Cell death, dysglycemia and myocardial infarction (Review)
- Authors:
- Xiao‑Fang Tian
- Ming‑Xia Cui
- Shi‑Wei Yang
- Yu‑Jie Zhou
- Da‑Yi Hu
-
Affiliations: Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Department of Pharmacology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu 730000, P.R. China, 12th Ward, Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing 100029, P.R. China, Department of Cardiology, People's Hospital Affiliated to Peking University, Beijing 100044, P.R. China - Published online on: February 25, 2013 https://doi.org/10.3892/br.2013.67
- Pages: 341-346
This article is mentioned in:
Abstract
Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, Blagosklonny MV, El-Deiry WS, Golstein P, Green DR, Hengartner M, Knight RA, Kumar S, Lipton SA, Malorni W, Nunez G, Peter ME, Tschopp J, Yuan J, Piacentini M, Zhivotovsky B and Melino G: Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ. 16:3–11. 2009. View Article : Google Scholar : PubMed/NCBI | |
Whelan RS, Kaplinskiy V and Kitsis RN: Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol. 72:19–44. 2010. View Article : Google Scholar : PubMed/NCBI | |
Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D and Turner MB: Heart disease and stroke statistics - 2012 update: a report from the American Heart Association. Circulation. 125:e2–e220. 2012. View Article : Google Scholar : PubMed/NCBI | |
Spindel ON and Berk BC: Redox redux: protecting the ischemic myocardium. J Clin Invest. 122:30–32. 2012. View Article : Google Scholar : PubMed/NCBI | |
Lee YA, Yoo JH, Kim JH, Lee SH, Kim JH, Lim HH, Kang MJ, Chung HR, Lee SY, Shin CH and Yang SW: Independent relationships of obesity and insulin resistance with serum proinsulin level in prepubertal children with normal glucose tolerance. Pediatr Diabetes. 12:235–241. 2011. View Article : Google Scholar : PubMed/NCBI | |
Yang SW, Zhou YJ, Nie XM, Liu YY, Du J, Hu DY, Jia DA, Gao F, Hu B, Fang Z, Han HY, Liu XL, Yan ZX, Wang JL, Hua Q, Shi YJ and Li HW: Effect of abnormal fasting plasma glucose level on all-cause mortality in older patients with acute myocardial infarction: results from the Beijing Elderly Acute Myocardial Infarction Study (BEAMIS). Mayo Clin Proc. 86:94–104. 2011. View Article : Google Scholar | |
Yang SW, Zhou YJ, Liu YY, Hu DY, Shi YJ, Nie XM, Gao F, Hu B, Jia DA, Fang Z, Han HY, Wang JL, Hua Q and Li HW: Influence of abnormal fasting plasma glucose on left ventricular function in older patients with acute myocardial infarction. Angiology. 63:266–274. 2012. View Article : Google Scholar : PubMed/NCBI | |
Eguchi M, Kim YH, Kang KW, Shim CY, Jang Y, Dorval T, Kim KJ and Sweeney G: Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice. PLoS One. 7:e304502012. View Article : Google Scholar : PubMed/NCBI | |
Hsueh YC, Lee WH, Huang YY, et al: Hypoglycemia-induced non-ST segment-elevation myocardial infarction: an unusual complication of diabetes mellitus. Acta Cardiol Sin. 28:148–151. 2012. | |
Lim SY, Davidson SM, Mocanu MM, Yellon DM and Smith CC: The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore. Cardiovasc Drugs Ther. 21:467–469. 2007. View Article : Google Scholar : PubMed/NCBI | |
Festjens N, Vanden BT, Cornelis S and Vandenabeele P: RIP1, a kinase on the crossroads of a cell’s decision to live or die. Cell Death Differ. 14:400–410. 2007. | |
Lavrik IN, Mock T, Golks A, Hoffmann JC, Baumann S and Krammer PH: CD95 stimulation results in the formation of a novel death effector domain protein-containing complex. J Biol Chem. 283:26401–26408. 2008. View Article : Google Scholar : PubMed/NCBI | |
Kitsis RN and Molkentin JD: Apoptotic cell death ‘Nixed’ by an ER-mitochondrial necrotic pathway. Proc Natl Acad Sci USA. 107:9031–9032. 2010. | |
