INHIBITORY EFFECTS OF COMBINED ADMINISTRATION OF UFT AND KRESTIN ON INTRAPERITONEAL METASTASES IN MICE
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- Published online on: July 1, 1994 https://doi.org/10.3892/or.1.4.727
- Pages: 727-730
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Abstract
In this study we investigated the effect of combined administration of UFT and Krestin (PSK) on the growth of intraperitoneal metastasis and temporal changes in the immune-endocrine system under this immunochemotherapy. At 7 days, Plasma ACTH levels of the PSK group were significantly lower than that of the control group (p<0.01). At 14 days, the tumor weight in the combined and the PSK alone group was significantly decreased, compared to the control group (p<0.05). Serum IAP levels of the UFT group were significantly lower than that of the control group (p<0.05). Serum cortisol levels of the combined group were lower than that of the other groups.