Paola Sena
University of Modena and Reggio Emilia, Italy
- Publications: 40
- Citations: 16
- Keywords: colorectal cancer, inflammation, autophagy
Short Bio
- Education 2005: PhD in Human Colorectal Oncology, University of Modena, Italy 1999 B.S degree Position Held 2005 – Researcher BIO/17-Histology, University of Modena and Reggio Emilia, Italy 2002 - 2005: PhD in Human Colorectal Oncology, Department of Human Anatomical Sciences, University of Modena, Italy (PhD Thesis Research Project: Role of Wnt pathway in human colorectal cancer). Societies SIAI - Italian Society of Anatomy and Histology Italian ABCD - Italian Association of Cell Biology and Differentiation . Organizer of the following workshop 2013 -The role of inflammation in the colorectal carcinogenesis, Modena, Italy. Invited Lecturer “Inflammation process and pre-malignant lesions in human colorectal cancer” Academic service 2021- Member of the Council of the Department of Surgery Medicine Dentistry and Morphological Sciences with interest in Transplantation, Oncology and Regenerative Medicine – University of Modena and Reggio Emilia. 2021- Member of the Didactic Committee of the Department of Surgery Medicine Dentistry and Morphological Sciences with interest in Transplantation, Oncology and Regenerative Medicine – University of Modena and Reggio Emilia. 2021- Vice-president of the degree course in Biomedical Technique, University of Modena, and Reggio Emilia. Academic teaching activity 2018- Holder of Histology teaching for: Biomedical Technique degree(3CFU) psychiatric rehabilitators Degree (3CFU) Biotechnology Degree (6CFU) Medicine and surgery degree (1CFU) Editorial activity Member of the Editorial Board of Experimental and Therapeutic Medicine., March, 2020 Guest Editor of Special Issue "Colorectal Cancer and Adjacent Normal Mucosa Differ in Apoptotic and Inflammatory Protein Expression" for International Journal of Molecular Science, october,2021. Member of the Editorial Board of International Journal of Molecular Science, November, 2021 Research activity The overall research activity of Paola Sena in a temporal succession has involved the fields of cell signaling focused on Wnt signaling in human colorectal cancer. Cellular signaling is a complex ballet of molecules interacting and stimulating surrounding proteins, lipids, and ions, resulting in cytoskeletal reorganization, modulation of differentiation and induction of gene expression. During the first years of her scientific path, the research activity was focused on morphological evaluation of Microadenomas in human colorectal samples. During the last years, thanks to an interdisciplinary scientific approach, the research gradually moved to the study of the molecular signaling events on cell proliferation and differentiation in colorectal cancer. In particular, the signaling mechanism downstream the Wnt pathway were investigated in physiological conditions and upon drugs treatment. Of note, recently the focus is the analysis of new molecular regulators acting in the role of inflammation in the onset of human colorectal cancer
