Article : Google Scholar : PubMed/NCBI | |
Parvez S, Tabassum H, Banerjee BD and Raisuddin S: Taurine prevents tamoxifen-induced mitochondrial oxidative damage in mice. Basic Clin Pharmacol Toxicol. 102:382–387. 2008. View Article : Google Scholar : PubMed/NCBI | |
Sener G, Ozer Sehirli A, Ipçi Y, Cetinel S, Cikler E, Gedik N and Alican I: Taurine treatment protects against chronic nicotine-induced oxidative changes. Fundam Clin Pharmacol. 155–164. 2005. View Article : Google Scholar : PubMed/NCBI | |
Şener G, Şehirli Ö, İpçi Y, Çetinel Ş, Çikler E, Gedik N and Alican I: Protective effects of taurine against nicotine-induced oxidative damage of rat urinary bladder and kidney. Pharmacology. 74:37–44. 2005. View Article : Google Scholar | |
Jafri AJA, Agarwal R, Iezhitsa I, Agarwal P and Ismail NM: Taurine protects against NMDA-induced retinal damage by reducing retinal oxidative stress. Amino Acids. 51:641–646. 2019. View Article : Google Scholar : PubMed/NCBI | |
Gordon RE and Heller RF and Heller RF: Taurine protection of lungs in hamster models of oxidant injury: A morphologic time study of paraquat and bleomycin treatment. Taurine. Advances in Experimental Medicine and Biology. Lombardini JB, Schaffer SW and Azuma J: 315. Springer; Boston, MA: pp. 319–328. 1992, View Article : Google Scholar : PubMed/NCBI | |
Kim C and Cha YN: Taurine chloramine produced from taurine under inflammation provides anti-inflammatory and cytoprotective effects. Amino Acids. 46:89–100. 2014. View Article : Google Scholar : PubMed/NCBI | |
Hsieh TJ, Zhang SL, Filep JG, Tang SS, Ingelfinger JR and Chan JS: High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. Endocrinology. 143:2975–2985. 2002. View Article : Google Scholar : PubMed/NCBI | |
Kettle AJ, van Dalen CJ and Winterbourn CC: Peroxynitrite and myeloperoxidase leave the same footprint in protein nitration. Redox Rep. 3:257–258. 1997. View Article : Google Scholar : PubMed/NCBI | |
Schaffer S, Solodushko V, Pastukh V, Ricci C and Azuma J: Possible cause of taurine-deficient cardiomyopathy: Potentiation of angiotensin II action. J Cardiovasc Pharmacol. 41:751–759. 2003. View Article : Google Scholar : PubMed/NCBI | |
Vohra BP and Hui X: Taurine protects against carbon tetrachloride toxicity in the cultured neurons and in vivo. Arch Physiol Biochem. 109:90–94. 2001. View Article : Google Scholar : PubMed/NCBI | |
Nonaka H, Tsujino T, Watari Y, Emoto N and Yokoyama M: Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine: Amelioration of homocysteine-induced endoplasmic reticulum stress by taurine. Circulation. 104:1165–1170. 2001. View Article : Google Scholar : PubMed/NCBI | |
Anand P, Rajakumar D, Jeraud M, Felix AJ and Balasubram T: Effects of taurine on glutathione peroxidase, glutathione reductase and reduced glutathione levels in rats. Pak J Biol Sci. 14:219–225. 2011. View Article : Google Scholar : PubMed/NCBI | |
Oudit GY, Trivieri MG, Khaper N, Husain T, Wilson GJ, Liu P, Sole MJ and Backx PH: Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model. Circulation. 109:1877–1885. 2004. View Article : Google Scholar : PubMed/NCBI | |
Das J and Sil PC: Taurine ameliorates alloxan-induced diabetic renal injury, oxidative stress-related signaling pathways and apoptosis in rats. Amino Acids. 43:1509–1523. 2012. View Article : Google Scholar : PubMed/NCBI | |
Sayed RH, Salem HA and El-Sayeh BM: Potential protective effect of taurine against dibromoacetonitrile-induced neurotoxicity in rats. Environ Toxicol Pharmacol. 34:849–857. 2012. View Article : Google Scholar : PubMed/NCBI | |
Das J, Ghosh J, Manna P and Sil PC: Taurine protects rat testes against doxorubicin-induced oxidative stress as well as p53, Fas and caspase 12-mediated apoptosis. Amino Acids. 42:1839–1855. 2012. View Article : Google Scholar : PubMed/NCBI | |
Bhavsar TM, Cantor JO, Patel SN and Lau-Cam CA: Attenuating effect of taurine on lipopolysaccharide-induced acute lung injury in hamsters. Pharmacol Res. 60:418–428. 2009. View Article : Google Scholar : PubMed/NCBI | |
Ito T, Schaffer SW and Azuma J: The potential usefulness of taurine on diabetes mellitus and its complications. Amino Acids. 42:1529–1539. 2012. View Article : Google Scholar : PubMed/NCBI | |
Rikimaru M, Ohsawa Y, Wolf AM, Nishimaki K, Ichimiya H, Kamimura N, Nishimatsu S, Ohta S and Sunada Y: Taurine ameliorates impaired the mitochondrial function and prevents stroke-like episodes in patients with MELAS. Intern Med. 51:3351–3357. 2012. View Article : Google Scholar : PubMed/NCBI | |
Hagar HH, El Etter E and Arafa M: Taurine attenuates hypertension and renal dysfunction induced by cyclosporine a in rats. Clin Exp Pharmacol Physiol. 33:189–196. 2006. View Article : Google Scholar : PubMed/NCBI | |
Shao X, Hu Z, Hu C, Bu Q, Yan G, Deng P, Lv L, Wu D, Deng Y, Zhao J, et al: Taurine protects methamphetamine-induced developmental angiogenesis defect through antioxidant mechanism. Toxicol Appl Pharmacol. 260:260–270. 2012. View Article : Google Scholar : PubMed/NCBI | |
Brosnan JT and Brosnan ME: The sulfur-containing amino acids: An overview. J Nutr. 136 (Suppl 6):1636S–1640S. 2006. View Article : Google Scholar : PubMed/NCBI | |
Wenting L, Ping L, Haitao J, Meng Q and Xiaofei R: Therapeutic effect of taurine against aluminum-induced impairment on learning, memory and brain neurotransmitters in rats. Neurol. 35:1579–1584. 2014.PubMed/NCBI | |
Albrecht J and Schousboe A: Taurine interaction with neurotransmitter receptors in the CNS: An update. Neurochem Res. 30:1615–1621. 2005. View Article : Google Scholar : PubMed/NCBI | |
Wu H, Jin Y, Wei J, Jin H, Sha D and Wu JY: Mode of action of taurine as a neuroprotector. Brain Res. 1038:123–131. 2005. View Article : Google Scholar : PubMed/NCBI | |
Chen C, Xia S, He J, Lu G, Xie Z and Han H: Roles of taurine in cognitive function of physiology, pathologies and toxication. Life Sci. 231:1165842019. View Article : Google Scholar : PubMed/NCBI | |
Ochoa-de la Paz L, Zenteno E, Gulias-Cañizo R and Quiroz-Mercado H: Taurine and GABA neurotransmitter receptors, a relationship with therapeutic potential? Expert Rev Neurother. 19:289–291. 2019. View Article : Google Scholar : PubMed/NCBI | |
Zhou J, Li Y, Yan G, Bu Q, Lv L, Yang Y, Zhao J, Shao X, Deng Y, Zhu R, et al: Protective role of taurine against morphine-induced neurotoxicity in C6 cells via inhibition of oxidative stress. Neurotox Res. 20:334–342. 2011. View Article : Google Scholar : PubMed/NCBI | |
Bulley S and Shen W: Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons. J Biomed Sci. 17 (Suppl 1):S52010. View Article : Google Scholar : PubMed/NCBI | |
