search button

TTF1 GENE-EXPRESSION IN HUMAN PROLIFERATING THYROID-DISEASES

  • Authors:
    • E PERLINO
    • S MAENZA
    • E MARRA
    • A CIAMPOLILLO
    • GA MARRA
    • O DEROBERTIS
    • R GIORGINO
    • E QUAGLIARIELLO

  • View Affiliations

  • Published online on: November 1, 1994     https://doi.org/10.3892/or.1.6.1097
  • Pages: 1097-1100
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

TTF1 mRNA expression in the thyroid gland from 30 patients with thyroid proliferating diseases and 4 healthy donors used as normal controls was investigated using Northern blot analysis. Six patients affected by malignant thyroid carcinomas and six patients with adenoma were examined; moreover 18 patients with non malignant proliferating disease such as multinodular goiters were investigated. Determination of TTF1 mRNA revealed a significant decrease of the steady state mRNA levels in carcinomas and adenomas as compared to normal tissues. On the contrary, in patients affected by multinodular goiters variations were observed that seemed not to be directly associated with the pathological conditions.

Related Articles

Journal Cover

November 1994
Volume 1 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 3.8
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 8.5
  • CiteScore Rank: Q1: #74/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.719
  • SCImago Journal Rank (SJR): 0.864
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
PERLINO E, MAENZA S, MARRA E, CIAMPOLILLO A, MARRA G, DEROBERTIS O, GIORGINO R and QUAGLIARIELLO E: TTF1 GENE-EXPRESSION IN HUMAN PROLIFERATING THYROID-DISEASES. Oncol Rep 1: 1097-1100, 1994.
APA
PERLINO, E., MAENZA, S., MARRA, E., CIAMPOLILLO, A., MARRA, G., DEROBERTIS, O. ... QUAGLIARIELLO, E. (1994). TTF1 GENE-EXPRESSION IN HUMAN PROLIFERATING THYROID-DISEASES. Oncology Reports, 1, 1097-1100. https://doi.org/10.3892/or.1.6.1097
MLA
PERLINO, E., MAENZA, S., MARRA, E., CIAMPOLILLO, A., MARRA, G., DEROBERTIS, O., GIORGINO, R., QUAGLIARIELLO, E."TTF1 GENE-EXPRESSION IN HUMAN PROLIFERATING THYROID-DISEASES". Oncology Reports 1.6 (1994): 1097-1100.
Chicago
PERLINO, E., MAENZA, S., MARRA, E., CIAMPOLILLO, A., MARRA, G., DEROBERTIS, O., GIORGINO, R., QUAGLIARIELLO, E."TTF1 GENE-EXPRESSION IN HUMAN PROLIFERATING THYROID-DISEASES". Oncology Reports 1, no. 6 (1994): 1097-1100. https://doi.org/10.3892/or.1.6.1097