Youle RJ and Strasser A: The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol. 9:47–59. 2008. View Article : Google Scholar : PubMed/NCBI | |
Ashkenazi A and Dixit VM: Death receptors: signaling and modulation. Science. 281:1305–1308. 1998. View Article : Google Scholar : PubMed/NCBI | |
Kaufmann T, Tai L, Ekert PG, Huang DC, Norris F, Lindemann RK, Johnstone RW, Dixit VM and Strasser A: The BH3-only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest. Cell. 129:423–433. 2007. View Article : Google Scholar : PubMed/NCBI | |
Li H, Zhu H, Xu CJ and Yuan J: Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 94:491–501. 1998. View Article : Google Scholar : PubMed/NCBI | |
Levine B and Yuan J: Autophagy in cell death: an innocent convict. J Clin Invest. 115:2679–2688. 2005. View Article : Google Scholar : PubMed/NCBI | |
Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB and Tsujimoto Y: Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol. 6:1221–1228. 2004. View Article : Google Scholar : PubMed/NCBI | |
He C and Klionsky DJ: Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet. 43:67–93. 2009. View Article : Google Scholar : PubMed/NCBI | |
Yang YP, Liang ZQ, Gu ZL and Qin ZH: Molecular mechanism and regulation of autophagy. Acta Pharmacol Sin. 26:1421–1434. 2005. View Article : Google Scholar : PubMed/NCBI | |
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, Turk BE and Shaw RJ: AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol Cell. 30:214–226. 2008. View Article : Google Scholar : PubMed/NCBI | |
Hirotani S, Zhai P, Tomita H, Galeotti J, Marquez JP, Gao S, Hong C, Yatani A, Avila J and Sadoshima J: Inhibition of glycogen synthase kinase 3beta during heart failure is protective. Circ Res. 101:1164–1174. 2007. View Article : Google Scholar : PubMed/NCBI | |
Buller CL, Loberg RD, Fan MH, Zhu Q, Park JL, Vesely E, Inoki K, Guan KL and Brosius FC III: A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression. Am J Physiol Cell Physiol. 295:C836–C843. 2008. View Article : Google Scholar : PubMed/NCBI | |
Wang Y, Weiss LM and Orlofsky A: Host cell autophagy is induced by Toxoplasma gondiiand contributes to parasite growth. J Biol Chem. 284:1694–1701. 2009. View Article : Google Scholar : PubMed/NCBI | |
Robaglia C, Thomas M and Meyer C: Sensing nutrient and energy status by SnRK1 and TOR kinases. Curr Opin Plant Biol. 15:301–307. 2012. View Article : Google Scholar : PubMed/NCBI | |
Lum JJ, DeBerardinis RJ and Thompson CB: Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol. 6:439–448. 2005. View Article : Google Scholar : PubMed/NCBI | |
Costa R, Morrison A, Wang J, Manithody C, Li J and Rezaie AR: Activated protein C modulates cardiac metabolism and augments autophagy in the ischemic heart. J Thromb Haemost. 10:1736–1744. 2012. View Article : Google Scholar : PubMed/NCBI | |
Hardie DG: AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol. 8:774–785. 2007. View Article : Google Scholar : PubMed/NCBI | |
Arad M, Seidman CE and Seidman JG: AMP-activated protein kinase in the heart: role during health and disease. Circ Res. 100:474–488. 2007. View Article : Google Scholar : PubMed/NCBI | |
Bernales S, McDonald KL and Walter P: Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol. 4:e4232006. View Article : Google Scholar : PubMed/NCBI | |
Sakaki K, Wu J and Kaufman RJ: Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum. J Biol Chem. 283:15370–15380. 2008. View Article : Google Scholar : PubMed/NCBI | |
Chen Y, McMillan-Ward E, Kong J, Israels SJ and Gibson SB: Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci. 120:4155–4166. 2007. View Article : Google Scholar : PubMed/NCBI | |