Makarova LM, Pogorelyĭ VE, Voronkov AV and Novikova NA: Modern notions about the role of taurine in the central nervous system. Eksp Klin Farmakol. 77:38–44. 2014.(In Russian). PubMed/NCBI | |
Wu JY and Prentice H: Role of taurine in the central nervous system. J Biomed Sci. 17 (Suppl 1):S12010. View Article : Google Scholar : PubMed/NCBI | |
Zhang C, Liu F, Liu X and Chen D: Protective effect of N-acetylcysteine against BDE-209-induced neurotoxicity in primary cultured neonatal rat hippocampal neurons in vitro. Int J Dev Neurosci. 28:521–528. 2010. View Article : Google Scholar : PubMed/NCBI | |
Abramov AY and Duchen MR: Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity. Biochim Biophys Acta. 1777:953–964. 2008. View Article : Google Scholar : PubMed/NCBI | |
Prentice H, Modi JP and Wu JY: Mechanisms of neuronal protection against excitotoxicity, endoplasmic reticulum stress, and mitochondrial dysfunction in stroke and neurodegenerative diseases. Oxid Med Cell Longev. 2015:9645182015. View Article : Google Scholar : PubMed/NCBI | |
McCullough KD, Martindale JL, Klotz LO, Aw TY and Holbrook NJ: Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol. 21:1249–1259. 2001. View Article : Google Scholar : PubMed/NCBI | |
Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP and Ron D: Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science. 287:664–666. 2000. View Article : Google Scholar : PubMed/NCBI | |
Zhang R, Jiang M, Zhang J, Qiu Y, Li D, Li S, Liu J, Liu C, Fang Z and Cao F: Regulation of the cerebrovascular smooth muscle cell phenotype by mitochondrial oxidative injury and endoplasmic reticulum stress in simulated microgravity rats via the PERK-eIF2α-ATF4-CHOP pathway. Biochim Biophys Acta Mol Basis Dis. 1866:1657992020. View Article : Google Scholar : PubMed/NCBI | |
Aslan Karakelle N, Dinçer S and Yar Sağlam AS: The effect of intracerebroventricular amyloid beta 1–42 application on cognitive functions in aged rats supplemented with taurine and the change of peroxisomal proteins in this process. Brain Res Bull. 172:89–97. 2021. View Article : Google Scholar : PubMed/NCBI | |
Lee DS and Cheong SH: Taurine have neuroprotective activity against oxidative damage-induced HT22 Cell death through heme oxygenase-1 pathway. Taurine 10. Advances in Experimental Medicine and Biology. Lee DH, Schaffer SW, Park E and Kim HW: 975. Springer; Dordrecht: pp. 159–171. 2017, View Article : Google Scholar : PubMed/NCBI | |
Zhang X, Wang X, Zhang J, Pan X, Jiang J and Li Y: Effects of taurine on alterations of neurobehavior and neurodevelopment key proteins expression in infant rats by exposure to hexabromocyclododecane. Taurine 10. Advances in Experimental Medicine and Biology. Lee DH, Schaffer SW, Park E and Kim HW: 975. Springer; Dordrecht: pp. 119–30. 2017, View Article : Google Scholar : PubMed/NCBI | |
Chen R, Liu S, Piao F, Wang Z, Qi Y, Li S, Zhang D and Shen J: 2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway. Ind Health. 53:222–235. 2015. View Article : Google Scholar : PubMed/NCBI | |
Liu S, Piao F, Sun X, Bai L, Peng Y, Zhong Y, Ma N and Sun W: Arsenic-induced inhibition of hippocampal neurogenesis and its reversibility. Neurotoxicology. 33:1033–1039. 2012. View Article : Google Scholar : PubMed/NCBI | |
Yorifuji T, Kato T, Ohta H, Bellinger DC, Matsuoka K and Grandjean P: Neurological and neuropsychological functions in adults with a history of developmental arsenic poisoning from contaminated milk powder. Neurotoxicol Teratol. 53:75–80. 2016. View Article : Google Scholar : PubMed/NCBI | |
Li K, Wang D, Zhou X, Shao J, Li Y, Liu X, Zhang C, Zuo E, Shi X, Piao F and Li S: Taurine protects against arsenic-induced apoptosis Via PI3K/Akt pathway in primary cortical neurons. In: Taurine 11. Advances in Experimental Medicine and Biology. Hu J, Piao F, Schaffer SW, El Idrissi A and Wu JY: 1155. Springer; Singapore: pp. 747–754. 2019, PubMed/NCBI | |
Piao F, Zhang Y, Yang L, Zhang C, Shao J, Liu X, Li Y and Li S: Taurine attenuates As2O3-induced autophagy in cerebrum of mouse through Nrf2 pathway. Adv Exp Med Biol. 975:863–870. 2017. View Article : Google Scholar : PubMed/NCBI | |
Cholanians AB, Phan AV, Ditzel EJ, Camenisch TD, Lau SS and Monks TJ: From the cover: Arsenic induces accumulation of α-synuclein: Implications for synucleinopathies and neurodegeneration. Toxicol Sci. 153:271–281. 2016. View Article : Google Scholar : PubMed/NCBI | |
Escudero-Lourdes C: Toxicity mechanisms of arsenic that are shared with neurodegenerative diseases and cognitive impairment: Role of oxidative stress and inflammatory responses. Neurotoxicology. 53:223–235. 2016. View Article : Google Scholar : PubMed/NCBI | |
Lee J, Giordano S and Zhang J: Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling. Biochem J. 441:523–540. 2012. View Article : Google Scholar : PubMed/NCBI | |
Zhu XX, Yao XF, Jiang LP, Geng CY, Zhong LF, Yang G, Zheng BL and Sun XC: Sodium arsenite induces ROS-dependent autophagic cell death in pancreatic β-cells. Food Chem Toxicol. 70:144–150. 2014. View Article : Google Scholar : PubMed/NCBI | |
Li Y, Hu Z, Chen B, Bu Q, Lu W, Deng Y, Zhu R, Shao X, Hou J, Zhao J, et al: Taurine attenuates methamphetamine-induced autophagy and apoptosis in PC12 cells through mTOR signaling pathway. Toxicol Lett. 215:1–7. 2012. View Article : Google Scholar : PubMed/NCBI | |
Menzie J, Prentice H and Wu JY: Neuroprotective mechanisms of taurine against ischemic stroke. Brain Sci. 3:877–907. 2013. View Article : Google Scholar : PubMed/NCBI | |
Schaffer SW, Jong CJ, Ito T and Azuma J: Effect of taurine on ischemia-reperfusion injury. Amino Acids. 46:21–30. 2014. View Article : Google Scholar : PubMed/NCBI | |
Yamori Y, Liu L, Mori M, Sagara M, Murakami S, Nara Y and Mizushima S: Taurine as the nutritional factor for the longevity of the japanese revealed by a world-wide epidemiological survey. In: Taurine 7. Advances in Experimental Medicine and Biology. Azuma J, Schaffer SW and Ito T: 643. Springer; New York, NY: pp. 13–25. 2009, PubMed/NCBI | |
Lotocki G, de Rivero Vaccari JP, Perez ER, Sanchez-Molano J, Furones-Alonso O, Bramlett HM and Dietrich WD: Alterations in blood-brain barrier permeability to large and small molecules and leukocyte accumulation after traumatic brain injury: Effects of post-traumatic hypothermia. J Neurotrauma. 26:1123–1134. 2009. View Article : Google Scholar : PubMed/NCBI | |
Sun Q, Hu H, Wang W, Jin H, Feng G and Jia N: Taurine attenuates amyloid β 1–42-induced mitochondrial dysfunction by activating of SIRT1 in SK-N-SH cells. Biochem Biophys Res Commun. 447:485–489. 2014. View Article : Google Scholar : PubMed/NCBI | |
Niu X, Zheng S, Liu H and Li S: Protective effects of taurine against inflammation, apoptosis, and oxidative stress in brain injury. Mol Med Rep. 18:4516–4522. 2018.PubMed/NCBI | |
