Autocrine motility factor receptor expression as a prognostic factor in pulmonary adenocarcinoma
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- Published online on: September 1, 1997 https://doi.org/10.3892/or.4.5.949
- Pages: 949-951
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Abstract
Autocrine motility factor receptor (AMF-R) expression was studied immunologically in tissue specimens from 121 patients with pulmonary adenocarcinoma. AMF-R expression was correlated with lymph node metastasis and stage. The prognosis of AMF-R positive patients was poorer than that of AMF-R negative patients. Multivariate analysis showed that AMF-R expression had a significant influence on prognosis. Our findings suggest that AMF-R plays an important role in tumor progression and that AMF-R expression is a useful prognostic marker for pulmonary adenocarcinomas.