1
|
Bray F, Laversanne M, Sung H, Ferlay J,
Siegel RL, Soerjomataram I and Jemal A: Global cancer statistics
2022: GLOBOCAN estimates of incidence and mortality worldwide for
36 cancers in 185 countries. CA Cancer J Clin. 74:229–263. 2024.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Xia C, Dong X, Li H, Cao M, Sun D, He S,
Yang F, Yan X, Zhang S, Li N and Chen W: Cancer statistics in China
and United States, 2022: Profiles, trends, and determinants. Chin
Med J (Engl). 135:584–590. 2022. View Article : Google Scholar : PubMed/NCBI
|
3
|
Tang Z, Wei Y, Liang Y, Zhu X, Tang J, Sun
Y and Zhuang Q: Breast cancer burden among young women from 1990 to
2021: A global, regional, and national perspective. Eur J Cancer
Prev. Jul 23–2024.(Epub ahead of print). View Article : Google Scholar
|
4
|
Ofri A, Elstner K, Mann GB, Kumar S and
Warrier S: Neoadjuvant chemotherapy in non-metastatic breast
cancer: The surgeon's perspective. Surgeon. 21:356–360. 2023.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Dou T, Li J, Zhang Y, Pei W, Zhang B, Wang
B, Wang Y and Jia H: The cellular composition of the tumor
microenvironment is an important marker for predicting therapeutic
efficacy in breast cancer. Front Immunol. 15:13686872024.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Bimonte S, Cascella M, Barbieri A, Arra C
and Cuomo A: Current shreds of evidence on the anticancer role of
EGCG in triple negative breast cancer: An update of the current
state of knowledge. Infect Agent Cancer. 15:22020. View Article : Google Scholar : PubMed/NCBI
|
7
|
Li W, Song K, Wang S, Zhang C, Zhuang M,
Wang Y and Liu T: Anti-tumor potential of astragalus
polysaccharides on breast cancer cell line mediated by macrophage
activation. Mater Sci Eng C Mater Biol Appl. 98:685–695. 2019.
View Article : Google Scholar : PubMed/NCBI
|
8
|
Adinew GM, Taka E, Mochona B, Badisa RB,
Mazzio EA, Elhag R and Soliman KFA: Therapeutic potential of
thymoquinone in triple-negative breast cancer prevention and
progression through the modulation of the tumor microenvironment.
Nutrients. 14:792021. View Article : Google Scholar : PubMed/NCBI
|
9
|
Guan L, Zheng Z, Guo Z, Xiao S, Liu T,
Chen L, Gao H and Wang Z: Steroidal saponins from rhizome of
Paris polyphylla var. chinensis and their anti-inflammatory,
cytotoxic effects. Phytochemistry. 219:1139942024. View Article : Google Scholar : PubMed/NCBI
|
10
|
Gao XM, Wang X, Ma WS, Yang Y, Tang LP and
Yang B: Comparative metabolome profiling of Paris polyphylla
var. yunnanensis cultivars and Paris luquanensis and their
biological activity in zebrafish model. J Ethnopharmacol.
319:1172722024. View Article : Google Scholar : PubMed/NCBI
|
11
|
Li L, Zhang J, Cheng W, Di F, Wang C and
An Q: Saponins of Paris polyphylla for the improvement of
acne: Anti-inflammatory, antibacterial, antioxidant and
immunomodulatory effects. Molecules. 29:17932024. View Article : Google Scholar : PubMed/NCBI
|
12
|
Luo B, Yang M, Han Z, Que Z, Luo T and
Tian J: Establishment of a nomogram-based prognostic model
(LASSO-COX regression) for predicting progression-free survival of
primary non-small cell lung cancer patients treated with adjuvant
chinese herbal medicines therapy: A retrospective study of case
series. Front Oncol. 12:8822782022. View Article : Google Scholar : PubMed/NCBI
|
13
|
Wang YH, Shi M, Niu HM, Yang J, Xia MY,
Luo JF, Chen YJ, Zhou YP and Li H: Substituting one Paris for
another? In vitro cytotoxic and in vivo antitumor activities of
Paris forrestii, a substitute of Paris polyphylla var.
yunnanensis. J Ethnopharmacol. 218:45–50. 2018. View Article : Google Scholar : PubMed/NCBI
|
14
|
Liu Z, Sun Z, Zhang D, Ma C, Jiang Y, Cao
G, Sun C, Li K, Xu D, Liu J and Zhao S: Paris polyphylla
ethanol extract induces G2/M arrest and suppresses migration and
invasion in bladder cancer. Transl Cancer Res. 9:5994–6004. 2020.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Li HL, Yan CP, Qi JS, Zhang S, Guo DQ, Gu
WC, Wu YM, Wu Y and Zhou N: Analysis of the heavy metal contents'
effect on steroidal saponins and the anti-breast cancer activity of
Paris polyphylla var. yunnanensis. Front Pharmacol.