Chen Y, McMillan-Ward E, Kong J, Israels SJ and Gibson SB: Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ. 15:171–182. 2008. View Article : Google Scholar : PubMed/NCBI | |
Juhasz G, Puskas LG, Komonyi O, Erdi B, Maroy P, Neufeld TP and Sass M: Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophilafat body. Cell Death Differ. 14:1181–1190. 2007. View Article : Google Scholar : PubMed/NCBI | |
Hannenhalli S, Putt ME, Gilmore JM, Wang J, Parmacek MS, Epstein JA, Morrisey EE, Margulies KB and Cappola TP: Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation. 114:1269–1276. 2006. View Article : Google Scholar : PubMed/NCBI | |
Sengupta A, Molkentin JD, Paik JH, DePinho RA and Yutzey KE: FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J Biol Chem. 286:7468–7478. 2011. View Article : Google Scholar : PubMed/NCBI | |
Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, Burden SJ, Di Lisi R, Sandri C, Zhao J, Goldberg AL, Schiaffino S and Sandri M: FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab. 6:458–471. 2007. View Article : Google Scholar : PubMed/NCBI | |
Xu P, Das M, Reilly J and Davis RJ: JNK regulates FoxO-dependent autophagy in neurons. Genes Dev. 25:310–322. 2011. View Article : Google Scholar : PubMed/NCBI | |
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD and Levine B: Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell. 122:927–939. 2005. View Article : Google Scholar : PubMed/NCBI | |
Sugishita Y, Watanabe M and Fisher SA: The development of the embryonic outflow tract provides novel insights into cardiac differentiation and remodeling. Trends Cardiovasc Med. 14:235–241. 2004. View Article : Google Scholar : PubMed/NCBI | |
Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science. 267:1456–1462. 1995. View Article : Google Scholar : PubMed/NCBI | |
Lorenzen JM, David S, Richter A, de Groot K, Kielstein JT, Haller H, Thum T and Fliser D: TLR-4+peripheral blood monocytes and cardiovascular events in patients with chronic kidney disease - a prospective follow-up study. Nephrol Dial Transplant. 26:1421–1424. 2011.PubMed/NCBI | |
Lockshin RA and Zakeri Z: Cell death in health and disease. J Cell Mol Med. 11:1214–1224. 2007. View Article : Google Scholar | |
Clarke M, Bennett M and Littlewood T: Cell death in the cardiovascular system. Heart. 93:659–664. 2007. View Article : Google Scholar | |
Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, Hambleton MA, Brunskill EW, Sayen MR, Gottlieb RA, Dorn GW, Robbins J and Molkentin JD: Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature. 434:658–662. 2005. View Article : Google Scholar : PubMed/NCBI | |
Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, Inohara H, Kubo T and Tsujimoto Y: Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature. 434:652–658. 2005. View Article : Google Scholar : PubMed/NCBI | |
Lee P, Sata M, Lefer DJ, Factor SM, Walsh K and Kitsis RN: Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. Am J Physiol Heart Circ Physiol. 284:H456–H463. 2003. View Article : Google Scholar : PubMed/NCBI | |
Jeremias I, Kupatt C, Martin-Villalba A, Habazettl H, Schenkel J, Boekstegers P and Debatin KM: Involvement of CD95/Apo1/Fas in cell death after myocardial ischemia. Circulation. 102:915–920. 2000. View Article : Google Scholar : PubMed/NCBI | |
Kurrelmeyer KM, Michael LH, Baumgarten G, Taffet GE, Peschon JJ, Sivasubramanian N, Entman ML and Mann DL: Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci USA. 97:5456–5461. 2000. View Article : Google Scholar | |
Burchfield JS, Dong JW, Sakata Y, Gao F, Tzeng HP, Topkara VK, Entman ML, Sivasubramanian N and Mann DL: The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart. Circ Heart Fail. 3:157–164. 2010. View Article : Google Scholar : PubMed/NCBI | |
