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Cancer stem cells - from initiation to elimination, how far have we reached? (Review)

  • Authors:
    • Kamal Akhtar
    • Wendy Bussen
    • Shaun P. Scott

  • View Affiliations

  • Published online on: June 1, 2009     https://doi.org/10.3892/ijo_00000278
  • Pages: 1491-1503
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Cancer stem cells (CSCs) are rare tumor cells that have the potential to proliferate, self-renew and induce tumorigenesis. Over the past few years, CSCs have been isolated from several different tumors and when implanted into immune-deficient mice, generate tumors that are identical to the parental tumors. In this review, we summarize the current literature on CSCs, which suggests that since these cells have the ability to drive tumor formation, specifically targeting them may lead to more effective therapies against tumors.

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Journal Cover

June 2009
Volume 34 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Journal Metrics
  • Impact Factor: 4.5
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 9.6
  • CiteScore Rank: Q1: #66/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.88
  • SCImago Journal Rank (SJR): 1.099
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Spandidos Publications style
Akhtar K, Bussen W and Scott SP: Cancer stem cells - from initiation to elimination, how far have we reached? (Review). Int J Oncol 34: 1491-1503, 2009.
APA
Akhtar, K., Bussen, W., & Scott, S.P. (2009). Cancer stem cells - from initiation to elimination, how far have we reached? (Review). International Journal of Oncology, 34, 1491-1503. https://doi.org/10.3892/ijo_00000278
MLA
Akhtar, K., Bussen, W., Scott, S. P."Cancer stem cells - from initiation to elimination, how far have we reached? (Review)". International Journal of Oncology 34.6 (2009): 1491-1503.
Chicago
Akhtar, K., Bussen, W., Scott, S. P."Cancer stem cells - from initiation to elimination, how far have we reached? (Review)". International Journal of Oncology 34, no. 6 (2009): 1491-1503. https://doi.org/10.3892/ijo_00000278