14:12773952023. View Article : Google Scholar : PubMed/NCBI
|
16
|
Bach TS, La VH, Khoi TX, Nguyen DH, Cuong
CB and Nguyen TV: Identification, phytochemistry and biological
activities of Paris polyphylla on hepatocellular carcinoma.
Pak J Biol Sci. 26:203–212. 2023. View Article : Google Scholar : PubMed/NCBI
|
17
|
Kshetrimayum V, Heisnam R, Keithellakpam
OS, Radhakrishnanand P, Akula SJ, Mukherjee PK and Sharma N:
Paris polyphylla Sm. induces reactive oxygen species and
caspase 3-mediated apoptosis in colorectal cancer cells in vitro
and potentiates the therapeutic significance of fluorouracil and
cisplatin. Plants (Basel). 12:14462023.PubMed/NCBI
|
18
|
Li J, Jia J, Zhu W, Chen J, Zheng Q and Li
D: Therapeutic effects on cancer of the active ingredients in
rhizoma paridis. Front Pharmacol. 14:10957862023. View Article : Google Scholar : PubMed/NCBI
|
19
|
Yu X, Xia K, Wu S, Wang Q, Cheng W, Ji C,
Yang W, Kang C, Yuan Z and Li Y: Simultaneous determination and
pharmacokinetic study of six components in beagle dog plasma by
UPLC-MS/MS after oral administration of astragalus membranaceus
aqueous extract. Biomed Chromatogr. 36:e54882022. View Article : Google Scholar : PubMed/NCBI
|
20
|
Zhang Q, Chang S, Yang Y, Xi C, Dong Y,
Liu L, He Y, Liu Y, Cai B and Liu T: Endophyte-inoculated rhizomes
of Paris polyphylla improve polyphyllin biosynthesis and
yield: A transcriptomic analysis of the underlying mechanism. Front
Microbiol. 14:12611402023. View Article : Google Scholar : PubMed/NCBI
|
21
|
Liu X, Ouyang S, Yu B, Liu Y, Huang K,
Gong J, Zheng S, Li Z, Li H and Jiang H: PharmMapper server: A web
server for potential drug target identification using pharmacophore
mapping approach. Nucleic Acids Res. 38((Web Server Issue)):
W609–W614. 2010. View Article : Google Scholar : PubMed/NCBI
|
22
|
Wang X, Shen Y, Wang S, Li S, Zhang W, Liu
X, Lai L, Pei J and Li H: PharmMapper 2017 update: A web server for
potential drug target identification with a comprehensive target
pharmacophore database. Nucleic Acids Res. 45((W1)): W356–W360.
2017. View Article : Google Scholar : PubMed/NCBI
|
23
|
Hollands C: The animals (scientific
procedures) Act 1986. Lancet. 2:32–33. 1986. View Article : Google Scholar : PubMed/NCBI
|
24
|
Sheng SQ, Yu LY, Zhou XW, Pan HY, Hu FY
and Liu JL: Paeonol prevents migration and invasion, and promotes
apoptosis of cervical cancer cells by inhibiting 5-lipoxygenase.
Mol Med Rep. 23:4012021. View Article : Google Scholar : PubMed/NCBI
|
25
|
Tian Y, Gong GY, Ma LL, Wang ZQ, Song D
and Fang MY: Anti-cancer effects of polyphyllin I: An update in 5
years. Chem Biol Interact. 316:1089362020. View Article : Google Scholar : PubMed/NCBI
|
26
|
Wang W, Dong X, You L, Sai N, Leng X, Yang
C, Yin X and Ni J: Apoptosis in HepaRG and HL-7702 cells inducted
by polyphyllin II through caspases activation and cell-cycle
arrest. J Cell Physiol. 234:7078–7089. 2019. View Article : Google Scholar : PubMed/NCBI
|
27
|
Zhou Y, Yang J, Chen C, Li Z, Chen Y,
Zhang X, Wang L and Zhou J: Polyphyllin III-induced ferroptosis in
MDA-MB-231 triple-negative breast cancer cells can be protected
against by KLF4-mediated upregulation of xCT. Front Pharmacol.
