Selective anticancer activity of β-lactams derived from polyaromatic compound

  • Authors:
    • Bimal K. Banik
    • Frederick F. Becker
  • View Affiliations

  • Published online on: March 1, 2010     https://doi.org/10.3892/mmr_00000257
  • Pages: 315-316
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Abstract

Currently available anticancer drugs are cytotoxic to normal as well as to neoplastic cells, therefore the synthesis of β-lactams as new and novel anticancer agents is extremely significant. We previously developed synthetic methods for the preparation of β-lactams and anticancer agents resulting from polyaromatic amines. There have also been reports on the synthesis and biological evaluation of novel racemic β-lactams as anticancer agents. In cell cycle analysis, these compounds demonstrated a G2 blockage against sensitive tumor cell lines. In the present study, useful and selective biological activities of chrysene β-lactams are described.

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March-April 2010
Volume 3 Issue 2

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Spandidos Publications style
Banik BK and Becker FF: Selective anticancer activity of β-lactams derived from polyaromatic compound . Mol Med Rep 3: 315-316, 2010.
APA
Banik, B.K., & Becker, F.F. (2010). Selective anticancer activity of β-lactams derived from polyaromatic compound . Molecular Medicine Reports, 3, 315-316. https://doi.org/10.3892/mmr_00000257
MLA
Banik, B. K., Becker, F. F."Selective anticancer activity of β-lactams derived from polyaromatic compound ". Molecular Medicine Reports 3.2 (2010): 315-316.
Chicago
Banik, B. K., Becker, F. F."Selective anticancer activity of β-lactams derived from polyaromatic compound ". Molecular Medicine Reports 3, no. 2 (2010): 315-316. https://doi.org/10.3892/mmr_00000257