Circulating levels of soluble intercellular adhesion molecule-1 in non-small cell lung cancer patients.

  • Authors:
    • F De Vita
    • S Infusino
    • A Auriemma
    • M Orditura
    • G Catalano
  • View Affiliations

  • Published online on: March 1, 1998     https://doi.org/10.3892/or.5.2.393
  • Pages: 393-399
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Intercellular adhesion molecule-1 has been implicated in tumor progression and metastasis. Like soluble forms of other membrane receptors, a circulating form of intercellular adhesion molecule-1 (sICAM-1) has been identified in the serum of healthy subjects and it has been found in malignant diseases at increased levels. This study evaluated the serum concentration of sICAM-1 in 112 patients with non-small cell lung cancer (NSCLC). Soluble ICAM-1 levels were significantly higher in all patients when compared with the controls; serum concentration of sICAM-1 correlated with clinical stage and tumor progression. These results suggest that elevated levels of serum ICAM-1 could be of prognostic importance in patients with NSCLC.

Related Articles

Journal Cover

Mar-Apr 1998
Volume 5 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
De Vita F, Infusino S, Auriemma A, Orditura M and Catalano G: Circulating levels of soluble intercellular adhesion molecule-1 in non-small cell lung cancer patients.. Oncol Rep 5: 393-399, 1998.
APA
De Vita, F., Infusino, S., Auriemma, A., Orditura, M., & Catalano, G. (1998). Circulating levels of soluble intercellular adhesion molecule-1 in non-small cell lung cancer patients.. Oncology Reports, 5, 393-399. https://doi.org/10.3892/or.5.2.393
MLA
De Vita, F., Infusino, S., Auriemma, A., Orditura, M., Catalano, G."Circulating levels of soluble intercellular adhesion molecule-1 in non-small cell lung cancer patients.". Oncology Reports 5.2 (1998): 393-399.
Chicago
De Vita, F., Infusino, S., Auriemma, A., Orditura, M., Catalano, G."Circulating levels of soluble intercellular adhesion molecule-1 in non-small cell lung cancer patients.". Oncology Reports 5, no. 2 (1998): 393-399. https://doi.org/10.3892/or.5.2.393