12:6702242021. View Article : Google Scholar : PubMed/NCBI
|
28
|
Liu Y, Zhang W, Zhou H and Chen J:
Steroidal saponins PPI/CCRIS/PSV induce cell death in pancreatic
cancer cell through GSDME-dependent pyroptosis. Biochem Biophys Res
Commun. 673:51–58. 2023. View Article : Google Scholar : PubMed/NCBI
|
29
|
Yuan YL, Jiang N, Li ZY, Song ZZ, Yang ZH,
Xue WH, Zhang XJ and Du Y: Polyphyllin VI induces apoptosis and
autophagy in human osteosarcoma cells by modulation of ROS/JNK
activation. Drug Des Devel Ther. 13:3091–3103. 2019. View Article : Google Scholar : PubMed/NCBI
|
30
|
Wang M, Yuan C, Wu Z, Xu M, Chen Z, Yao J,
Que Z, Tian J, Leung ELHL and Wang Z: Paris saponin VII reverses
resistance to PARP inhibitors by regulating ovarian cancer tumor
angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling
axis. Int J Biol Sci. 20:2454–2475. 2024. View Article : Google Scholar : PubMed/NCBI
|
31
|
Bi L, Liu Y, Yang Q, Zhou X, Li H, Liu Y,
Li J, Lu Y and Tang H: Paris saponin H inhibits the proliferation
of glioma cells through the A1 and A3 adenosine receptor-mediated
pathway. Int J Mol Med. 47:302021. View Article : Google Scholar : PubMed/NCBI
|
32
|
Li JK, Zhu PL, Wang Y, Jiang XL, Zhang Z,
Zhang Z and Yung KKL: Gracillin exerts anti-melanoma effects in
vitro and in vivo: Role of DNA damage, apoptosis and autophagy.
Phytomedicine. 108:1545262023. View Article : Google Scholar : PubMed/NCBI
|
33
|
He Y, Sun MM, Zhang GG, Yang J, Chen KS,
Xu WW and Li B: Targeting PI3K/Akt signal transduction for cancer
therapy. Signal Transduct Target Ther. 6:4252021. View Article : Google Scholar : PubMed/NCBI
|
34
|
Lv S, Dai W, Zheng Y, Dong P, Yu Y, Zhao
Y, Sun S, Bi D, Liu C, Han F, et al: Anxiolytic effect of
YangshenDingzhi granules: Integrated network pharmacology and
hippocampal metabolomics. Front Pharmacol. 13:9662182022.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Chinese Pharmacopoeia Commission:
Pharmacopoeia of the People's Republic of China (2020 edition).
China Medical Science Press, Beijing, China. volume 1:2712020.(In
Chinese).
|
36
|
Cheng H, Chu J, Yang Y, Li Y, Wang M, Wu
H, Wang M, Su J and Li Q: Paris polyphylla saponins II
inhibits invasive, migration and epithelial-mesenchymal transition
of melanoma cells through activation of autophagy. Toxicon.
237:1075582024. View Article : Google Scholar : PubMed/NCBI
|
37
|
Qi W, Zhu F, Wang M, Teng Z, Xu R, Xi Y,
Meng Q, Wu X, Zhao H, Ma M, et al: The antitumoral effect of paris
saponin ii on head and neck squamous cell carcinomas mediated via
the nitric oxide metabolic pathway. Front Cell Dev Biol.
9:8039812022. View Article : Google Scholar : PubMed/NCBI
|
38
|
Pang D, Yang C, Li C, Zou Y, Feng B, Li L,
Liu W, Luo Q, Chen Z and Huang C: Polyphyllin II inhibits liver
cancer cell proliferation, migration and invasion through
downregulated cofilin activity and the AKT/NF-κB pathway. Biol
Open. 9:bio0468542020. View Article : Google Scholar : PubMed/NCBI
|
39
|
Man S, Lv P, Cui J, Liu F, Peng L, Ma L,
Liu C and Gao W: Paris saponin II-induced paraptosis-associated
cell death increased the sensitivity of cisplatin. Toxicol Appl
Pharmacol. 406:1152062020. View Article : Google Scholar : PubMed/NCBI
|
40
|
Niu W, Xu L, Li J, Zhai Y, Sun Z, Shi W,
Jiang Y, Ma C, Lin H, Guo Y and Liu Z: Polyphyllin II inhibits
human bladder cancer migration and invasion by regulating
EMT-associated factors and MMPs. Oncol Lett. 20:2928–2936. 2020.