Saransaari P and Oja SS: Enhanced taurine release in cultured cerebellar granule cells in cell-damaging conditions. Amino Acids. 17:323–334. 1999. View Article : Google Scholar : PubMed/NCBI | |
Ricci L, Valoti M, Sgaragli G and Frosini M: Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage. Eur J Pharmacol. 621:26–32. 2009. View Article : Google Scholar : PubMed/NCBI | |
Abramov AY, Scorziello A and Duchen MR: Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J Neurosci. 27:1129–1138. 2007. View Article : Google Scholar : PubMed/NCBI | |
Han Z, Gao LY, Lin YH, Chang L, Wu HY, Luo CX and Zhu DY: Neuroprotection of taurine against reactive oxygen species is associated with inhibiting NADPH oxidases. Eur J Pharmacol. 777:129–135. 2016. View Article : Google Scholar : PubMed/NCBI | |
Pion PD, Kittleson MD, Rogers QR and Morris JG: Myocardial failure in cats associated with low plasma taurine: A reversible cardiomyopathy. Science. 237:764–768. 1987. View Article : Google Scholar : PubMed/NCBI | |
Moise NS, Pacioretty LM, Kallfelz FA, Stipanuk MH, King JM and Gilmour RF Jr: Dietary taurine deficiency and dilated cardiomyopathy in the fox. Am Heart J. 121:541–547. 1991. View Article : Google Scholar : PubMed/NCBI | |
Lake N: Loss of cardiac myofibrils: Mechanism of contractile deficits induced by taurine deficiency. Am J Physiol. 264:H1323–H1326. 1993.PubMed/NCBI | |
Ito T, Kimura Y, Uozumi Y, Takai M, Muraoka S, Matsuda T, Ueki K, Yoshiyama M, Ikawa M, Okabe M, et al: Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy. J Mol Cell Cardiol. 44:927–937. 2008. View Article : Google Scholar : PubMed/NCBI | |
Ito T, Oishi S, Takai M, Kimura Y, Uozumi Y, Fujio Y, Schaffer SW and Azuma J: Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice. J Biomed Sci. 17 (Suppl 1):S202010. View Article : Google Scholar : PubMed/NCBI | |
Huxtable R and Bressler R: Taurine concentrations in congestive heart failure. Science. 184:1187–1188. 1974. View Article : Google Scholar : PubMed/NCBI | |
Jacobsen JG and Smith LH: Biochemistry and physiology of taurine and taurine derivatives. Physiol Rev. 48:424–511. 1968. View Article : Google Scholar : PubMed/NCBI | |
Huxtable RJ and Sebring LA: Cardiovascular actions of taurine. Prog Clin Biol Res. 125:5–37. 1983.PubMed/NCBI | |
Suwanich A, Wyss JM and Roysommuti S: Taurine supplementation in spontaneously hypertensive rats: Advantages and limitations for human applications. World J Cardiol. 5:404–409. 2013. View Article : Google Scholar : PubMed/NCBI | |
Bousquet P, Feldman J, Bloch R and Schwartz J: Central cardiovascular effects of taurine: Comparison with homotaurine and muscimol. J Pharmacol Exp Ther. 219:213–218. 1981.PubMed/NCBI | |
Satoh H: Cardioprotective actions of taurine against intracellular and extracellular calcium-induced effects. Taurine in Health and Disease. Advances in Experimental Medicine and Biology. Huxtable RJ and Michalk D: 359. Springer; Boston, MA: pp. 181–196. 1994, View Article : Google Scholar : PubMed/NCBI | |
Qi B, Yamagami T, Naruse Y, Sokejima S and Kagamimori S: Effects of taurine on depletion of erythrocyte membrane Na-K ATPase activity due to ozone exposure or cholesterol enrichment. J Nutr Sci Vitaminol (Tokyo). 41:627–634. 1995. View Article : Google Scholar : PubMed/NCBI | |
Petty MA, Kintz J and DiFrancesco GF: The effects of taurine on atherosclerosis development in cholesterol-fed rabbits. Eur J Pharmacol. 180:119–127. 1990. View Article : Google Scholar : PubMed/NCBI | |
Murakami S, Sakurai T, Tomoike H, Sakono M, Nasu T and Fukuda N: Prevention of hypercholesterolemia and atherosclerosis in the hyperlipidemia- and atherosclerosis-prone Japanese (LAP) quail by taurine supplementation. Amino Acids. 38:271–278. 2010. View Article : Google Scholar : PubMed/NCBI | |
Murakami S, Nara Y and Yamori Y: Taurine accelerates the regression of hypercholesterolemia in stroke-prone spontaneously hypertensive rats. Life Sci. 58:1643–1651. 1996. View Article : Google Scholar : PubMed/NCBI | |
Yokogoshi H, Mochizuki H, Nanami K, Hida Y, Miyachi F and Oda H: Dietary taurine enhances cholesterol degradation and reduces serum and liver cholesterol concentrations in rats fed a high-cholesterol diet. J Nutr. 129:1705–1712. 1999. View Article : Google Scholar : PubMed/NCBI | |
Lam NV, Chen W, Suruga K, Nishimura N, Goda T and Yokogoshi H: Enhancing effect of taurine on CYP7A1 mRNA expression in Hep G2 cells. Amino Acids. 30:43–48. 2006. View Article : Google Scholar : PubMed/NCBI | |
Bellentani S, Pecorari M, Cordoma P, Marchegiano P, Manenti F, Bosisio E, De Fabiani E and Galli G: Taurine increases bile acid pool size and reduces bile saturation index in the hamster. J Lipid Res. 28:1021–1027. 1987. View Article : Google Scholar : PubMed/NCBI | |
Yanagita T, Han SY, Hu Y, Nagao K, Kitajima H and Murakami S: Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells. Lipids Health Dis. 7:382008. View Article : Google Scholar : PubMed/NCBI | |
Ulrich-Merzenich G, Zeitler H, Vetter H and Bhonde RR: Protective effects of taurine on endothelial cells impaired by high glucose and oxidized low density lipoproteins. Eur J Nutr. 46:431–438. 2007. View Article : Google Scholar : PubMed/NCBI | |
Gokce G, Ozsarlak-Sozer G, Oran I, Oktay G, Ozkal S and Kerry Z: Taurine suppresses oxidative stress-potentiated expression of lectin-like oxidized low-density lipoprotein receptor and restenosis in balloon-injured rabbit iliac artery. Clin Exp Pharmacol Physiol. 38:811–818. 2011. View Article : Google Scholar : PubMed/NCBI | |
Matsushima Y, Sekine T, Kondo Y, Sakurai T, Kameo K, Tachibana M and Murakami S: Effects of taurine on serum cholesterol levels and development of atherosclerosis in spontaneously hyperlipidaemic mice. Clin Exp Pharmacol Physiol. 30:295–299. 2003. View Article : Google Scholar : PubMed/NCBI | |
Murakami S, Kondo-Ohta Y and Tomisawa K: Improvement in cholesterol metabolism in mice given chronic treatment of taurine and fed a high-fat diet. Life Sci. 64:83–91. 1999. View Article : Google Scholar : PubMed/NCBI | |
Chen W, Guo JX and Chang P: The effect of taurine on cholesterol metabolism. Mol Nutr Food Res. 56:681–690. 2012. View Article : Google Scholar : PubMed/NCBI | |
Mochizuki H, Takido J and Yokogoshi H: Effect of dietary taurine on endogenous hypercholesterolemia in rats fed on phenobarbital-containing diets. Biosci Biotechnol Biochem. 63:1298–1300. 1999. View Article : Google Scholar : PubMed/NCBI | |
Mochizuki H, Oda H and Yokogoshi H: Dietary taurine potentiates polychlorinated biphenyl-induced hypercholesterolemia in rats*. J Nutr Biochem. 12:109–115. 2001. View Article : Google Scholar : PubMed/NCBI | |
