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Multicentric giant cell tumor with viral-like inclusions associated with Paget's disease of bone: a case treated by steroid therapy.

  • Authors:
    • A De Chiara
    • G Apice
    • F Fazioli
    • P Silvestro
    • G Carone
    • A Manco

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  • Published online on: March 1, 1998     https://doi.org/10.3892/or.5.2.317
  • Pages: 317-337
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Abstract

We report a case of giant cell tumor of bone (GCTB) associated with Paget's disease unsuccefully treated with radiotherapy for some years but dramatically reduced in size with high dose of dexamethasone within few days. An ultrastructural study showed intranuclear virus-like inclusions in the multinucleated giant cells. The patient was then switched to prednisone plus diclofenac and he is still in almost complete remission after two years. The patient was from Avellino area, a small town in Southern Italy.

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Mar-Apr 1998
Volume 5 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 3.8
  • Ranked Oncology
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  • CiteScore: 8.5
  • CiteScore Rank: Q1: #74/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.719
  • SCImago Journal Rank (SJR): 0.864
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Spandidos Publications style
De Chiara A, Apice G, Fazioli F, Silvestro P, Carone G and Manco A: Multicentric giant cell tumor with viral-like inclusions associated with Paget's disease of bone: a case treated by steroid therapy.. Oncol Rep 5: 317-337, 1998.
APA
De Chiara, A., Apice, G., Fazioli, F., Silvestro, P., Carone, G., & Manco, A. (1998). Multicentric giant cell tumor with viral-like inclusions associated with Paget's disease of bone: a case treated by steroid therapy.. Oncology Reports, 5, 317-337. https://doi.org/10.3892/or.5.2.317
MLA
De Chiara, A., Apice, G., Fazioli, F., Silvestro, P., Carone, G., Manco, A."Multicentric giant cell tumor with viral-like inclusions associated with Paget's disease of bone: a case treated by steroid therapy.". Oncology Reports 5.2 (1998): 317-337.
Chicago
De Chiara, A., Apice, G., Fazioli, F., Silvestro, P., Carone, G., Manco, A."Multicentric giant cell tumor with viral-like inclusions associated with Paget's disease of bone: a case treated by steroid therapy.". Oncology Reports 5, no. 2 (1998): 317-337. https://doi.org/10.3892/or.5.2.317