View Article : Google Scholar : PubMed/NCBI
|
41
|
Chen M, Ye K, Zhang B, Xin Q, Li P, Kong
AN, Wen X and Yang J: Paris saponin II inhibits colorectal
carcinogenesis by regulating mitochondrial fission and NF-κB
pathway. Pharmacol Res. 139:273–285. 2019. View Article : Google Scholar : PubMed/NCBI
|
42
|
Zhu K, Wu Y, He P, Fan Y, Zhong X, Zheng H
and Luo T: PI3K/AKT/mTOR-targeted therapy for breast cancer. Cells.
11:25082022. View Article : Google Scholar : PubMed/NCBI
|
43
|
Miricescu D, Totan A, Stanescu-Spinu II,
Badoiu SC, Stefani C and Greabu M: PI3K/AKT/mTOR signaling pathway
in breast cancer: From molecular landscape to clinical aspects. Int
J Mol Sci. 22:1732020. View Article : Google Scholar : PubMed/NCBI
|
44
|
Khorasani ABS, Hafezi N, Sanaei MJ,
Jafari-Raddani F, Pourbagheri-Sigaroodi A and Bashash D: The
PI3K/AKT/mTOR signaling pathway in breast cancer: Review of
clinical trials and latest advances. Cell Biochem Funct.
42:e39982024. View Article : Google Scholar : PubMed/NCBI
|
45
|
Gao Z, Zhang Y, Shen W, Liu X, Wei Y, Li L
and Cui H: Bruceine A inhibited breast cancer proliferation and
metastasis by inducing autophagy via targeting PI3K-AKT signaling
pathway. Chem Biol Drug Des. 103:e143982024. View Article : Google Scholar : PubMed/NCBI
|
46
|
Wang F, Yuan C, Liu B, Yang YF and Wu HZ:
Syringin exerts anti-breast cancer effects through PI3K-AKT and
EGFR-RAS-RAF pathways. J Transl Med. 20:3102022. View Article : Google Scholar : PubMed/NCBI
|
47
|
Wei J and Wu J, Xu W, Nie H, Zhou R, Wang
R, Liu Y, Tang G and Wu J: Salvianolic acid B inhibits glycolysis
in oral squamous cell carcinoma via targeting PI3K/AKT/HIF-1α
signaling pathway. Cell Death Dis. 9:5992018. View Article : Google Scholar : PubMed/NCBI
|
48
|
Dimri M, Humphries A, Laknaur A, Elattar
S, Lee TJ, Sharma A, Kolhe R and Satyanarayana A: NAD(P)H quinone
dehydrogenase 1 ablation inhibits activation of the
phosphoinositide 3-kinase/Akt serine/threonine kinase and
mitogen-activated protein kinase/extracellular signal-regulated
kinase pathways and blocks metabolic adaptation in hepatocellular
carcinoma. Hepatology. 71:549–568. 2020. View Article : Google Scholar : PubMed/NCBI
|
49
|
Wu Z, Wu J, Zhao Q, Fu S and Jin J:
Emerging roles of aerobic glycolysis in breast cancer. Clin Transl
Oncol. 22:631–646. 2020. View Article : Google Scholar : PubMed/NCBI
|
50
|
Xie S, Li X, Zhao J, Zhang F, Shu Z, Cheng
H, Liu S and Shi S: The effect and mechanism of hexokinase-2 on
cisplatin resistance in lung cancer cells A549. Environ Toxicol.
39:2667–2680. 2024. View Article : Google Scholar : PubMed/NCBI
|
51
|
Alves-Filho JC and Pålsson-McDermott EM:
Pyruvate kinase M2: A potential target for regulating inflammation.
Front Immunol. 7:1452016. View Article : Google Scholar : PubMed/NCBI
|
52
|
Lin J, Fang W, Xiang Z, Wang Q, Cheng H,
Chen S, Fang J, Liu J, Wang Q, Lu Z and Ma L: Glycolytic enzyme HK2
promotes PD-L1 expression and breast cancer cell immune evasion.
Front Immunol. 14:11899532023. View Article : Google Scholar : PubMed/NCBI
|
53
|
Shang XY, Wang YJ, Hou ZL, Wang XY, Zhang
H, Yang CY, Li JC, Huang XX, Song SJ and Yao GD: A natural PKM2
targeting agent as a potential drug for breast cancer treatment.
Clin Transl Med. 13:e11572023. View Article : Google Scholar : PubMed/NCBI
|
54
|
Ganapathy-Kanniappan S: Molecular
intricacies of aerobic glycolysis in cancer: Current insights into
the classic metabolic phenotype. Crit Rev Biochem Mol Biol.
53:667–682. 2018. View Article : Google Scholar : PubMed/NCBI
|