Effects of amphetamine on the development of Moloney sarcoma virus-induced tumors in mice.
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- Published online on: March 1, 1998 https://doi.org/10.3892/or.5.2.381
- Pages: 381-384
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Abstract
Experiments were conducted to evaluate the effects of amphetamine (0. 4 mg/kg) on the development of autochthonous tumors induced by the Moloney sarcoma virus (MSV) in Balb/c female mice. Enhancement of MSV-induced tumor incidence and tumor growth was observed, together with a delay in the usual prompt regression of the tumors, when mice were daily injected with amphetamine for 3 days after MSV-inoculation. However, no effects of amphetamine on tumor development were observed when it was administered during the 3 days before tumor inoculation.