Kajstura J, Cheng W, Reiss K, Clark WA, Sonnenblick EH, Krajewski S, Reed JC, Olivetti G and Anversa P: Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest. 74:86–107. 1996.PubMed/NCBI | |
Zhao ZQ and Vinten-Johansen J: Myocardial apoptosis and ischemic preconditioning. Cardiovasc Res. 55:438–455. 2002. View Article : Google Scholar : PubMed/NCBI | |
Chen Z, Chua CC, Ho YS, Hamdy RC and Chua BH: Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice. Am J Physiol Heart Circ Physiol. 280:H2313–H2320. 2001.PubMed/NCBI | |
Hochhauser E, Cheporko Y, Yasovich N, Pinchas L, Offen D, Barhum Y, Pannet H, Tobar A, Vidne BA and Birk E: Bax deficiency reduces infarct size and improves long-term function after myocardial infarction. Cell Biochem Biophys. 47:11–20. 2007. View Article : Google Scholar : PubMed/NCBI | |
Olivetti G, Quaini F, Sala R, Lagrasta C, Corradi D, Bonacina E, Gambert SR, Cigola E and Anversa P: Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart. J Mol Cell Cardiol. 28:2005–2016. 1996. View Article : Google Scholar : PubMed/NCBI | |
Fliss H and Gattinger D: Apoptosis in ischemic and reperfused rat myocardium. Circ Res. 79:949–956. 1996. View Article : Google Scholar : PubMed/NCBI | |
Kirshenbaum LA: Regulation of autophagy in the heart in health and disease. J Cardiovasc Pharmacol. 60:1092012. View Article : Google Scholar : PubMed/NCBI | |
Nishida K, Kyoi S, Yamaguchi O, Sadoshima J and Otsu K: The role of autophagy in the heart. Cell Death Differ. 16:31–38. 2009. View Article : Google Scholar : PubMed/NCBI | |
Tucka J, Bennett M and Littlewood T: Cell death and survival signalling in the cardiovascular system. Front Biosci. 17:248–261. 2012. View Article : Google Scholar : PubMed/NCBI | |
Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, Taniike M, Omiya S, Mizote I, Matsumura Y, Asahi M, Nishida K, Hori M, Mizushima N and Otsu K: The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med. 13:619–624. 2007. View Article : Google Scholar : PubMed/NCBI | |
Sciarretta S, Zhai P, Shao D, Maejima Y, Robbins J, Volpe M, Condorelli G and Sadoshima J: Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome. Circulation. 125:1134–1146. 2012. View Article : Google Scholar | |
Gustafsson AB and Gottlieb RA: Autophagy in ischemic heart disease. Circ Res. 104:150–158. 2009. View Article : Google Scholar : PubMed/NCBI | |
Brady NR, Hamacher-Brady A, Yuan H and Gottlieb RA: The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores. FEBS J. 274:3184–3197. 2007. View Article : Google Scholar : PubMed/NCBI | |
Malhotra A, Kang BP, Hashmi S and Meggs LG: PKCepsilon inhibits the hyperglycemia-induced apoptosis signal in adult rat ventricular myocytes. Mol Cell Biochem. 268:169–173. 2005. View Article : Google Scholar : PubMed/NCBI | |
Capes SE, Hunt D, Malmberg K and Gerstein HC: Stress hyper-glycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet. 355:773–778. 2000. View Article : Google Scholar : PubMed/NCBI | |
Risso A, Mercuri F, Quagliaro L, Damante G and Ceriello A: Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in culture. Am J Physiol Endocrinol Metab. 281:E924–E930. 2001.PubMed/NCBI | |
Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T, Levine B and Sadoshima J: Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res. 100:914–922. 2007. View Article : Google Scholar : PubMed/NCBI | |
Zhang JL, Lu JK, Chen D, Cai Q, Li TX, Wu LS and Wu XS: Myocardial autophagy variation during acute myocardial infarction in rats: the effects of carvedilol. Chin Med J (Engl). 122:2372–2379. 2009.PubMed/NCBI |