Zulli A, Lau E, Wijaya BP, Jin X, Sutarga K, Schwartz GD, Learmont J, Wookey PJ, Zinellu A, Carru C and Hare DL: High dietary taurine reduces apoptosis and atherosclerosis in the left main coronary artery: Association with reduced CCAAT/enhancer binding protein homologous protein and total plasma homocysteine but not lipidemia. Hypertension. 53:1017–1022. 2009. View Article : Google Scholar : PubMed/NCBI | |
Tan B, Jiang DJ, Huang H, Jia SJ, Jiang JL, Hu CP and Li YJ: Taurine protects against low-density lipoprotein-induced endothelial dysfunction by the DDAH/ADMA pathway. Vascul Pharmacol. 46:338–345. 2007. View Article : Google Scholar : PubMed/NCBI | |
Elvevoll EO, Eilertsen KE, Brox J, Dragnes BT, Falkenberg P, Olsen JO, Kirkhus B, Lamglait A and Østerud B: Seafood diets: Hypolipidemic and antiatherogenic effects of taurine and n-3 fatty acids. Atherosclerosis. 200:396–402. 2008. View Article : Google Scholar : PubMed/NCBI | |
di Wu Q, Wang JH, Fennessy F, Redmond HP and Bouchier-Hayes D: Taurine prevents high-glucose-induced human vascular endothelial cell apoptosis. Am J Physiol. 277:C1229–C1238. 1999. View Article : Google Scholar : PubMed/NCBI | |
Katakawa M, Fukuda N, Tsunemi A, Mori M, Maruyama T, Matsumoto T, Abe M and Yamori Y: Taurine and magnesium supplementation enhances the function of endothelial progenitor cells through antioxidation in healthy men and spontaneously hypertensive rats. Hypertens Res. 39:848–856. 2016. View Article : Google Scholar : PubMed/NCBI | |
Chang L, Xu J, Yu F, Zhao J, Tang X and Tang C: Taurine protected myocardial mitochondria injury induced by hyperhomocysteinemia in rats. Amino Acids. 27:37–48. 2004. View Article : Google Scholar : PubMed/NCBI | |
Ghosh J, Das J, Manna P and Sil PC: Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: Role of NF-kappa B, p38 and JNK MAPK pathway. Toxicol Appl Pharmacol. 240:73–87. 2009. View Article : Google Scholar : PubMed/NCBI | |
Mousavi K, Niknahad H, Ghalamfarsa A, Mohammadi H, Azarpira N, Ommati MM and Heidari R: Taurine mitigates cirrhosis-associated heart injury through mitochondrial-dependent and antioxidative mechanisms. Clin Exp Hepatol. 6:207–219. 2020. View Article : Google Scholar : PubMed/NCBI | |
Liu J, Ai Y, Niu X, Shang F, Li Z, Liu H, Li W, Ma W, Chen R, Wei T, et al: Taurine protects against cardiac dysfunction induced by pressure overload through SIRT1-p53 activation. Chem Biol Interact. 317:1089722020. View Article : Google Scholar : PubMed/NCBI | |
Chen G, Nan C, Tian J, Jean-Charles P, Li Y, Weissbach H and Huang XP: Protective effects of taurine against oxidative stress in the heart of MsrA knockout mice. J Cell Biochem. 113:3559–3566. 2012. View Article : Google Scholar : PubMed/NCBI | |
Rashid K, Das J and Sil PC: Taurine ameliorate alloxan induced oxidative stress and intrinsic apoptotic pathway in the hepatic tissue of diabetic rats. Food Chem Toxicol. 51:317–329. 2013. View Article : Google Scholar : PubMed/NCBI | |
Sevin G, Ozsarlak-Sozer G, Keles D, Gokce G, Reel B, Ozgur HH, Oktay G and Kerry Z: Taurine inhibits increased MMP-2 expression in a model of oxidative stress induced by glutathione depletion in rabbit heart. Eur J Pharmacol. 706:98–106. 2013. View Article : Google Scholar : PubMed/NCBI | |
Hansen SH, Andersen ML, Cornett C, Gradinaru R and Grunnet N: A role for taurine in mitochondrial function. J Biomed Sci. 17 (Suppl 1):S232010. View Article : Google Scholar : PubMed/NCBI | |
Oriyanhan W, Yamazaki K, Miwa S, Takaba K, Ikeda T and Komeda M: Taurine prevents myocardial ischemia/reperfusion-induced oxidative stress and apoptosis in prolonged hypothermic rat heart preservation. Heart Vessels. 20:278–285. 2005. View Article : Google Scholar : PubMed/NCBI | |
Sahin MA, Yucel O, Guler A, Doganci S, Jahollari A, Cingoz F, Arslan S, Gamsizkan M, Yaman H and Demirkilic U: Is there any cardioprotective role of Taurine during cold ischemic period following global myocardial ischemia? J Cardiothorac Surg. 6:312011. View Article : Google Scholar : PubMed/NCBI | |
Venturini A, Ascione R, Lin H, Polesel E, Angelini GD and Suleiman MS: The importance of myocardial amino acids during ischemia and reperfusion in dilated left ventricle of patients with degenerative mitral valve disease. Mol Cell Biochem. 330:63–70. 2009. View Article : Google Scholar : PubMed/NCBI | |
Xu YJ, Arneja AS, Tappia PS and Dhalla NS: The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 13:57–65. 2008.PubMed/NCBI | |
Jacobus WE, Tiozzo R, Lugli G, Lehninger AL and Carafoli E: Aspects of energy-linked calcium accumulation by rat heart mitochondria. J Biol Chem. 250:7863–7870. 1975. View Article : Google Scholar : PubMed/NCBI | |
Rasola A and Bernardi P: Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis. Cell Calcium. 50:222–233. 2011. View Article : Google Scholar : PubMed/NCBI | |
Zhang Y, Yang L, Yang YJ, Liu XY, Jia JG, Qian JY, Wang KQ, Zuo J and Ge J: Low-dose taurine upregulates taurine transporter expression in acute myocardial ischemia. Int J Mol Med. 31:817–824. 2013. View Article : Google Scholar : PubMed/NCBI | |
Schaffer S, Solodushko V and Azuma J: Taurine-deficient cardiomyopathy: Role of phospholipids, calcium and osmotic stress. Taurine 4. Advances in Experimental Medicine and Biology. Della Corte L, Huxtable RJ, Sgaragli G and Tipton KF: 483. Springer; Boston, MA: pp. 57–69. 2002, View Article : Google Scholar : PubMed/NCBI | |
Bagchi D, Wetscher GJ, Bagchi M, Hinder PR, Perdikis G, Stohs SJ, Hinder RA and Das DK: Interrelationship between cellular calcium homeostasis and free radical generation in myocardial reperfusion injury. Chem Biol Interact. 104:65–85. 1997. View Article : Google Scholar : PubMed/NCBI | |
Grace PA: Ischaemia-reperfusion injury. Br J Surg. 81:637–647. 1994. View Article : Google Scholar : PubMed/NCBI | |
Lemasters JJ, Nieminen AL, Qian T, Trost LC and Herman B: The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury. Mol Cell Biochem. 174:159–165. 1997. View Article : Google Scholar : PubMed/NCBI | |
Kaplan B, Aricioglu A, Erbas D, Erbas S and Turkozkan N: The effects of taurine on perfused heart muscle malondialdehyde levels. Gen Pharmacol. 24:1411–1413. 1993. View Article : Google Scholar : PubMed/NCBI | |
Ramila KC, Jong CJ, Pastukh V, Ito T, Azuma J and Schaffer SW: Role of protein phosphorylation in excitation-contraction coupling in taurine deficient hearts. Am J Physiol-Heart Circ Physiol. 308:H232–H239. 2015. View Article : Google Scholar : PubMed/NCBI | |
Modi P and Suleiman MS: Myocardial taurine, development and vulnerability to ischemia. Amino Acids. 26:65–70. 2004. View Article : Google Scholar : PubMed/NCBI | |
