Open Access

Mixed medullary‑follicular thyroid carcinoma: A case report and literature review

  • Authors:
    • Yonghui Wang
    • Dandan Yin
    • Guifang Ren
    • Zhengjiang Wang
    • Fanhua Kong
  • View Affiliations

  • Published online on: August 18, 2023     https://doi.org/10.3892/ol.2023.14015
  • Article Number: 429
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Papillary thyroid cancer (PTC) and medullary thyroid cancer (MTC) originate from follicular and neuroendocrine parafollicular C cells, respectively. PTC and MTC simultaneously exist in tumors containing both MTC and PTC features in a rare condition known as mixed medullary‑follicular thyroid carcinoma (MMFTC). In the present study, a 60‑year‑old female presented with a small mass on the left side of the neck. Ultrasonography indicated a hyperechoic nodule measuring ~11.9x9.7 mm2 in the left lobe of the thyroid gland. The preoperative calcitonin serum value was elevated and total thyroidectomy and bilateral central compartment lymph node dissection was performed. Histological and immunohistochemical analysis of the tumor demonstrated MMFTC. No metastasis was observed in lymph nodes isolated from the bilateral central compartment. Given the rarity of MMFTC, enhancing understanding and management of such tumors is crucial.
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October-2023
Volume 26 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Wang Y, Yin D, Ren G, Wang Z and Kong F: Mixed medullary‑follicular thyroid carcinoma: A case report and literature review. Oncol Lett 26: 429, 2023.
APA
Wang, Y., Yin, D., Ren, G., Wang, Z., & Kong, F. (2023). Mixed medullary‑follicular thyroid carcinoma: A case report and literature review. Oncology Letters, 26, 429. https://doi.org/10.3892/ol.2023.14015
MLA
Wang, Y., Yin, D., Ren, G., Wang, Z., Kong, F."Mixed medullary‑follicular thyroid carcinoma: A case report and literature review". Oncology Letters 26.4 (2023): 429.
Chicago
Wang, Y., Yin, D., Ren, G., Wang, Z., Kong, F."Mixed medullary‑follicular thyroid carcinoma: A case report and literature review". Oncology Letters 26, no. 4 (2023): 429. https://doi.org/10.3892/ol.2023.14015