Special nutrition in mouse developmental oocytes

  • Authors:
    • Ling Yu
    • Shu-Fang Wang
    • Yuan-Qing Yao
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  • Published online on: February 17, 2012     https://doi.org/10.3892/etm.2012.489
  • Pages: 823-827
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Abstract

Investigation of nutrition-related proteins in mouse oocytes and zygotes is crucial for the development of an effective therapy for patients with infertility. Currently, we are concerned with the role of nutrition in the process of oocyte development in order to better reveal the relationship between nutrition and infertility. We collected mouse oocytes at three different developmental stages: germinal vesicle (GV) stage, metaphase II-arrested (MII) stage and fertilized oocytes (zygotes). Semi-quantitative mass spectrometry and GeneMapper software were used to analyze nutrition-related proteins in these oocytes. Various specific proteins were abundantly expressed in the mouse oocytes. These proteins included heat shock proteins and Ybx2. Additional proteins which exist in important meta­bolism pathways also demonstrated differential expression among the three stages. We identified additional nutrition elements required for oocyte development and fertilization. The present study contributed to increased understanding of nutrition in the process of oocyte development, which may enhance the efficacy of therapy for patients with infertility.
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May 2012
Volume 3 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Yu L, Wang S and Yao Y: Special nutrition in mouse developmental oocytes. Exp Ther Med 3: 823-827, 2012
APA
Yu, L., Wang, S., & Yao, Y. (2012). Special nutrition in mouse developmental oocytes. Experimental and Therapeutic Medicine, 3, 823-827. https://doi.org/10.3892/etm.2012.489
MLA
Yu, L., Wang, S., Yao, Y."Special nutrition in mouse developmental oocytes". Experimental and Therapeutic Medicine 3.5 (2012): 823-827.
Chicago
Yu, L., Wang, S., Yao, Y."Special nutrition in mouse developmental oocytes". Experimental and Therapeutic Medicine 3, no. 5 (2012): 823-827. https://doi.org/10.3892/etm.2012.489