Tricarico D, Barbieri M and Camerino DC: Taurine blocks ATP-sensitive potassium channels of rat skeletal muscle fibres interfering with the sulphonylurea receptor. Br J Pharmacol. 130:827–834. 2000. View Article : Google Scholar : PubMed/NCBI | |
Tricarico D, Barbieri M and Conte Camerino D: Voltage-dependent antagonist/agonist actions of taurine on Ca(2+)-activated potassium channels of rat skeletal muscle fibers. J Pharmacol Exp Ther. 298:1167–1171. 2001.PubMed/NCBI | |
Shimada K, Jong CJ, Takahashi K and Schaffer SW: Role of ROS Production and Turnover in the Antioxidant Activity of Taurine. Taurine. 9:Marcinkiewicz J and Schaffer SW: 581–96. 2015. | |
Takatani T, Takahashi K, Uozumi Y, Shikata E, Yamamoto Y, Ito T, Matsuda T, Schaffer SW, Fujio Y and Azuma J: Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome. Am J Physiol Cell Physiol. 287:C949–C953. 2004. View Article : Google Scholar : PubMed/NCBI | |
Li Y, Arnold JM, Pampillo M, Babwah AV and Peng T: Taurine prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation. Free Radic Biol Med. 46:51–61. 2009. View Article : Google Scholar : PubMed/NCBI | |
Ahmadi S and Mehranjani MS: Taurine improves follicular survival and function of mice ovarian grafts through increasing CD31 and GDF9 expression and reducing oxidative stress and apoptosis. Eur J Pharmacol. 903:1741342021. View Article : Google Scholar : PubMed/NCBI | |
Ito T, Yoshikawa N, Schaffer SW and Azuma J: Tissue taurine depletion alters metabolic response to exercise and reduces running capacity in mice. J Amino Acids. 2014:9646802014. View Article : Google Scholar : PubMed/NCBI | |
Bakker AJ and Berg HM: Effect of taurine on sarcoplasmic reticulum function and force in skinned fast-twitch skeletal muscle fibres of the rat. J Physiol. 538:185–194. 2002. View Article : Google Scholar : PubMed/NCBI | |
Thirupathi A, Pinho RA, Baker JS, István B and Gu Y: Taurine reverses oxidative damages and restores the muscle function in overuse of exercised muscle. Front Physiol. 11:5824492020. View Article : Google Scholar : PubMed/NCBI | |
Dutka TL, Lamboley CR, Murphy RM and Lamb GD: Acute effects of taurine on sarcoplasmic reticulum Ca2+ accumulation and contractility in human type I and II skeletal muscle fibers. J Appl Physiol. 117:797–805. 1985. View Article : Google Scholar : PubMed/NCBI | |
De Luca A, Pierno S and Camerino DC: Taurine: The appeal of a safe amino acid for skeletal muscle disorders. J Transl Med. 13:2432015. View Article : Google Scholar : PubMed/NCBI | |
De Luca A, Pierno S and Camerino DC: Effect of taurine depletion on excitation-contraction coupling and Cl-conductance of rat skeletal muscle. Eur J Pharmacol. 296:215–222. 1996. View Article : Google Scholar : PubMed/NCBI | |
Jentsch TJ: CLC chloride channels and transporters: From genes to protein structure, pathology and physiology. Crit Rev Biochem Mol Biol. 43:3–36. 2008. View Article : Google Scholar : PubMed/NCBI | |
Hamilton EJ, Berg HM, Easton CJ and Bakker AJ: The effect of taurine depletion on the contractile properties and fatigue in fast-twitch skeletal muscle of the mouse. Amino Acids. 31:273–278. 2006. View Article : Google Scholar : PubMed/NCBI | |
Tallis J, Higgins MF, Cox VM, Duncan MJ and James RS: Does a physiological concentration of taurine increase acute muscle power output, time to fatigue, and recovery in isolated mouse soleus (slow) muscle with or without the presence of caffeine? Can J Physiol Pharmacol. 92:42–49. 2014. View Article : Google Scholar : PubMed/NCBI | |
Yatabe Y, Miyakawa S, Miyazaki T, Matsuzaki Y and Ochiai N: Effects of taurine administration in rat skeletal muscles on exercise. J Orthop Sci. 8:415–419. 2003. View Article : Google Scholar : PubMed/NCBI | |
Ohmori H, Matsumura M, Komine S, Kobayashi H, Kobayashi Y, Shiromoto J and Miyakawa S: The production of a rat model that inhibits phosphoenolpyruvate carboxykinase (PEPCK), a rate-limiting enzyme of hepatic gluconeogenesis. Taurine 11. Advances in Experimental Medicine and Biology. Hu J, Piao F, Schaffer SW, El Idrissi A and Wu JY: 1155. Springer; Singapore: pp. 113–118. 2019, View Article : Google Scholar : PubMed/NCBI | |
Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M and Zierath JR: Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes. 63:1560–1571. 2014. View Article : Google Scholar : PubMed/NCBI | |
Beloshapka AN, de Godoy MR, Carter RA, Fascetti AJ, Yu Z, McIntosh BJ, Swanson KS and Buff PR: Longitudinal changes in blood metabolites, amino acid profile, and oxidative stress markers in American foxhounds fed a nutrient-fortified diet. J Anim Sci. 96:930–940. 2018. View Article : Google Scholar : PubMed/NCBI | |
Dawson R Jr, Biasetti M, Messina S and Dominy J: The cytoprotective role of taurine in exercise-induced muscle injury. Amino Acids. 22:309–324. 2002. View Article : Google Scholar : PubMed/NCBI | |
Silva LA, Silveira PC, Ronsani MM, Souza PS, Scheffer D, Vieira LC, Benetti M, De Souza CT and Pinho RA: Taurine supplementation decreases oxidative stress in skeletal muscle after eccentric exercise. Cell Biochem Funct. 29:43–49. 2011. View Article : Google Scholar : PubMed/NCBI | |
Marcinkiewicz J: Taurine bromamine: A new therapeutic option in inflammatory skin diseases. Pol Arch Med Wewn. 119:673–676. 2009.PubMed/NCBI | |
Kato T, Okita S, Wang S, Tsunekawa M and Ma N: The effects of Taurine administration against inflammation in heavily exercised skeletal muscle of rats. Taurine 9. Advances in Experimental Medicine and Biology. Marcinkiewicz J and Schaffer SW: 803. Springer; New York, NY: pp. 773–784. 2015, View Article : Google Scholar : PubMed/NCBI | |
Sugiura H, Okita S, Kato T, Naka T, Kawanishi S, Ohnishi S, Oshida Y and Ma N: Protection by taurine against INOS-dependent DNA damage in heavily exercised skeletal muscle by inhibition of the NF-κB signaling pathway. Taurine 8. Advances in Experimental Medicine and Biology. El Idrissi A and L'Amoreaux WJ: 775. Springer; New York, NY: pp. 237–246. 2013, View Article : Google Scholar : PubMed/NCBI | |
Moyes CD: Controlling muscle mitochondrial content. J Exp Biol. 206:4385–4391. 2003. View Article : Google Scholar : PubMed/NCBI | |
Nikolaidis MG and Mougios V: Effects of exercise on the fatty-acid composition of blood and tissue lipids. Sports Med. 34:1051–1057. 2004. View Article : Google Scholar : PubMed/NCBI | |
Nikolaidis MG, Petridou A and Mougios V: Comparison of the phospholipid and triacylglycerol fatty acid profile of rat serum, skeletal muscle and heart. Physiol Res. 55:259–265. 2006.PubMed/NCBI | |
Imagawa TF, Hirano I, Utsuki K, Horie M, Naka A, Matsumoto K and Imagawa S: Caffeine and taurine enhance endurance performance. Int J Sports Med. 30:485–488. 2009. View Article : Google Scholar : PubMed/NCBI | |
