Secretory breast carcinoma: A report of three cases and a review of the literature

Lee,Seung  Geun; Jung,Seung  Pil; Lee,Hye  Yoon; Kim,Sinill; Kim,Hoon Yub; Kim,Insun; Bae,Jeoung  Won

doi:10.3892/ol.2014.2213

Secretory breast carcinoma: A report of three cases and a review of the literature

Authors:
- Seung Geun Lee
- Seung Pil Jung
- Hye Yoon Lee
- Sinill Kim
- Hoon Yub Kim
- Insun Kim
- Jeoung Won Bae
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Affiliations: Breast Center, MD Hospital, Seoul, Republic of Korea, Division of Breast and Endocrine Surgery, Department of Surgery, Korea University Hospital, Korea University College of Medicine, Seoul, Republic of Korea, Department of Pathology, Korea University Hospital, Korea University College of Medicine, Seoul, Republic of Korea
Published online on: June 3, 2014 https://doi.org/10.3892/ol.2014.2213
Pages: 683-686

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Abstract

Secretory breast carcinoma is a very rare and distinct subtype of breast cancer, characterized by the presence of intracellular and extracellular secretory material. Secretory breast carcinoma has a good clinical outcome and systemic involvement is rare. The majority of studies of this tumor have been case reports or separate analyses, and due to the rarity of these tumors, it has been difficult to fully elucidate their characteristics and define optimal treatment strategies. To add to the current knowledge of secretory breast carcinoma, the present study reports three cases of secretory breast carcinoma in patients of different ages, and with different hormone receptor statuses and treatment methods. The present study identified that each patient with secretory breast carcinoma may present with different symptoms and clinical characteristics. Therefore, therapeutic options should be selected based on the overall status of the patient and the characteristics of this rare disease.

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