IMMUNOHISTOCHEMICAL DETECTION OF P53 PROTEIN AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SALIVARY-GLAND TUMORS

  • Authors:
    • SM WEN
    • T TSUJI
    • XW LI
    • Y MIMURA
    • K SASAKI
    • F SHINOZAKI
  • View Affiliations

  • Published online on: March 1, 1995     https://doi.org/10.3892/or.2.2.233
  • Pages: 233-236
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The expression of p53 protein and PCNA was immunohistochemically examined in 161 cases of salivary gland tumors. The p53 protein was positive in 23.8% (24/101) of malignant salivary gland tumors, while only one case of 60 pleomorphic adenomas was positive. p53 protein was frequently detectable in salivary duct carcinoma (60%), basal cell adenocarcinoma (66.7%), acinic cell carcinoma (53.3%) and undifferentiated carcinoma (50%), but was rarely seen in adenoid cystic carcinoma (17.2%) and mucoepidermoid carcinoma (0%). p53 protein was more frequently detectable in PCNA positive cases than in negative cases (p=0.0074).

Related Articles

Journal Cover

March 1995
Volume 2 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
WEN S, TSUJI T, LI X, MIMURA Y, SASAKI K and SHINOZAKI F: IMMUNOHISTOCHEMICAL DETECTION OF P53 PROTEIN AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SALIVARY-GLAND TUMORS. Oncol Rep 2: 233-236, 1995.
APA
WEN, S., TSUJI, T., LI, X., MIMURA, Y., SASAKI, K., & SHINOZAKI, F. (1995). IMMUNOHISTOCHEMICAL DETECTION OF P53 PROTEIN AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SALIVARY-GLAND TUMORS. Oncology Reports, 2, 233-236. https://doi.org/10.3892/or.2.2.233
MLA
WEN, S., TSUJI, T., LI, X., MIMURA, Y., SASAKI, K., SHINOZAKI, F."IMMUNOHISTOCHEMICAL DETECTION OF P53 PROTEIN AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SALIVARY-GLAND TUMORS". Oncology Reports 2.2 (1995): 233-236.
Chicago
WEN, S., TSUJI, T., LI, X., MIMURA, Y., SASAKI, K., SHINOZAKI, F."IMMUNOHISTOCHEMICAL DETECTION OF P53 PROTEIN AND PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SALIVARY-GLAND TUMORS". Oncology Reports 2, no. 2 (1995): 233-236. https://doi.org/10.3892/or.2.2.233