Mikami N, Hosokawa M and Miyashita K: Dietary combination of fish oil and taurine decreases fat accumulation and ameliorates blood glucose levels in type 2 diabetic/obese KK-A(y) mice. J Food Sci. 77:H114–H120. 2012. View Article : Google Scholar : PubMed/NCBI | |
Ra SG, Miyazaki T, Ishikura K, Nagayama H, Komine S, Nakata Y, Maeda S, Matsuzaki Y and Ohmori H: Combined effect of branched-chain amino acids and taurine supplementation on delayed onset muscle soreness and muscle damage in high-intensity eccentric exercise. J Int Soc Sports Nutr. 10:512013. View Article : Google Scholar : PubMed/NCBI | |
Galloway SD, Talanian JL, Shoveller AK, Heigenhauser GJ and Spriet LL: Seven days of oral taurine supplementation does not increase muscle taurine content or alter substrate metabolism during prolonged exercise in humans. J Appl Physiol (1985). 105:643–651. 2008. View Article : Google Scholar : PubMed/NCBI | |
D'Antona G, Nabavi SM, Micheletti P, Di Lorenzo A, Aquilani R, Nisoli E, Rondanelli M and Daglia M: Creatine, L-carnitine, and ω3 polyunsaturated fatty acid supplementation from healthy to diseased skeletal muscle. Biomed Res Int. 2014:6138902014. | |
Rutherford JA, Spriet LL and Stellingwerff T: The effect of acute taurine ingestion on endurance performance and metabolism in well-trained cyclists. Int J Sport Nutr Exerc Metab. 20:322–329. 2010. View Article : Google Scholar : PubMed/NCBI | |
Balshaw TG, Bampouras TM, Barry TJ and Sparks SA: The effect of acute taurine ingestion on 3-km running performance in trained middle-distance runners. Amino Acids. 44:555–561. 2013. View Article : Google Scholar : PubMed/NCBI | |
da Silva LA, Tromm CB, Bom KF, Mariano I, Pozzi B, da Rosa GL, Tuon T, da Luz G, Vuolo F, Petronilho F, et al: Effects of taurine supplementation following eccentric exercise in young adults. Appl Physiol Nutr Metab. 39:101–104. 2014. View Article : Google Scholar : PubMed/NCBI | |
Ra SG, Choi Y, Akazawa N, Kawanaka K, Ohmori H and Maeda S: Effects of taurine supplementation on vascular endothelial function at rest and after resistance exercise. Taurine 11. Advances in Experimental Medicine and Biology. Hu J, Piao F, Schaffer SW, El Idrissi A and Wu JY: 1155. Springer; Singapore: pp. 407–414. 2019, View Article : Google Scholar : PubMed/NCBI | |
Zhang M, Izumi I, Kagamimori S, Sokejima S, Yamagami T, Liu Z and Qi B: Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Amino Acids. 26:203–207. 2004. View Article : Google Scholar : PubMed/NCBI | |
Chupel MU, Minuzzi LG, Furtado GE, Santos ML, Ferreira JP, Filaire E and Teixeira AM: Taurine supplementation reduces myeloperoxidase and matrix-metalloproteinase-9 levels and improves the effects of exercise in cognition and physical fitness in older women. Amino Acids. 53:333–435. 2021. View Article : Google Scholar : PubMed/NCBI | |
De Paepe B, Martin JJ, Herbelet S, Jimenez-Mallebrera C, Iglesias E, Jou C, Weis J and De Bleecker JL: Activation of osmolyte pathways in inflammatory myopathy and Duchenne muscular dystrophy points to osmoregulation as a contributing pathogenic mechanism. Lab Invest. 96:872–884. 2016. View Article : Google Scholar : PubMed/NCBI | |
Pierno S, Liantonio A, Camerino GM, De Bellis M, Cannone M, Gramegna G, Scaramuzzi A, Simonetti S, Nicchia GP, Basco D, et al: Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat. Amino Acids. 43:431–445. 2012. View Article : Google Scholar : PubMed/NCBI | |
Uozumi Y, Ito T, Hoshino Y, Mohri T, Maeda M, Takahashi K, Fujio Y and Azuma J: Myogenic differentiation induces taurine transporter in association with taurine-mediated cytoprotection in skeletal muscles. Biochem J. 394:699–706. 2006. View Article : Google Scholar : PubMed/NCBI | |
Terrill JR, Grounds MD and Arthur PG: Taurine deficiency, synthesis and transport in the mdx mouse model for Duchenne muscular dystrophy. Int J Biochem Cell Biol. 66:141–148. 2015. View Article : Google Scholar : PubMed/NCBI | |
Cozzoli A, Nico B, Sblendorio VT, Capogrosso RF, Dinardo MM, Longo V, Gagliardi S, Montagnani M and De Luca A: Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice. Pharmacol Res. 64:482–492. 2011. View Article : Google Scholar : PubMed/NCBI | |
Jaeschke H: Reactive oxygen and mechanisms of inflammatory liver injury. J Gastroenterol Hepatol. 15:718–724. 2000. View Article : Google Scholar : PubMed/NCBI | |
Warskulat U, Borsch E, Reinehr R, Heller-Stilb B, Mönnighoff I, Buchczyk D, Donner M, Flögel U, Kappert G, Soboll S, et al: Chronic liver disease is triggered by taurine transporter knockout in the mouse. FASEB J. 20:574–576. 2006. View Article : Google Scholar : PubMed/NCBI | |
Chen X, Sebastian BM, Tang H, McMullen MM, Axhemi A, Jacobsen DW and Nagy LE: Taurine supplementation prevents ethanol-induced decrease in serum adiponectin and reduces hepatic steatosis in rats. Hepatology. 49:1554–1562. 2009. View Article : Google Scholar : PubMed/NCBI | |
Goc Z, Kapusta E, Formicki G, Martiniaková M and Omelka R: Effect of taurine on ethanol-induced oxidative stress in mouse liver and kidney. Chin J Physiol. 62:148–156. 2019. View Article : Google Scholar : PubMed/NCBI | |
Lin CJ, Chiu CC, Chen YC, Chen ML, Hsu TC and Tzang BS: Taurine attenuates hepatic inflammation in chronic alcohol-fed rats through inhibition of TLR4/MyD88 signaling. J Med Food. 18:1291–1298. 2015. View Article : Google Scholar : PubMed/NCBI | |
Murakami S, Ono A, Kawasaki A, Takenaga T and Ito T: Taurine attenuates the development of hepatic steatosis through the inhibition of oxidative stress in a model of nonalcoholic fatty liver disease in vivo and in vitro. Amino Acids. 50:1279–1288. 2018. View Article : Google Scholar : PubMed/NCBI | |
Zhang Z, Liu D, Yi B, Liao Z, Tang L, Yin D and He M: Taurine supplementation reduces oxidative stress and protects the liver in an iron-overload murine model. Mol Med Rep. 10:2255–2262. 2014. View Article : Google Scholar : PubMed/NCBI | |
Choi MJ and Jung YJ: Effects of taurine and vitamin d on antioxidant enzyme activity and lipids profiles in rats fed diet deficient calcium. Taurine 10. Advances in Experimental Medicine and Biology. Lee DH, Schaffer SW, Park E and Kim HW: 975. Springer; Dordrecht: pp. 1081–1092. 2017, View Article : Google Scholar : PubMed/NCBI | |
Abdel-Daim MM, Dessouki AA, Abdel-Rahman HG, Eltaysh R and Alkahtani S: Hepatorenal protective effects of taurine and N-acetylcysteine against fipronil-induced injuries: The antioxidant status and apoptotic markers expression in rats. Sci Total Environ. 650:2063–2073. 2019. View Article : Google Scholar : PubMed/NCBI | |
