Radiation-induced heart disease
- Authors:
- Published online on: January 1, 1996 https://doi.org/10.3892/or.3.1.21
- Pages: 21-26
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Abstract
The recent improvement in radiation techniques and the associated significant prolongation of survival have resulted in a widespread utilization of mediastinal irradiation in patients with various neoplasms. However, a large number of experimental and clinical studies have clearly demonstrated that high-dose therapeutic mediastinal irradiation can produce delayed, severe cardiovascular disease. This review presents the data from the Literature regarding the pathogenesis, pathology, prevalence and clinical manifestation of the radiation-related heart disease.