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Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence

  • Authors:
    • V. Tugnoli
    • A. Poerio
    • M. R. Tosi

  • View Affiliations

  • Published online on: August 1, 2004     https://doi.org/10.3892/or.12.2.353
  • Pages: 353-356
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Abstract

This study presents a multinuclear (1H, 13C and 31P) magnetic resonance spectroscopy characterization of the total lipid fraction extracted from different regions of a human kidney affected by a clear cell renal carcinoma. It was thus possible to demonstrate that cholesteryl esters and phosphatidylcholine are markers of the tumor infiltration, histologically confirmed, in the kidney medulla. The tumor tissue contains twice the amount of phospatidylcholine compared to normal cortex. The results appear relevant in light of new clinical applications based on the biochemical composition of human tissues.

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August 2004
Volume 12 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 3.8
  • Ranked Oncology
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  • CiteScore: 8.5
  • CiteScore Rank: Q1: #74/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.719
  • SCImago Journal Rank (SJR): 0.864
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Spandidos Publications style
Tugnoli V, Poerio A and Tosi MR: Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence. Oncol Rep 12: 353-356, 2004.
APA
Tugnoli, V., Poerio, A., & Tosi, M.R. (2004). Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence. Oncology Reports, 12, 353-356. https://doi.org/10.3892/or.12.2.353
MLA
Tugnoli, V., Poerio, A., Tosi, M. R."Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence". Oncology Reports 12.2 (2004): 353-356.
Chicago
Tugnoli, V., Poerio, A., Tosi, M. R."Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence". Oncology Reports 12, no. 2 (2004): 353-356. https://doi.org/10.3892/or.12.2.353