Hoang MH, Jia Y, Jun H, Lee JH, Hwang KY, Choi DW, Um SJ, Lee BY, You SG and Lee SJ: Taurine is a liver X receptor-α ligand and activates transcription of key genes in the reverse cholesterol transport without inducing hepatic lipogenesis. Mol Nutr Food Res. 56:900–911. 2012. View Article : Google Scholar : PubMed/NCBI | |
Geyeregger R, Zeyda M and Stulnig TM: Liver X receptors in cardiovascular and metabolic disease. Cell Mol Life. 63:524–539. 2006. View Article : Google Scholar : PubMed/NCBI | |
Cao PJ, Jin YJ, Li ME, Zhou R and Yang MZ: PGC-1α may associated with the anti-obesity effect of taurine on rats induced by arcuate nucleus lesion. Nutr Neurosci. 19:86–93. 2016. View Article : Google Scholar : PubMed/NCBI | |
Mizushima S, Nara Y, Sawamura M and Yamori Y: Effects of oral taurine supplementation on lipids and sympathetic nerve tone. Taurine 2. Advances in Experimental Medicine and Biology. Huxtable RJ, Azuma J, Kuriyama K, Nakagawa M and Baba A: 403. Springer; Boston, MA: pp. 615–622. 1996, View Article : Google Scholar : PubMed/NCBI | |
Zhang M, Bi LF, Fang JH, Su XL, Da GL, Kuwamori T and Kagamimori S: Beneficial effects of taurine on serum lipids in overweight or obese non-diabetic subjects. Amino Acids. 26:267–271. 2004. View Article : Google Scholar : PubMed/NCBI | |
Miyazaki T, Karube M, Matsuzaki Y, Ikegami T, Doy M, Tanaka N and Bouscarel B: Taurine inhibits oxidative damage and prevents fibrosis in carbon tetrachloride-induced hepatic fibrosis. J Hepatol. 43:117–125. 2005. View Article : Google Scholar : PubMed/NCBI | |
Abd-Elhakim YM, Ghoneim MH, Ebraheim LLM and Imam TS: Taurine and hesperidin rescues carbon tetrachloride-triggered testicular and kidney damage in rats via modulating oxidative stress and inflammation. Life Sci. 254:1177822020. View Article : Google Scholar : PubMed/NCBI | |
Burlacu A, Genovesi S, Ortiz A, Combe C, Basile C, Schneditz D, van der Sande F, Popa GT, Morosanu C and Covic A: Pros and cons of antithrombotic therapy in end-stage kidney disease: A 2019 update. Nephrol Dial Transplant. 34:923–933. 2019. View Article : Google Scholar : PubMed/NCBI | |
Ijiri Y, Ikarugi H, Tamura Y, Ura M, Morishita M, Hamada A, Mori M, Mori H, Yamori Y, Ishii H and Yamamoto J: Antithrombotic effect of taurine in healthy Japanese people may be related to an increased endogenous thrombolytic activity. Thromb Res. 131:158–161. 2013. View Article : Google Scholar : PubMed/NCBI | |
Lee WM: Acetaminophen toxicity: Changing perceptions on a social/medical issue. Hepatology. 46:966–970. 2007. View Article : Google Scholar : PubMed/NCBI | |
Bessems JG and Vermeulen NP: Paracetamol (acetaminophen)-induced toxicity: Molecular and biochemical mechanisms, analogues and protective approaches. Crit Rev Toxicol. 31:55–138. 2001. View Article : Google Scholar : PubMed/NCBI | |
Jaeschke H, Knight TR and Bajt ML: The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity. Toxicol Lett. 144:279–288. 2003. View Article : Google Scholar : PubMed/NCBI | |
Hinson JA, Roberts DW and James LP: Mechanisms of acetaminophen-induced liver necrosis. Adverse Drug Reactions. Handbook of Experimental Pharmacology. Uetrecht J: 196. Springer; Berlin: pp. 369–405. 2010, View Article : Google Scholar : PubMed/NCBI | |
Acharya M and Lau-Cam CA: Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat. J Biomed Sci. 17 (Suppl 1):S352010. View Article : Google Scholar : PubMed/NCBI | |
Acharya M and Lau-Cam CA: Comparative evaluation of the effects of taurine and thiotaurine on alterations of the cellular redox status and activities of antioxidant and glutathione-related enzymes by acetaminophen in the rat. Taurine 8. Advances in Experimental Medicine and Biology. El Idrissi A and L'Amoreaux WJ: 776. Springer; New York, NY: pp. 199–215. 2013, View Article : Google Scholar : PubMed/NCBI | |
Ghandforoush-Sattari M and Mashayekhi S: Evaluation of taurine as a biomarker of liver damage in paracetamol poisoning. Eur J Pharmacol. 581:171–176. 2008. View Article : Google Scholar : PubMed/NCBI | |
Boşgelmez İİ, Söylemezoğlu T and Güvendik G: The protective and antidotal effects of taurine on hexavalent chromium-induced oxidative stress in mice liver tissue. Biol Trace Elem Res. 125:46–58. 2008. View Article : Google Scholar | |
Tabassum H, Rehman H, Banerjee BD, Raisuddin S and Parvez S: Attenuation of tamoxifen-induced hepatotoxicity by taurine in mice. Clin Chim Acta. 370:129–136. 2006. View Article : Google Scholar : PubMed/NCBI | |
Patrick L: Lead toxicity part II: The role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity. Altern Med Rev. 11:114–127. 2006.PubMed/NCBI | |
Hwang DF, Wang LC and Cheng HM: Effect of taurine on toxicity of copper in rats. Food Chem Toxicol. 36:239–244. 1998. View Article : Google Scholar : PubMed/NCBI | |
Hwang D and Wang LC: Effect of taurine on toxicity of cadmium in rats. Toxicology. 167:173–180. 2001. View Article : Google Scholar : PubMed/NCBI | |
Jamshidzadeh A, Heidari R, Abasvali M, Zarei M, Ommati MM, Abdoli N, Khodaei F, Yeganeh Y, Jafari F, Zarei A, et al: Taurine treatment preserves brain and liver mitochondrial function in a rat model of fulminant hepatic failure and hyperammonemia. Biomed Pharmacother. 86:514–520. 2017. View Article : Google Scholar : PubMed/NCBI | |
Doğru-Abbasoğlu S, Kanbağli O, Balkan J, Cevikbaş U, Aykaç-Toker G and Uysal M: The protective effect of taurine against thioacetamide hepatotoxicity of rats. Hum Exp Toxicol. 20:23–27. 2001. View Article : Google Scholar | |
Bardach AE, Ciapponi A, Soto N, Chaparro MR, Calderon M, Briatore A, Cadoppi N, Tassara R and Litter MI: Epidemiology of chronic disease related to arsenic in Argentina: A systematic review. Sci Total Environ. 538:802–816. 2015. View Article : Google Scholar : PubMed/NCBI | |
Li S, Yang L, Dong G and Wang X: Taurine protects mouse liver against arsenic-induced apoptosis through JNK pathway. Taurine 10. Advances in Experimental Medicine and Biology. Lee DH, Schaffer SW, Park E and Kim HW: 975. Springer; Dordrecht: pp. 855–862. 2017, View Article : Google Scholar : PubMed/NCBI | |
Taranukhin AG, Taranukhina EY, Saransaari P, Pelto-Huikko M, Podkletnova IM and Oja SS: Taurine protects cerebellar neurons of the external granular layer against ethanol-induced apoptosis in 7-day-old mice. Amino Acids. 43:1705–1711. 2012. View Article : Google Scholar : PubMed/NCBI | |
Lau A, Zheng Y, Tao S, Wang H, Whitman SA, White E and Zhang DD: Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner. Mol Cell Biol. 33:2436–2446. 2013. View Article : Google Scholar : PubMed/NCBI | |
Bai J, Yao X, Jiang L, Zhang Q, Guan H, Liu S, Wu W, Qiu T, Gao N, Yang L, et al: Taurine protects against As2O3-induced autophagy in livers of rat offsprings through PPARγ pathway. Sci Rep. 6:277332016. View Article : Google Scholar : PubMed/NCBI | |
