Open Access

Radioprotective countermeasures for radiation injury (Review)

  • Authors:
    • Lianchang Liu
    • Zhenzhen Liang
    • Shumei Ma
    • Lan Li
    • Xiaodong Liu
  • View Affiliations

  • Published online on: February 6, 2023     https://doi.org/10.3892/mmr.2023.12953
  • Article Number: 66
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

A series of physiological and pathological changes occur after radiotherapy and accidental exposure to ionizing radiation (IR). These changes cause serious damage to human tissues and can lead to death. Radioprotective countermeasures are radioprotective agents that prevent and reduce IR injury or have therapeutic effects. Based on a good understanding of radiobiology, a number of protective agents have achieved positive results in early clinical trials. The present review grouped known radioprotective agents according to biochemical categories and potential clinical use, and reviewed radiation countermeasures, i.e., radioprotectors, radiation mitigators and radiotherapeutic agents, with an emphasis on their current status and research progress. The aim of the present review is to facilitate the selection and application of suitable radioprotectors for clinicians and researchers, to prevent or reduce IR injury.
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March-2023
Volume 27 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Liu L, Liang Z, Ma S, Li L and Liu X: Radioprotective countermeasures for radiation injury (Review). Mol Med Rep 27: 66, 2023.
APA
Liu, L., Liang, Z., Ma, S., Li, L., & Liu, X. (2023). Radioprotective countermeasures for radiation injury (Review). Molecular Medicine Reports, 27, 66. https://doi.org/10.3892/mmr.2023.12953
MLA
Liu, L., Liang, Z., Ma, S., Li, L., Liu, X."Radioprotective countermeasures for radiation injury (Review)". Molecular Medicine Reports 27.3 (2023): 66.
Chicago
Liu, L., Liang, Z., Ma, S., Li, L., Liu, X."Radioprotective countermeasures for radiation injury (Review)". Molecular Medicine Reports 27, no. 3 (2023): 66. https://doi.org/10.3892/mmr.2023.12953