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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Mar-Apr 1999 Volume 6 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Mar-Apr 1999 Volume 6 Issue 2

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Article

Abnormal transcripts of FHIT gene in Chinese brain tumors.

  • Authors:
    • T C Tsai
    • H M Yang
    • Y L Wu
    • C W Chi
    • M D Chou
    • L S Lee
    • T J Chang
  • View Affiliations / Copyright

    Affiliations: Department of Medical Research and Education, Veterans General Hospital-Taipei, Taiwan 11217, Japan.
  • Pages: 345-353
    |
    Published online on: March 1, 1999
       https://doi.org/10.3892/or.6.2.345
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Abstract

FHIT located at chromosome 3p14.2 was discovered and proposed as a candidate tumor suppressor gene in several cancers. To determine whether the FHIT gene at 3p14.2 is altered in Chinese brain tumors, we examined 13 brain tumors for deletions within FHIT locus. Evaluation of the FHIT gene in the panel of brain tumors led to a comprehensive mutation analysis. The complete sequence of the FHIT gene was determined and deletions between exon 5-8 were found in all 13 cases. In addition, single point mutation of amino acid from two glioblastoma and one atypical meningioma cases and multiple amino acid mutations from one pituitary tumor were observed. Our results support the hypothesis that FHIT gene alteration is involved in tumorigenic development of human neoplasms.

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Copy and paste a formatted citation
Spandidos Publications style
Tsai T, Yang H, Wu Y, Chi C, Chou M, Lee L and Chang T: Abnormal transcripts of FHIT gene in Chinese brain tumors.. Oncol Rep 6: 345-353, 1999.
APA
Tsai, T., Yang, H., Wu, Y., Chi, C., Chou, M., Lee, L., & Chang, T. (1999). Abnormal transcripts of FHIT gene in Chinese brain tumors.. Oncology Reports, 6, 345-353. https://doi.org/10.3892/or.6.2.345
MLA
Tsai, T., Yang, H., Wu, Y., Chi, C., Chou, M., Lee, L., Chang, T."Abnormal transcripts of FHIT gene in Chinese brain tumors.". Oncology Reports 6.2 (1999): 345-353.
Chicago
Tsai, T., Yang, H., Wu, Y., Chi, C., Chou, M., Lee, L., Chang, T."Abnormal transcripts of FHIT gene in Chinese brain tumors.". Oncology Reports 6, no. 2 (1999): 345-353. https://doi.org/10.3892/or.6.2.345
Copy and paste a formatted citation
x
Spandidos Publications style
Tsai T, Yang H, Wu Y, Chi C, Chou M, Lee L and Chang T: Abnormal transcripts of FHIT gene in Chinese brain tumors.. Oncol Rep 6: 345-353, 1999.
APA
Tsai, T., Yang, H., Wu, Y., Chi, C., Chou, M., Lee, L., & Chang, T. (1999). Abnormal transcripts of FHIT gene in Chinese brain tumors.. Oncology Reports, 6, 345-353. https://doi.org/10.3892/or.6.2.345
MLA
Tsai, T., Yang, H., Wu, Y., Chi, C., Chou, M., Lee, L., Chang, T."Abnormal transcripts of FHIT gene in Chinese brain tumors.". Oncology Reports 6.2 (1999): 345-353.
Chicago
Tsai, T., Yang, H., Wu, Y., Chi, C., Chou, M., Lee, L., Chang, T."Abnormal transcripts of FHIT gene in Chinese brain tumors.". Oncology Reports 6, no. 2 (1999): 345-353. https://doi.org/10.3892/or.6.2.345
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