Qiu T, Pei P, Yao X, Jiang L, Wei S, Wang Z, Bai J, Yang G, Gao N, Yang L, et al: Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway. Cell Death Dis. 9:9462018. View Article : Google Scholar : PubMed/NCBI | |
Flora SJS, Chouhan S, Kannan GM, Mittal M and Swarnkar H: Combined administration of taurine and monoisoamyl DMSA protects arsenic induced oxidative injury in rats. Oxid Med Cell Longev. 1:39–45. 2008. View Article : Google Scholar : PubMed/NCBI | |
Cao W, Zhou Y, Li Y, Zhang X, He M, Zang N, Zhou Y and Liao M: iTRAQ-based proteomic analysis of combination therapy with taurine, epigallocatechin gallate, and genistein on carbon tetrachloride-induced liver fibrosis in rats. Toxicol Lett. 232:233–245. 2015. View Article : Google Scholar : PubMed/NCBI | |
El-Houseini ME, El-Agoza IA, Sakr MM and El-Malky GM: Novel protective role of curcumin and taurine combination against experimental hepatocarcinogenesis. Exp Ther Med. 13:29–36. 2017. View Article : Google Scholar : PubMed/NCBI | |
Abd-Rabou AA, Zoheir KMA and Ahmed HH: Potential impact of curcumin and taurine on human hepatoma cells using Huh-7 cell line. Clin Biochem. 45:1519–1521. 2012. View Article : Google Scholar : PubMed/NCBI | |
Pan MH, Yang G, Li S, Li MY, Tsai ML, Wu JC, Badmaev V, Ho CT and Lai CS: Combination of citrus polymethoxyflavones, green tea polyphenols, and Lychee extracts suppresses obesity and hepatic steatosis in high-fat diet induced obese mice. Mol Nutr Food Res. 61:2017. View Article : Google Scholar | |
Balkan J, Kanbagli Ö, Hatipoglu A, Küçük M, Çevikbas U, Aykaç-Toker G and Uysal M: Improving effect of dietary taurine supplementation on the oxidative stress and lipid levels in the plasma, liver and aorta of rabbits fed on a high-cholesterol diet. Biosci Biotechnol Biochem. 66:1755–1758. 2002. View Article : Google Scholar : PubMed/NCBI | |
Cetiner M, Sener G, Sehirli AO, Ekşioğlu-Demiralp E, Ercan F, Sirvanci S, Gedik N, Akpulat S, Tecimer T and Yeğen BC: Taurine protects against methotrexate-induced toxicity and inhibits leukocyte death. Toxicol Appl Pharmacol. 209:39–50. 2005. View Article : Google Scholar : PubMed/NCBI | |
Kalaz EB, Çoban J, Aydın AF, Doğan-Ekici I, Doğru- Abbasoğlu S, Öztezcan S and Uysal M: Carnosine and taurine treatments decreased oxidative stress and tissue damage induced by D-galactose in rat liver. J Physiol Biochem. 70:15–25. 2014. View Article : Google Scholar : PubMed/NCBI | |
Shi X, Yao D and Chen C: Identification of N-acetyltaurine as a novel metabolite of ethanol through metabolomics-guided biochemical analysis. J Biol Chem. 287:6336–6349. 2012. View Article : Google Scholar : PubMed/NCBI | |
Heidari R, Babaei H and Eghbal MA: Amodiaquine-induced toxicity in isolated rat hepatocytes and the cytoprotective effects of taurine and/or N-acetyl cysteine. Res Pharm Sci. 9:97–105. 2014.PubMed/NCBI | |
Timbrell JA and Waterfield CJ: Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations. Taurine 2. Advances in Experimental Medicine and Biology. Huxtable RJ, Azuma J, Kuriyama K, Nakagawa M and Baba A: 403. Springer; Boston, MA: pp. 125–134. 1996, View Article : Google Scholar : PubMed/NCBI | |
Gordon RE, Park E, Laskin D and Schuller-Levis GB: Taurine protects rat bronchioles from acute ozone exposure: A freeze fracture and electron microscopic study. Exp Lung Res. 24:659–674. 1998. View Article : Google Scholar : PubMed/NCBI | |
Venkatachalam S, Kuppusamy P, Kuppusamy B and Dhanapal S: The potency of essential nutrient taurine on boosting the antioxidant status and chemopreventive effect against benzo (a)pyrene induced experimental lung cancer. Biomed Prev Nutr. 4:251–255. 2014. View Article : Google Scholar | |
Gurujeyalakshmi G, Wang Y and Giri SN: Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin. Nitric Oxide. 4:399–411. 2000. View Article : Google Scholar : PubMed/NCBI | |
Wang Q, Hollinger MA and Giri SN: Attenuation of amiodarone-induced lung fibrosis and phospholipidosis in hamsters by taurine and/or niacin treatment. J Pharmacol Exp Ther. 262:127–132. 1992.PubMed/NCBI | |
Izumi K, Nagata R, Motoya T, Yamashita J, Hirokane T, Nagata T, Satoh Y, Sawada Y, Ishibashi M, Yoshida H, et al: Preventive effect of taurine against acute paraquat intoxication in beagles. Jpn J Pharmacol. 50:229–233. 1989. View Article : Google Scholar : PubMed/NCBI | |
Li S, Wang J, Wei BK, Dong G and Wang X: Protective effect of taurine on paraquat-induced lung epithelial cell injury. Taurine 11. Advances in Experimental Medicine and Biology. Hu J, Piao F, Schaffer SW, El Idrissi A and Wu JY: 1155. Springer; Singapore: pp. 739–746. 2019, View Article : Google Scholar : PubMed/NCBI | |
Khalili Fard J, Hamzeiy H, Sattari M and Eghbal MA: Protective roles of N-acetyl cysteine and/or taurine against sumatriptan-induced hepatotoxicity. Adv Pharm Bull. 6:627–637. 2016. View Article : Google Scholar : PubMed/NCBI | |
Gordon RE, Shaked AA and Solano DF: Taurine protects hamster bronchioles from acute NO2-induced alterations. A histologic, ultrastructural, and freeze-fracture study. Am J Pathol. 125:585–600. 1986.PubMed/NCBI | |
Jeon SH, Lee MY, Rahman MM, Kim SJ, Kim GB, Park SY, Hong CU, Kim SZ, Kim JS and Kang HS: The antioxidant, taurine reduced lipopolysaccharide (LPS)-induced generation of ROS, and activation of MAPKs and Bax in cultured pneumocytes. Pulm Pharmacol Ther. 22:562–566. 2009. View Article : Google Scholar : PubMed/NCBI | |
Das J, Ghosh J, Manna P, Sinha M and Sil PC: Taurine protects rat testes against NaAsO(2)-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways. Toxicol Lett. 187:201–210. 2009. View Article : Google Scholar : PubMed/NCBI | |
Meizel S: Molecules that initiate or help stimulate the acrosome reaction by their interaction with the mammalian sperm surface. Am J Anat. 174:285–302. 1985. View Article : Google Scholar : PubMed/NCBI | |
Aly HA and Khafagy RM: Taurine reverses endosulfan-induced oxidative stress and apoptosis in adult rat testis. Food Chem Toxicol. 64:1–9. 2014. View Article : Google Scholar : PubMed/NCBI | |
Azab SS, kamel I, Ismail NN, El Din Hosni H and El Fatah MA: The defensive role of taurine against gonadotoxicity and testicular apoptosis effects induced by cisplatin in rats. J Infect Chemother. 26:51–57. 2020. View Article : Google Scholar : PubMed/NCBI | |
Yahyavy S, Valizadeh A, Saki G and Khorsandi L: Taurine induces autophagy and inhibits oxidative stress in mice Leydig cells. JBRA Assist Reprod. 24:250–256. 2020.PubMed/NCBI | |
Kalender S, Apaydin FG and Kalender Y: Testicular toxicity of orally administrated bisphenol A in rats and protective role of taurine and curcumin. Pak J Pharm Sci. 32:1043–1047. 2019.PubMed/NCBI |